Sclerosis News and Research

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Noncoding DNA mutations prevent the brain from amyotrophic lateral sclerosis

When a condition is connected to a genetic mutation, it is generally negative news.

4 Apr 2022

Study reveals why infected individuals cannot get rid of HIV altogether

Thanks to antiretroviral therapy, HIV infection is no longer the life sentence it once was. But despite the effectiveness of drugs to manage and treat the virus, it can never be fully eliminated from the human body, lingering in some cells deep in different human tissues where it goes unnoticed by the immune system.

28 Mar 2022

Researchers develop an antibody as a tool for opening the blood-brain barrier

The brain is composed of billions of neurons-; vulnerable cells that require a protective environment to function properly.

17 Mar 2022

Insight into oligodendrocyte cells could lead to new treatments for neurodegenerative diseases

New research may help scientists locate immature cells in the central nervous system that could shed light on the causes of neurodegenerative diseases like multiple sclerosis-;and autoimmune disease that affects the brain and nervous system-;and allow for the development of better therapeutic treatments.

14 Mar 2022

Protein appears key to the function and survival of brain cells most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

2 Mar 2022

HDO technology found to be effective at silencing problematic genes

T and B lymphocytes, which are part of a group of immune cells commonly called white blood cells, work together to eliminate foreign invaders in the body such as viruses.

1 Mar 2022

Future of AI in Life Science Research

In partnership with the SLAS 2022 exhibition and conference, we speak to Brian O’Sullivan about artificial intelligence and its future within the life sciences sector.

From Society for Laboratory Automation and Screening (SLAS) 1 Mar 2022

Novel molecular pathway shared by ALS and frontotemporal dementia identified

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

1 Mar 2022

Central signaling pathway likely to help reduce the progression of autoimmune disorders

When the immune system fails and assaults the body’s own components, autoimmune disorders develop.

25 Feb 2022

In vivo tracking of unlabeled stem cells using sugars

A Johns Hopkins Medicine scientist who spent 30 years figuring out how to put chemical labels into cells to track their movement in living tissues has found that certain self-renewing stem cells have built-in tracers -; made out of sugars -; that can do the job without added chemical "labels" when injected into mouse brains.

8 Feb 2022

Oligodendrocyte plays major role in the development of multiple sclerosis, says study

A team of international researchers revealed that oligodendrocytes, a kind of central nervous system cell, may play a different function in the progression of MS.

2 Feb 2022

Meat eating, less gut bacteria, more immune cell subsets in the blood linked to multiple sclerosis

Eating more meat, having less of certain bacteria in the gut, and more of certain immune cells in the blood, all link with multiple sclerosis, reports a team of researchers led by UConn Health and Washington University School of Medicine.

27 Jan 2022

Stanford study reveals how ribosomes may contribute to age-related diseases

Aging leads to a decline in cellular fitness and loss of optimal protein function. Many age-related ailments, including Alzheimer's and Parkinson's diseases, are caused by protein aggregation, a result of errors in protein folding.

20 Jan 2022

Increasing the expression of a gene slows Alzheimer’s progression in mice

According to a recent research, enhancing the expression of one gene in cells that help the brain’s neurons, shields neurons in mouse models of Alzheimer’s disease.

13 Jan 2022

Blocking function of blood-clotting protein prevents bone loss from gum disease in mice

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health.

24 Dec 2021

Sclerosis News and Research

Noncoding DNA mutations prevent the brain from amyotrophic lateral sclerosis

Study reveals why infected individuals cannot get rid of HIV altogether

Researchers develop an antibody as a tool for opening the blood-brain barrier

Insight into oligodendrocyte cells could lead to new treatments for neurodegenerative diseases

Protein appears key to the function and survival of brain cells most impacted by glaucoma

HDO technology found to be effective at silencing problematic genes

Future of AI in Life Science Research

Novel molecular pathway shared by ALS and frontotemporal dementia identified

Central signaling pathway likely to help reduce the progression of autoimmune disorders

In vivo tracking of unlabeled stem cells using sugars

Oligodendrocyte plays major role in the development of multiple sclerosis, says study

Meat eating, less gut bacteria, more immune cell subsets in the blood linked to multiple sclerosis

Stanford study reveals how ribosomes may contribute to age-related diseases

Increasing the expression of a gene slows Alzheimer’s progression in mice

Blocking function of blood-clotting protein prevents bone loss from gum disease in mice

First molecular structure of TDP-43 could pave the way for new ALS therapies

Research could help understand DCIR's role in the pathogenesis of autoimmune diseases

Study finds a more sustainable way to develop pharmaceuticals

Study identifies new gene that promotes progression to type 1 diabetes

Apoptosis of mesenchymal stromal cells benefits therapeutic function

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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