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How Intensive Farming Could Increase the Risk of Epidemics

Professor Sam Sheppard speaks to AZoLifeSciences about his research on intensive farming and how it could increase the risk of epidemics.

From University of Bath 12 May 2020

Lipid metabolism enzyme regulates brain stem cell activity

Neural stem cells play a major role in the early development of the brain and they also continue to remain active throughout the lifetime.

11 May 2020

mTOR gene in GvHD patients regulates cell growth and cell survival

Mutations that occur in white blood cells can play a major role in abnormal immune profile following hematopoietic stem cell transplantation.

11 May 2020

Foxg1 gene works like a molecular knob to modulate electrical activity of the neurons

It works like a very fine "molecular knob" able to modulate the electrical activity of the neurons of our cerebral cortex, crucial to the functioning of our brain.

8 May 2020

Smart Use Of Genomic Data Needed In Species Conservation

A "step-change" in conservation is needed in order to help save species from extinction in the future, according to an academic at UEA.

5 May 2020

'Unnecessary' Genetic Complexity: A Spanner In The Works?

The massive international effort to map the entire human genome, completed in 2003, opened a new field we now know as personalized medicine.

5 May 2020

Molecular basis of rare neurodevelopmental condition reveals possible treatment

Like people, neurons need to talk to one another. But instead of turning thoughts into words, these cells convert electrical signals into chemical ones. For nearly 30 years, biochemist Edwin Chapman has studied how one protein triggers this crucial conversion.

4 May 2020

Choosing alternate pathways of DNA repair to limit harmful chromosomal rearrangements

Homologous recombination is an essential process of DNA repair to maintain genomic integrity of the organism.

From Osaka University 30 Apr 2020

Study finds utrophin-based therapy could be used to treat Duchenne muscular dystrophy

If an actor is not in a position to perform in the theatre, an understudy—preferably one with some practice in the role—can take that role on stage.

27 Apr 2020

Understanding evolution of early life may be trickier than previously thought

Biologists have long hoped to understand the nature of the earliest living organisms on Earth. If they could, they might then be able to say something about how, when, and where life arose on Earth, and perhaps by extension, whether life is common in the Universe.

23 Apr 2020

Researchers develop new molecular workflow to study single-cell genomics of diseases

Although advances in genetics and genomics reveal numerous disease-associated gene mutations, physicians and researchers still wrestle with the tricky challenge of linking those mutations to actual disease-causing processes.

23 Apr 2020

New study could lead to effective immunotherapy treatments for cancer patients

According to a study recently published in the eLife journal, researchers have devised a new method to chart the molecules present on tumor cells that indicate their presence to the immune system.

22 Apr 2020

Advanced simulations show how to improve efficiency of gene therapy

Diseases with a genetic cause could, in theory, be treated by supplying a correct version of the faulty gene.

20 Apr 2020

New algorithm predicts the evolution of genetic mutations in species

David McCandlish and Juannan Zhou, both quantitative biologists at the Cold Spring Harbor Laboratory, have designed a new algorithm that has predictive power, providing researchers the ability to observe the way particular genetic mutations combine to make crucial proteins change over the duration of a species’ evolution.

16 Apr 2020

Genetic architecture of life span is context dependent, study finds

Scientists believe about 25 percent of the differences in human life span is determined by genetics -- with the rest determined by environmental and lifestyle factors. But they don't yet know all the genes that contribute to a long life.

15 Apr 2020

Combined effect of rare mutations has negative impact on health and longevity

In a study published recently in the eLife journal, researchers have reported that the combined effects of rare and damaging mutations that occur at birth itself have adverse effects on health span and longevity.

13 Apr 2020

Study examines molecular causes of spondylocostal dysostosis

Researchers from EMBL Barcelona’s Ebisuya group collaborated with colleagues from RIKEN, Kyoto University, and Meijo Hospital in Nagoya, Japan, to investigate oscillating patterns of gene expression, coordinated across time and space within a tissue grown in vitro.

7 Apr 2020

UMSOM researchers uncover mechanism to explain role of genetic mutations in kidney disease

Researchers from the Center for Precision Disease Modeling at the University of Maryland School of Medicine have uncovered a mechanism that appears to explain how certain genetic mutations give rise to a rare genetic kidney disorder called nephrotic syndrome.

6 Apr 2020

Scientists Discover Gene That Increases Risk Of Alzheimer's Disease

Researchers from UBC and the Central South University (CSU) in China have for the first time identified a gene that increases the risk of Alzheimer's disease.

2 Apr 2020

Stem cell strategy can help improve the effectiveness of cardiac repair

Human stem cells have been typically perceived as one of the potential cell sources for cardiac regeneration treatment. However, the substandard performance following transplantation into the failing hearts has limited their applications in clinical use.

30 Mar 2020