Mammalian Cells News and Research

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Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

A compact CRISPR-Cas system, known as CasMINI, can be employed for gene-therapy and cell-engineering applications as it is easier to deliver into cells.

7 Sep 2021

Miniature CRISPR-Cas system expands applicability and implications further

For the first time, Stanford researchers have miniaturized CRISPR for mammalian gene editing, which magnifies the scope of CRISPR technology.

3 Sep 2021

New gene activity sensors, activators could help treat diabetes, cancer, and other disorders

People likely have apps on their cellphone. A new study at Rice University provides the viability of apps for actual cells.

19 Aug 2021

Researchers pinpoint a lack of best practices in mammalian cell culture

A group of KAUST researchers and co-workers in Saudi Arabia and the United States examined 810 randomly selected papers on mammalian cell lines.

16 Aug 2021

Human cells can convert RNA sequences into DNA

Cells include machinery that replicates DNA into a new set, and this, in turn, develops into a newly formed cell.

15 Jun 2021

AMSBIO's custom lentivectors enable visualization of cell nuclei and F-actin cytoskeleton in organoids

AMSBIO have supplied custom lentivectors to Francesco Pampaloni and his team at the Buchmann Institute for Molecular Life Sciences in Frankfurt, Germany allowing them to visualize cell nuclei and F-actin cytoskeleton in their organoids.

From AMS Biotechnology 1 Jun 2021

Research group reveals the essential role of Knl1 gene in plants

Dr. HAN Fangpu's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences reports the identification and functional study of the maize Knl1 gene in an article published online in PNAS.

12 May 2021

New CRISPR technology allows scientists to switch off any gene in human cells

Scientists have figured out how to modify CRISPR's basic architecture to extend its reach beyond the genome and into what's known as the epigenome -- proteins and small molecules that latch onto DNA and control when and where genes are switched on or off.

19 Apr 2021

Specific protein helps insect-eating plants trap their prey

A Venus flytrap will shut immediately just at the brush of an insect’s wing.

26 Mar 2021

ADAR1 protein offers a potential therapeutic target for cancer

A research team has discovered a new role of ADAR1 and found that the ADAR1p110 isoform controls genome stability at the ends of chromosomes.

15 Mar 2021

New technology identifies useful genetic designs more efficiently

Joshua Leonard, a synthetic biologist from Northwestern University, used electronic kits to create devices when he was a child.

23 Feb 2021

Study shows TALEN is five times more efficient than CRISPR-Cas9 tool

Using single-molecule imaging, scientists have compared the CRISPR-Cas9 and TALEN genome editing tools.

28 Jan 2021

UT Southwestern biochemist is honoured for breakthrough metabolic research

UT Southwestern Biochemist Benjamin Tu, Ph.D., is the recipient of the 2021 Edith and Peter O'Donnell Award in Science from TAMEST (The Academy of Medicine, Engineering and Science of Texas). He was chosen for his pioneering research on cellular roles of small molecule metabolites that may have relevance for cancer treatments and other diseases.

15 Jan 2021

Biochemist discovers hidden cellular machinery essential for higher-order life

In his first year of graduate school, Rice University biochemist Zachary Wright discovered something hidden inside a common piece of cellular machinery that's essential for all higher order life from yeast to humans.

7 Dec 2020

Study: Painkillers interfere with auxin flow essential for developmental processes in plants

For centuries humans were using willow barks to treat a headache or an inflamed tooth. Later, the active ingredient, the plant hormone salicylic acid, was used to develop painkillers like Aspirin.

2 Dec 2020

Researchers identify evolutionarily conserved pathway responsible for "closing down" gene activity

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a new and evolutionarily conserved pathway responsible for "closing down" gene activity in the mammalian cell.

3 Nov 2020

New DNA-cutting tool could advance gene editing for novel treatments

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's genome, according to a new study by UC San Francisco scientists.

21 Oct 2020