Efficacy News and Research

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Gut microbiota may play a role in resistance to blood pressure medicines

Almost half of the U.S. adult population has high blood pressure - or hypertension - and about 20% of these patients have treatment-resistant hypertension.

6 Apr 2022

Experimental "gene silencing" therapy reduces a important driver of heart disease risk by up to 98%

Findings from a new Cleveland Clinic-led phase 1 trial show that an experimental "gene silencing" therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%.

4 Apr 2022

Researchers discover a unique technique to fight hospital-borne disease

A study team developed an early-stage therapy that sabotages the pump and restores antibiotic efficiency by disclosing the structure of a protein needed by bacteria to pump out antibiotics.

From New York University (NYU) 4 Apr 2022

CAR-T cell treatment via implantable biotechnology more effective in combating cancer

Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed an implantable biotechnology that produces and releases CAR-T cells for attacking cancerous tumors.

25 Mar 2022

New database provides extensive information on kinase-associated neural protein phosphorylation

Biological functions rely on accurate cellular communication involving different molecules. Most major signaling pathways involved in such communication, called signal transduction, often involve a family of kinases—enzymes catalyzing the transfer of phosphates between specific substrate molecules.

17 Mar 2022

Novel method to sneak large drug-carrying biological molecules into cells

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a novel method of delivering drugs into human cells using large biological molecules, by first encasing them in a protein-based microdroplet.

From Nanyang Technological University Singapore (NTU Singapore) 17 Mar 2022

Researchers develop an antibody as a tool for opening the blood-brain barrier

The brain is composed of billions of neurons-; vulnerable cells that require a protective environment to function properly.

17 Mar 2022

Researchers conduct a detailed study of skin layer, likely to assist in new products and treatments

Scientists have precisely studied the skin’s resistant barrier layer, producing the most thorough molecular map of its form to aid in the creation of novel skin products and treatments.

16 Mar 2022

Cellular therapy leads to meaningful functional improvements in DMD patients

A clinical trial at UC Davis Health and six other sites showed that a cellular therapy offers promise for patients with late-stage Duchenne muscular dystrophy (DMD), a rare genetic disorder causing muscle loss and physical impairments in young people.

From The University of California, Davis 14 Mar 2022

Researchers optimize a route for two-step synthesis of antiviral plant protectant

Plant viruses are of great variety and harm. Virus disease pandemics and epidemics were estimated to have a global economic impact in the tens of billions of dollars.

3 Mar 2022

Researchers describe the structural basis of how antibodies may neutralize SARS-CoV-2 variants

The SARS-CoV-2 virus is continuously evolving and structural changes to the virus may impact the efficacy of antibody therapies and vaccines.

2 Mar 2022

Study investigates the relationship between healthy tissue repair and cancer growth

Scientists at the Francis Crick Institute have revealed how a mechanism involved in the regeneration of tissue can help the spread of cancer.

28 Feb 2022

Study identifies a new cancer cell state related to poor treatment response in ovarian cancer patients

The prognosis for ovarian cancer patients is grim: less than half of high-grade serous ovarian cancer (HGSC) patients survive past five years from diagnosis. Initially, the tumors typically respond well to chemotherapy but become resistant after repeated treatments, enabling the cancer to regrow.

24 Feb 2022

Experts identify a potential new target for antimalarial development

A protein that plays an important biological role in the malaria-causing parasite has been discovered by an international research team.

18 Feb 2022

Experts trigger apoptosis in leukemia cells by disrupting their energy maintenance mechanism

A group of researchers from UNIGE in Switzerland and Inserm in France has discovered a previously unknown process that could lead to the creation of novel medicines.

18 Feb 2022

Discovery of chiral evasion could lead to more resilient inhibitors, better drug designs

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial infection that has become resistant to most of the antibiotics used to treat regular staph infections.

18 Feb 2022

Human nose organoids reveal the first events of SARS-CoV-2 and RSV infection

Preclinical models that recapitulate aspects of human airway disease are essential for the advancement of novel therapeutics and vaccines.

16 Feb 2022

A simple route for synthesizing fungal compound and its derivatives

The solutions to many of humanity's problems can be found within nature. For instance, who could have guessed that an antibiotic as powerful as penicillin would be found in a common mold, or that the drug aspirin would be derived from the bark of the willow tree?

From Tokyo University of Science 10 Feb 2022

Scientists design an open microfluidic system for excellent recovery of purified DNA

In the war against cancer, the first step towards treating them is an accurate diagnosis of the problem. A technique that helps plan a better course of treatment is a biopsy.

7 Feb 2022

Peptide-enhanced, biological cancer drug may help treat breast cancer metastasis to bone

A moderate amount of a peptide-enhanced, biological cancer drug goes a long way in treating breast cancers that metastasize to the bone.

25 Jan 2022

Efficacy News and Research

Gut microbiota may play a role in resistance to blood pressure medicines

Experimental "gene silencing" therapy reduces a important driver of heart disease risk by up to 98%

Researchers discover a unique technique to fight hospital-borne disease

CAR-T cell treatment via implantable biotechnology more effective in combating cancer

New database provides extensive information on kinase-associated neural protein phosphorylation

Novel method to sneak large drug-carrying biological molecules into cells

Researchers develop an antibody as a tool for opening the blood-brain barrier

Researchers conduct a detailed study of skin layer, likely to assist in new products and treatments

Cellular therapy leads to meaningful functional improvements in DMD patients

Researchers optimize a route for two-step synthesis of antiviral plant protectant

Researchers describe the structural basis of how antibodies may neutralize SARS-CoV-2 variants

Study investigates the relationship between healthy tissue repair and cancer growth

Study identifies a new cancer cell state related to poor treatment response in ovarian cancer patients

Experts identify a potential new target for antimalarial development

Experts trigger apoptosis in leukemia cells by disrupting their energy maintenance mechanism

Discovery of chiral evasion could lead to more resilient inhibitors, better drug designs

Human nose organoids reveal the first events of SARS-CoV-2 and RSV infection

A simple route for synthesizing fungal compound and its derivatives

Scientists design an open microfluidic system for excellent recovery of purified DNA

Peptide-enhanced, biological cancer drug may help treat breast cancer metastasis to bone

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