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Unmasking XPD’s Mechanism in DNA Damage Detection and Repair

The way the protein XPD recognizes severe DNA damage and regulates its repair was uncovered by researchers at the University of Würzburg, under the direction of Caroline Kisker and Claudia Höbartner.

29 May 2024

Unraveling the Molecular Mechanisms of DNA Entanglement Resolution

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone.

12 Apr 2024

Scientists Create Lifelike Human Ear Replica with 3D Printing

Using state-of-the-art tissue engineering techniques and a 3D printer, researchers at Weill Cornell Medicine and Cornell Engineering have assembled a replica of an adult human ear that looks and feels natural.

1 Apr 2024

Protein RAD51 Acts as Guardian Against DNA Over-Replication

Every time a cell divides, its DNA is duplicated so that the two daughter cells have the same genetic material as their parent.

5 Mar 2024

Scientists Discover Dual Challenges in DNA Replication Process

Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied.

29 Feb 2024

DNA Repair Breakthrough: Scientists Reveal RecA's Precise Helix Navigation

Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a dangling single-strand end into intact double strands, and repairing the break based on the undamaged sequence.

22 Jan 2024

Computational Creation of Complex Protein All-α Structures

Based on their amino acid sequences, proteins fold into distinct three-dimensional structures that determine their function. While de novo protein design has advanced significantly, complex all-αproteins, in which α-helices are not stacked in a parallel fashion within three-dimensional structures, have not been as easily designed.

8 Jan 2024

New Method Designs Proteins With Complex Shapes

A team of researchers has developed an innovative method to design complicated all-α proteins, characterized by their non-uniformly arranged α-helices as seen in hemoglobin.

5 Jan 2024

A Dihydrofolate Reductase Single-Domain Protein Catenane

Professor Wen-Bin Zhang of the College of Chemistry and Molecular Engineering at Peking University and the Beijing Academy of Artificial Intelligence, along with Dr. Jing Fang of the same institution, are leading the study.

2 Jan 2024

Scientists Crack the Code for Artificial DNA

The genetic code is composed of just four letters representing the four nucleotides, which are the fundamental building blocks of DNA.

14 Dec 2023

Tokyo Metropolitan University Decodes DNA Repair Mechanisms

Tokyo Metropolitan University researchers have uncovered crucial aspects of the DNA repair mechanism within human bodies.

16 Nov 2023

Large Study Finds 187 New Genetic Variants Linked to Prostate Cancer

A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk -; 451 in all -; through a whole-genome analysis that ranks as the largest and most diverse investigation into prostate cancer genetics yet.

10 Nov 2023

Exploring Z-RNA’s Role in Immune Response

Quentin Vicens, an Assistant Professor of Biology and Biochemistry at the University of Houston, has been granted $1.2 million by the National Institute of General Medical Sciences to investigate the enigmatic Z-RNA structure found within human cells.

3 Nov 2023

Unveiling the Intricacies of Sperm Transformation

Scientists from Stockholm University have revealed the concealed complexities behind the transition of sperm from inert observers to active swimmers.

26 Oct 2023

Software Tool Paves the Way for Safer CRISPR Genome Editing

Researchers have developed a groundbreaking software tool known as DANGER analysis, offering a solution for safer and more precise genome editing.

23 Oct 2023

Creating a DNA Color Code With 16 Million Colors

Researchers at the University of Vienna have achieved a remarkable feat by developing fluorescent duplexes capable of producing up to 16 million colors.

18 Oct 2023

New Approach to Treating Age-Related Diseases by Targeting Aging Cells

A research team, led by Professor Ja Hyoung Ryu from the Department of Chemistry at UNIST, in collaboration with Professor Hyewon Chung from Konkuk University, has achieved a significant breakthrough in the treatment of age-related diseases.

5 Oct 2023

New Device Mimics Biology to Detect Disease

In living organisms, cells have a very high capacity to process and communicate information by moving molecules or ions through tiny channels that span the cell membrane. UC Santa Cruz Professor of Electrical and Computer Engineering Marco Rolandi's lab and collaborators at MIT have created a device that mimics this biological concept in order to detect disease.

19 Sep 2023

Versatile, Language-Based Approach Aids in the Design of New Proteins

Researchers discovered a new type of marine bacteria with distinct traits on the ocean floor.

30 Aug 2023

Study Shows How Genomic Topography Influences Where Cancer Mutations Arise

Researchers at the University of California San Diego have uncovered a connection between the topography of the human genome and the presence of mutations in human cancer. They found that certain regions of the genome, which exhibit unique features, act as hotspots for the accumulation of mutations.

25 Aug 2023