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RDP1 gene regulates the production of pollen grains

An international study has discovered a gene in the plant model Arabidopsis that reduces the number of pollen grains.

9 Jun 2020

DNA damage and repair jointly shape mutational signatures

A collaborative project between the Center for Genome Integrity, within the Institute for Basic Science, and the Dundee School of Life Sciences, the EMBL's European Bioinformatics Institute, and the Wellcome Sanger Institute have screened almost 163,000 DNA mutations in 2,700 C. elegans roundworms to shed light on DNA damage.

9 Jun 2020

Study reveals new insight on vaccines and antimicrobials

Bacteria are known to be versatile living organisms capable of colonizing a wide variety of tissues, hosts, or environments inside a host.

9 Jun 2020

Genome rewiring could help explain evolution of multi-cellular organisms

InsideOutBio expert Dr Alan Herbert has explained a pioneering research in a paper recently published online by the Royal Society Open Science journal.

9 Jun 2020

Single-cell-resolution technologies help map brain regions in humans and primates

Using the single-cell-resolution transcriptomics technologies, researchers have performed a large-scale analysis of gene expression in 33 different brain regions of chimpanzees, bonobos, macaques, and humans, and successfully generated a map of the various brain regions with their particular cell structures.

5 Jun 2020

Building blocks of DNA and RNA could have co-existed in the primordial Earth

Scientists have long debated which genetic information carrier - DNA or RNA - started life on Earth, but a new study suggests life could have begun with a bit of both.

4 Jun 2020

Review reveals exceptions to the purported rules of sex chromosome evolution theory

For nearly a century, biologists have modeled the evolution of sex chromosomes--the genetic instructions that primarily determine whether an individual will develop into a male or female (or a certain mating type)--resulting in an impressive theoretical framework.

4 Jun 2020

Scientists uncover a moving target in small cell lung tumors

Lung cancers account for approximately 25 percent of all cancer deaths. Even among those who do not smoke, 1 in 15 men and 1 in 17 women are expected to develop lung cancer in their lifetime, according to the American Cancer Society.

2 Jun 2020

Recombineering technique may overcome barriers in bacterial engineering

Genetic engineering of bacteria has transformed contemporary medicine, from bacterial-based insulin to a deeper insight into infectious diseases.

From Harvard Medical School 1 Jun 2020

Study explores the ways parasites respond to climate change

Warming events are increasing in magnitude and severity, threatening many ecosystems worldwide. As the global temperatures continue to climb, it also raises uncertainties as to the relationship, prevalence, and spread of parasites and disease.

1 Jun 2020

gnomAD Consortium releases first set of discoveries on human genetic variation

For the last eight years, the Genome Aggregation Database Consortium (and its predecessor, the Exome Aggregation Consortium, or ExAC), has been working with geneticists around the world to compile and study more than 125,000 exomes and 15,000 whole genomes from populations around the world.

29 May 2020

Biophysicists shed light on how optogenetic tool works

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state.

29 May 2020

ADHD-associated genetic variants have reduced progressively in human lineage

According to a study published in the Scientific Reports journal, the frequency of genetic variants linked to attention-deficit/hyperactivity disorder (ADHD) has reduced progressively in the evolutionary human lineage from the Palaeolithic to the present day.

29 May 2020