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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Squids Use RNA Recording to Change Key Proteins Dynamically

Octopuses, cuttlefish, and squid are members of the diverse family of marine creatures known as cephalopods. They can be found in every ocean, from warm tropical seas that are shallow to cold, abysmal depths.

9 Jun 2023

Can Temperature Influence the Octopus Neural Transcriptome?

Each cell has a finite set of instructions inscribed in its DNA. Life, on the other hand, is unpredictable, and when the situation changes, animals must change.

9 Jun 2023

Scientists Discover a New Step in the Differentiation of Precursor Cells Into Mature Basophils

Big changes often happen in small steps, and it's not always easy to see how we get from point A to point B.

8 Jun 2023

Assembled DNA Nanostructures Without the Use of Magnesium Yield Greater Stability

Researchers at the University at Albany’s RNA Institute have demonstrated a new approach to DNA nanostructure assembly that does not require magnesium.

7 Jun 2023

Molecular Rhythms of Malaria Parasites Sync With the Biological Clock of Human Hosts

Health officials warn that drug resistance could wipe out recent progress against malaria, particularly in Africa and southeast Asia.

7 Jun 2023

Hair Regrowth with Softening Stiff Hair Follicle Stem Cells with microRNA

According to a recent Northwestern Medicine study, hair follicle stem cells also turn rigid with age, making it harder for them to generate hair, just like people’s joints can stiffen and become more difficult for them to move around.

6 Jun 2023

The Role of Noncanonical Mechanism in the Evolution of miRNA Biogenesis

The Hong Kong University of Science and Technology (HKUST) research group, guided by Prof. Tuan Anh Nguyen, Assistant Professor of the Division of Life Science, used several advanced methods, including miRNA sequencing, pri-miRNA structure analysis, and high-throughput pri-miRNA cleavage assays for approximately 260,000 pri-miRNA sequences, to locate and thoroughly illustrate the newly identified noncanonical cleavage mechanism.

6 Jun 2023

New Delivery Mechanism Brings Messenger RNA to the Point of Need in Neurons

Brain cells manufacture proteins in every corner, including their long branches. Neurons missing this ability cause severe neurological disorders like disability and epilepsy.

5 Jun 2023

Fragments of RNA Viruses Discovered in Coral Partners’ Genomes

The DNA of symbiotic creatures living within reef-building corals has been found to contain the remains of ancient RNA viruses by an international team of marine researchers.

2 Jun 2023

Identifying How a Particular Riboswitch Regulates its Synthesis

Researchers across the world are in search of ways to combat bacteria that could evade the present arsenal of antibiotics. This is done as a measure to avoid a global health crisis.

2 Jun 2023

RNA Regulatory Mechanism Involving Stress Granules Directly Regulates Alzheimer’s Development

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."

2 Jun 2023

Charting a High-Resolution Roadmap for Regeneration of Pancreatic β Cells

At the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences (CAS), a research group headed by Professor Zhen Shao and the collaborators plotted a high-resolution roadmap for the process of pancreatic β cell regeneration by in vivo transdifferentiation from adult acinar cells with the help of a single-cell RNA sequencing (scRNA-seq) technology.

31 May 2023

Characterizing a Pivotal Time in Mammalian Embryonic Development

Many of life’s secrets are hidden in the initial stages of embryonic development. Unraveling these mysteries can aid in the understanding of early development and birth abnormalities, as well as the creation of innovative regenerative medicine treatments.

31 May 2023

New Insights Into How Genetic Variants Impact Gene Expression

The Department of Biomedical Informatics (DBMI) at the University of Colorado School of Medicine, in collaboration with the University of California San Francisco and Stanford University, has recently published a study that is the largest of its kind to focus on ancestry correlations with biomedical traits.

26 May 2023

Ex Vivo Expansion of HSCs Using a Novel Culture System

Hematopoietic stem cells (HSCs) are immature blood cells found in the bone marrow that can be stimulated to develop into any type of blood cell.

25 May 2023

Deep-Sequencing Identifies Over 10,000 Unique Genes in Cotton

TEs (transposable elements), particularly LTRs, are recognized to play a crucial role in defining basic genome organization and affecting functional gene expression. Insertion of TE or LTR fragments may also result in the formation of new transcription start sites (TSSs) in the host genome.

25 May 2023

Molecular Method Reveals Whether or Not Bacteria Respond to Antibiotics Within Minutes

Researchers at Karolinska Institutet have developed a molecular method able to detect whether or not bacteria respond to antibiotics within minutes.

23 May 2023

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

23 May 2023

Stimulating Cell DNA Repair Processes to Combat the Root Cause of Autism Spectrum Disorders

A new treatment option has been discovered for fragile X syndrome, which is the most common genetic cause of autism spectrum disorders and is defined by a hereditary repetition of certain nucleotides in the DNA sequence of the FMR1 gene. Researchers at Massachusetts General Hospital (MGH) carried out the study, which was published in the journal Cell.

22 May 2023

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

The enzyme variations of mitochondrial enoyl-CoA hydratase short-chain 1 (ECHS1) are dysfunctional. In Japan, they are mostly responsible for mitochondrial disease.

19 May 2023

RNA News and Research

Squids Use RNA Recording to Change Key Proteins Dynamically

Can Temperature Influence the Octopus Neural Transcriptome?

Scientists Discover a New Step in the Differentiation of Precursor Cells Into Mature Basophils

Assembled DNA Nanostructures Without the Use of Magnesium Yield Greater Stability

Molecular Rhythms of Malaria Parasites Sync With the Biological Clock of Human Hosts

Hair Regrowth with Softening Stiff Hair Follicle Stem Cells with microRNA

The Role of Noncanonical Mechanism in the Evolution of miRNA Biogenesis

New Delivery Mechanism Brings Messenger RNA to the Point of Need in Neurons

Fragments of RNA Viruses Discovered in Coral Partners’ Genomes

Identifying How a Particular Riboswitch Regulates its Synthesis

RNA Regulatory Mechanism Involving Stress Granules Directly Regulates Alzheimer’s Development

Charting a High-Resolution Roadmap for Regeneration of Pancreatic β Cells

Characterizing a Pivotal Time in Mammalian Embryonic Development

New Insights Into How Genetic Variants Impact Gene Expression

Ex Vivo Expansion of HSCs Using a Novel Culture System

Deep-Sequencing Identifies Over 10,000 Unique Genes in Cotton

Molecular Method Reveals Whether or Not Bacteria Respond to Antibiotics Within Minutes

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

Stimulating Cell DNA Repair Processes to Combat the Root Cause of Autism Spectrum Disorders

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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