Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Using nanoparticles to carry drugs across the blood-brain barrier

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023

Experts reveal the link between necrosis, circulating tumor cells, and cancer metastasis

A tumor's necrotic core contains factors that appear to promote metastasis, or the seeding of tumors cells throughout the body, according to a new study in rats by researchers at Fred Hutchinson Cancer Center.

28 Feb 2023

Reversal of ADAR1 hyper-editing with small molecule inhibitor

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

17 Feb 2023

Scientists define four cancer molecular subtypes using PDX models

Metastasis, the process by which cancer cells leave the primary tumor and spread to other tissues to seed new cancerous growth, causes most cancer deaths.

2 Feb 2023

New center to assist in understanding non-coding cancer genome

The MacMillan Center for the Study of the Non-Coding Cancer Genome (MCSNCG) was officially launched by the New York Genome Center (NYGC) on January 18th, 2023.

19 Jan 2023

The strategy used by metastatic cancer cells to invade the liver identified

The alternative pathway for liver metastasis has been revealed by a team of researchers.

5 Oct 2022

Antibiotics deplete intestinal flora and weaken the immune response

According to a recent study conducted by scientists at Emory University in Atlanta, the administration of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive type of skin cancer, expedited their metastatic bone growth.

12 Sep 2022

Researchers identify key molecular differences between initial and metastatic tumors

Researchers at Johns Hopkins Medicine claim to have discovered significant molecular variations between cancer cells that adhere to an initial tumor and those that spread out to develop distant tumors while researching the fatal form of breast cancer known as triple negative.

9 Aug 2022

Scientists demonstrate a new function of an enzyme that connects to age-related diseases

Aging and age-related diseases present a complex challenge to biomedical researchers.

20 Jul 2022

Study shows how mitochondrial RNA changes enhance invasive growth of cancer cells

The energy centers of cells and mitochondria have their own genetic material and RNA molecules.

1 Jul 2022

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Research reported that the DMDRMR/miR-378a-5p/ DAB2IP axis enhances angiogenesis and sunitinib resistance, suggesting that it could be used for patients with ccRCC.

30 May 2022

Scientist reveals the impact of mitochondria in metastatic prostate cancer

Prostate cancer that has spread to other regions of the body is commonly treated with hormone treatment, but many individuals develop resistance to it, making their disease more aggressive and potentially fatal.

12 May 2022

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and point to new therapy targets.

From University of Pittsburgh 20 Apr 2022

Metastasis News and Research

Using nanoparticles to carry drugs across the blood-brain barrier

Experts reveal the link between necrosis, circulating tumor cells, and cancer metastasis

Reversal of ADAR1 hyper-editing with small molecule inhibitor

Scientists define four cancer molecular subtypes using PDX models

New center to assist in understanding non-coding cancer genome

The strategy used by metastatic cancer cells to invade the liver identified

Antibiotics deplete intestinal flora and weaken the immune response

Researchers identify key molecular differences between initial and metastatic tumors

Scientists demonstrate a new function of an enzyme that connects to age-related diseases

Study shows how mitochondrial RNA changes enhance invasive growth of cancer cells

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Scientist reveals the impact of mitochondria in metastatic prostate cancer

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

Study shows how biodegradable gel helps immune system to keep cancer away

Intracellular microbiota promote cell survival during tumor progression

Research offers new insights for cancer patients to avoid developing metastases

Researchers discover a novel pathway for DNA transfer in the tumor microenvironment

New approach to assess motility and invasive capacity of cancer cells in a tissue section

Study shows that mechanical stress help cancer cells metastasize

Attacking a protein in prostate cancer cells stops the disease spread, research finds

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