CRISPR News and Research

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In the late 1980s and mid-1990s, genomes of diverse lineages of bacteria and archaea (the latter representing a domain of single-celled prokaryotic microorganisms) revealed clusters of regularly interspaced short palindromic repeats, known today under the abbreviation CRISPR. Later it was found that these repeat sequences (previously considered disparate) share a common set of features.

Scientists use mRNA delivery to enhance muscle power

Mutations that cause muscle atrophy can be corrected using the CRISPR-Cas9 gene-editing tool.

16 Mar 2022

Yale researchers find a way to 'supercharge' tumor-attacking T cells

Yale scientists have identified a way to "supercharge" tumor-attacking T cells, a finding that may not only improve the effectiveness of a promising type of cell-based cancer immunotherapy but also expand the number of cancers it can treat.

11 Mar 2022

Unusual partners aid new blood vessel development

Insufficient oxygen to an area like the heart or legs, called hypoxia, is a cue to our bodies to make more blood vessels, and scientists have found some unusual partners are key to making that happen.

9 Mar 2022

New technique controls gene activity without altering the DNA sequence of the genome

By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical "off switches" that silence them.

7 Mar 2022

Researchers redevelop Cas9 that is unlikely to cut the wrong DNA

At times, the molecular machinery makes alterations to the wrong part of a host’s genome, generating the likelihood of an effort to repair a genetic mutation.

4 Mar 2022

Attacking a protein in prostate cancer cells stops the disease spread, research finds

Cedars-Sinai scientists discovered that attacking a protein present in prostate cancer cells could stop the disease from further spreading to various other parts of the body.

2 Mar 2022

Researchers discover a new epigenetic mark in small freshwater animals

Your DNA holds the blueprint to build your body, but it's a living document: Adjustments to the design can be made by epigenetic marks.

1 Mar 2022

US research reveals the role of Heparan Sulfate in obesity

AMSBIO reports how researchers at the Washington University School of Medicine (St. Louis, USA) have used their 10E4 Heparan Sulfate (HS) antibody in pioneering obesity research to quantify the role of HS in the process of intercellular mitochondria transfer to macrophages.

From AMS Biotechnology 1 Mar 2022

TGen collaborates with Deepcell to employ AI for analyzing single cell morphology

The Translational Genomics Research Institute, an affiliate of City of Hope, is partnering with a Silicon Valley firm to become one of the first research institutes in the world to employ a new Artificial Intelligence-powered imaging and sorting technology to classify and isolate individual diseased cells.

23 Feb 2022

Novel tool for genome-wide design, evaluation of gRNA sequences for CRISPR experiments

Commercially viable biofuel crops are vital to reducing greenhouse gas emissions, and a new tool developed by the Center for Advanced Bioenergy and Bioproducts Innovation should accelerate their development -; as well as genetic editing advances overall.

18 Feb 2022

CRISPR/Cas9-mediated gene editing is now feasible in ticks

Researchers have successfully used CRISPR-Cas9 to edit the genomes of the black-legged tick. To accomplish this feat, they developed an embryo injection protocol that overcame a major barrier in the field.

17 Feb 2022

UCI biologists discover how a gene variant protects against Alzheimer's disease

While the word "mutation" may conjure up alarming notions, a mutation in brain immune cells serves a positive role in protecting people against Alzheimer's disease.

15 Feb 2022

New methodology for 'compressing' extensive genetic data libraries to more manageable sizes

In image compression, a large file that could be cumbersome to store or share loses a small amount of visual information.

From Penn State University 15 Feb 2022

Genetic mutation introduced into human genome protects against Alzheimer’s disease, research says

Scientists were successful in editing the genome of human cells cultured in vitro to introduce a mutation offering protection from Alzheimer’s disease.

14 Feb 2022

Study creates a new wheat mutant with resistance to disease

Chinese scientists explained their use of genome editing to produce significant disease resistance without any growth problems in a study published online in Nature.

14 Feb 2022

Three proteins as potential new therapeutic targets in movement disorders

Three members of a family of proteins have been identified that are important to helping us fine tune the activity of brain chemicals which enable us to walk or stand at will, scientists report.

11 Feb 2022

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

An international team led by the Case Western Reserve University School of Medicine has discovered novel properties of the protein Gasdermin B that promotes repair of cells lining the gastrointestinal tract in people with chronic inflammatory disorders like Crohn's disease and ulcerative colitis.

8 Feb 2022

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