Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

SARS-Cov-2 spike proteins can directly impact the function of blood-brain barrier

Like a key, SARS-CoV-2 - the virus that causes coronavirus disease 2019 (COVID-19) - attaches to specific molecules on the host cell surface, opening gateways into the cell interior.

30 Oct 2020

Individuals infected with mild-to-moderate COVID 19 mount a robust antibody response

The vast majority of individuals infected with mild-to-moderate COVID 19 mount a robust antibody response that is relatively stable for at least five months, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 28, in the journal Science.

29 Oct 2020

Researchers receive $2.6 million grant to examine tau-glycan interactions involved in Alzheimer's disease

Tangles of misfolded tau proteins in the brain are closely associated with memory loss in patients with Alzheimer's disease.

29 Oct 2020

Specific metabolites can predict COVID-19 mortality

A new study from Lawson Health Research Institute, Western University and University of Alberta suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites - small molecules broken down in the human body through the process of metabolism.

28 Oct 2020

Study indicates underlying molecular sources in COVID-19 variability

Humans have different susceptibilities to SARS-CoV-2, and eventually develop varying degrees of fatigue, fever, and breathing problems.

26 Oct 2020

Researchers uncover a new cellular mechanism for disposing of misfolded proteins

About 30 years ago, Dr. Richard Sifers set out on a journey to discover why people with a rare condition known as alpha1-antitrypsin (AAT) deficiency present with high variation in the severity of liver disease.

21 Oct 2020

UNM researchers identify medications that could help fight COVID-19 infection

University of New Mexico researchers who combed through a "library" of previously approved drugs believe they have identified a medication with the potential to help speed a patient's recovery from SARS-CoV-2 infection.

19 Oct 2020

Peptide therapy prevents overreaction of the immune system against infections

Individuals require enough action to remove offensive viruses or bacteria, but not so much that their body suffer a considerable damage.

From UC San Diego 15 Oct 2020

Researchers demonstrate healing power of extracellular vesicles on a heart-on-a-chip

Extracellular vesicles (EVs) -- nanometer sized messengers that travel between cells to deliver cues and cargo -- are promising tools for the next generation of therapies for everything from autoimmune and neurodegenerative diseases to cancer and tissue injury.

15 Oct 2020

Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

In a healthy brain, the multistep waste clearance process known as autophagy routinely removes and degrades damaged cell components - including malformed proteins like tau and toxic mitochondria.

13 Oct 2020

Researchers test the effect of hydroxychloroquine versus favipiravir in SARS-CoV-2−infected hamsters

Virologists at the KU Leuven Rega Institute have been working on two lines of SARS-CoV-2 research: searching for a vaccine to prevent infection, and testing existing drugs to see which one can reduce the amount of virus in infected people.

12 Oct 2020

High folic acid levels during pregnancy affect brain development of mouse embryos

A UC Davis MIND Institute study of pregnant mice found that high amounts of folic acid during pregnancy harmed the brain development of embryos.

From The University of California, Davis 6 Oct 2020

Researchers identify small molecules that appear to reduce cellular stress

For many, getting older can unfortunately mean an increased risk of illness from cardiovascular disease to cancer. University of Michigan scientists are actively researching the biological underpinnings of aging with the aim of developing interventions that could potentially help people live longer, healthier lives.

6 Oct 2020

Study shows patients can benefit from personalized cancer therapy

Scientists have shown that patients, who are receiving care for cancer, have a greater chance of surviving if they received personalized cancer treatment.

From UC San Diego 5 Oct 2020

Vacuolar Tauopathy: New, rare genetic form of dementia discovered

A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain -- which causes this newly discovered disease, as well as related neurodegenerative diseases like Alzheimer's Disease -- that could be targeted for new therapies. The study was published today in Science.

5 Oct 2020

Fungus in some organic pesticides can cause severe cob rot in maize

Protecting crops against pests and diseases is essential to ensure secure food supply. Around 95 percent of the food comes from conventional agriculture, which uses chemical pesticides to keep crops healthy. Increasingly, however, organic pesticides are also being sought as an alternative.

1 Oct 2020

Genetic test identifies patients with invasive lobular carcinoma at high risk of recurrence

New results to be presented at the 12th European Breast Cancer Conference show that a test, which looks at the activity of 70 genes in breast cancer tissue, is possible to use in the clinic to identify patients with invasive lobular carcinoma (ILC) that is at high risk of recurring and progressing.