Enzyme News and Research

RSS

Study discovers novel function for metabolic enzyme medium-chain acyl-CoA dehydrogenase

Scientists have come up with an innovative function for the metabolic enzyme medium-chain acyl-CoA dehydrogenase (MCAD) in glioblastoma (GBM).

1 Jun 2021

Researchers suggest new strategies for finding drugs that neutralize key enzymes

Scientists from the UK's University of Bath explore racemases - an important type of enzyme that is linked to certain cancers and other life-threatening diseases while also being critical to cell function - in a paper published in the prestigious journal Chemical Society Reviews. The scientists also propose new strategies for finding drugs that neutralize these enzymes.

From University of Bath 26 May 2021

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the body's immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim, and Freiburg discovered this mechanism and at the same time identified a way of reactivating the paralyzed immune system to fight the tumor.

25 May 2021

Exposure to even low levels of lead can trigger epigenetic changes

A research team from Brazil and Portugal has identified a link between a microRNA (miRNA) and the presence of lead in an organism.

18 May 2021

Refreshers develop new DNA sequencing method

An international research team headed by Michal Hocek of the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) and Charles University and Ciara K. O'Sullivan of Universitat Rovira i Virgili (URV) in Spain have developed a novel method for labeling DNA, which in the future can be used for sequencing DNA by means of electrochemical detection.

18 May 2021

New kind of biomolecule could play a vital role in the biology of all living things

Stanford researchers have discovered a new kind of biomolecule that could play a significant role in the biology of all living things.

18 May 2021

Study reveals mitochondrial enzyme plays a vital role in preventing ferroptosis

According to a study, the mitochondrial enzyme DHODH plays a significant and previously unknown function in preventing a form of cell death called ferroptosis.

13 May 2021

New drug-like compound designed to stop malaria in its tracks

Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop this compound into a potential first of its kind malaria treatment.

13 May 2021

Researchers identify the biosynthesis mechanism of new DNA nucleobases

DNA is made up of nucleobases, which are depicted by the letters G, A, T, and C. They are the foundation of the genetic code.

From Institut Pasteur 13 May 2021

New method to repartition carbon resources from carbohydrates to lipids in microalgae

A cross-institutional study has led to a new method for the repartition of carbon resources in microalgae from carbohydrates to lipids. It is anticipated that this process will be used to produce biofuel.

7 May 2021

Research uncovers how antibiotics target bacterial RNA Polymerase to inhibit gene transcription

The emergence and spread of new forms of resistance remains a concern that urgently demand new antibiotics. Transcription is a vital process in bacterial cell, where genetic information in DNA is transcribed to RNA for the translation of proteins that perform cellular function.

6 May 2021

Study reveals genetic mutation associated with exfoliation syndrome

A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore (GIS) and Bioprocessing Technology Institute (BTI), as well as Singapore Eye Research Institute (SERI), have identified a genetic mutation (functionally defective CYP39A1 gene) associated with exfoliation syndrome, the most common cause of glaucoma.

5 May 2021

Study finds how SARS-CoV-2 hijacks human cell machinery to disrupt the immune response

SARS-CoV-2 hijacks human cell machinery to disrupt the immune response, enabling it to cause infection, replicate, and cause disease.

4 May 2021

Study reveals a compound found in avocados helps in the treatment of leukemia

According to recent research at the University of Guelph, a compound found in avocados may one day lead to improved leukemia treatment.

4 May 2021

Researchers devise a small-molecule cocktail to protect stem cells from stress

Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function.

4 May 2021

New integrative genetic screening technology offers insights into role of DNA accessibility in cancer

In a new resource for the scientific community, published today in Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

30 Apr 2021

Enzyme News and Research

Study discovers novel function for metabolic enzyme medium-chain acyl-CoA dehydrogenase

Researchers suggest new strategies for finding drugs that neutralize key enzymes

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

Exposure to even low levels of lead can trigger epigenetic changes

Refreshers develop new DNA sequencing method

New kind of biomolecule could play a vital role in the biology of all living things

Study reveals mitochondrial enzyme plays a vital role in preventing ferroptosis

New drug-like compound designed to stop malaria in its tracks

Researchers identify the biosynthesis mechanism of new DNA nucleobases

New method to repartition carbon resources from carbohydrates to lipids in microalgae

Research uncovers how antibiotics target bacterial RNA Polymerase to inhibit gene transcription

Study reveals genetic mutation associated with exfoliation syndrome

Study finds how SARS-CoV-2 hijacks human cell machinery to disrupt the immune response

Study reveals a compound found in avocados helps in the treatment of leukemia

Researchers devise a small-molecule cocktail to protect stem cells from stress

New integrative genetic screening technology offers insights into role of DNA accessibility in cancer

Study discovers that mutations in a specific gene cause mitochondrial disease

New, altered form of prolactin receptor found to drive breast cancer

Study shows that autophagy plays a key role in messenger RNA degradation

Critical intermediate in normal cellular metabolism may lead to cell death

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics