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Gut dysbiosis in people with Huntington's disease may offer a potential target for future treatment

A world first clinical study of the gut microbiome in people with Huntington's disease (HD) has found that it is not just a disease of the brain, but also of the body.

7 Aug 2020

Genes linked to Down syndrome abnormalities may offer protection against solid tumors

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered that a set of genes with decreased expression in individuals with Down syndrome may lead to clinical abnormalities in this population, such as poor muscle development and heart valve problems.

6 Aug 2020

Enhancing Breast Cancer Therapy through Killing ‘Sleeper Cells’

AZoLifeSciences speaks to Dr. James Whittle and Professor Geoff Lindeman about their research in enhancing breast cancer therapy through killing sleeper cells.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 6 Aug 2020

Gut microbes shape our antibodies before we are infected by pathogens

B cells are white blood cells that develop to produce antibodies. These antibodies can bind to harmful foreign particles to stop them invading body cells.

6 Aug 2020

Epigenetics key to daily production of 10 billion blood cells without mistakes

Just one in 2,000 bone marrow cells are hematopoietic stem cells (HSC), but these are the source of the ten billion blood cells humans make every day.

6 Aug 2020

Discovery Could Lead To More Potent Garlic, Boosting Flavor And Bad Breath

For centuries, people around the world have used garlic as a spice, natural remedy, and pest deterrent, but they did not know how powerful garlic was.

6 Aug 2020

Researchers identify new mechanism of papillomavirus that tricks the human immune system

Certain antibodies are known to protect humans from viral infections—or perhaps not?

6 Aug 2020

Researchers develop new models to study molecular characteristics of lung and pancreatic cancers

Scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) report today the development of new models to study molecular characteristics of tumors of the lung and pancreas.

5 Aug 2020

Researchers discover genetic cause of severe auto inflammatory syndrome

Researchers from the Icahn School of Medicine used a novel genetic sequencing technology to identify the genetic cause of--and a treatment for--a previously unknown severe auto inflam-matory syndrome affecting an 18-year-old girl since infancy.

5 Aug 2020

Scientists explore the role of epigenetic regulator factors in embryonic development

A research team at the Max Planck Institute for Molecular Genetics in Berlin has explored the role of factors in embryonic development that do not alter the sequence of DNA, but only epigenetically modify its "packaging".

5 Aug 2020

New findings help to better understand the genetics of neuropsychiatric disorders

A new study led by NorthShore University HealthSystem (NorthShore) and the University of Chicago took a novel approach to identifying SNPs influencing the risk of neuropsychiatric disorders like schizophrenia, bipolar and major depressive disorder, the institutions announced today.

5 Aug 2020

Newly discovered 'mutation fog' linked to normal DNA repair process

Hypermutation is an unusual occurence that can lead to many nearby mutations at once, severely damaging our genetic material and potentially causing cancer.

5 Aug 2020

New study may offer a novel, potential target for treating breast cancer

According to researchers, G-quadruplexes have been demonstrated to play a crucial role in specific types of breast cancer for the first time.

5 Aug 2020

Identifying a new genetic cause of inherited neuropathy

Inherited mutations in a gene that keeps nerve cells intact were shown, for the first time, to be a driver of neuropathy known as Charcot-Marie-Tooth disease.

4 Aug 2020

Old part of immune system may influence severity of COVID-19

One of the immune system's oldest branches may be influencing the severity of COVID disease, according to a new study from researchers.

4 Aug 2020

Researchers develop CAR-T cell therapy based on TCR signal transduction

The T cell receptor (TCR) is a key receptor that is responsible for detecting tumor antigens in T cells.

4 Aug 2020

New study can help develop longevity-promoting drugs

Scientists have successfully dialed up and down the lifespan of creatures by changing the activity of proteins present in roundworm cells.

4 Aug 2020

Genetic analysis helps determine causal relationships between diabetes, obesity and NAFLD

Diabetes, obesity and nonalcoholic fatty liver disease (NAFLD) are all common diseases that can lead to serious health implications.

3 Aug 2020

Ecological stress within freshwater species can be detected with DNA metabarcoding

DNA or eDNA, for example, river water or, as in the case of the study by the team from the University of Duisburg-Essen (Essen, Germany) within the German Barcode of Life project (GBOL II): Vera Zizka, Dr Martina Weiss and Prof Florian Leese, from individuals in bulk samples.

3 Aug 2020

Detailed 3D structure provides a roadmap for tweaking CRISPR-Cas9–guided base editors

Within a mere eight years, CRISPR-Cas9 has become the go-to genome editor for both basic research and gene therapy.

31 Jul 2020

Genetic News and Research

Gut dysbiosis in people with Huntington's disease may offer a potential target for future treatment

Genes linked to Down syndrome abnormalities may offer protection against solid tumors

Enhancing Breast Cancer Therapy through Killing ‘Sleeper Cells’

Gut microbes shape our antibodies before we are infected by pathogens

Epigenetics key to daily production of 10 billion blood cells without mistakes

Discovery Could Lead To More Potent Garlic, Boosting Flavor And Bad Breath

Researchers identify new mechanism of papillomavirus that tricks the human immune system

Researchers develop new models to study molecular characteristics of lung and pancreatic cancers

Researchers discover genetic cause of severe auto inflammatory syndrome

Scientists explore the role of epigenetic regulator factors in embryonic development

New findings help to better understand the genetics of neuropsychiatric disorders

Newly discovered 'mutation fog' linked to normal DNA repair process

New study may offer a novel, potential target for treating breast cancer

Identifying a new genetic cause of inherited neuropathy

Old part of immune system may influence severity of COVID-19

Researchers develop CAR-T cell therapy based on TCR signal transduction

New study can help develop longevity-promoting drugs

Genetic analysis helps determine causal relationships between diabetes, obesity and NAFLD

Ecological stress within freshwater species can be detected with DNA metabarcoding

Detailed 3D structure provides a roadmap for tweaking CRISPR-Cas9–guided base editors

Genetics & Genomics - Second Edition eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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