Crystallography News and Research

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New protein design could help in drug discovery for Parkinson’s disease

The neurotransmitter dopamine plays a vital role in everything, starting from motor control to higher cognitive functions, arousal, motivation, sexual gratification, and reinforcement.

12 Jun 2020

Study reveals structure of an activated dopamine receptor

Dopamine, a chemical that sends messages between different parts of the brain and body, plays a key role in a variety of diseases and behaviors by interacting with receptors on cells.

11 Jun 2020

Research suggests new possibility for how glucose transporters operate

Some of the most essential processes on the planet involves water and energy entering and leaving cells.

2 Jun 2020

Biophysicists shed light on how optogenetic tool works

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state.

29 May 2020

Compounds in Brazilian shrub can reduce the virulence of antibiotic-resistant bacteria

Researchers have discovered that the Brazilian peppertree—an invasive, weedy shrub found in Florida—contains specific compounds that lower the virulence of Staphylococcus bacteria that are resistant to antibiotics.

25 May 2020

X-ray experiments reveal antibody to block entry of SARS-CoV-2

As scientists across the globe race to develop a vaccine against SARS-CoV-2, the coronavirus that causes COVID-19, an international team led by Davide Corti at Vir Biotechnology and David Veesler at the University of Washington has been working around the clock on a complementary approach - identifying neutralizing antibodies that could be used as a preventative treatment or as a post-exposure therapy.

20 May 2020

New breakthrough could accelerate drug development

Scientists have successfully developed a new technique to reliably grow crystals of organic soluble molecules from nanoscale droplets, unlocking the potential of accelerated new drug development.

From Newcastle University 11 May 2020

Bacterial Enzyme Activity Could Lead To New Sugar-Based Drugs

Researchers from DTU Biosustain and DTU Bioengineering have elucidated the activity of the enzyme GH109 whose mechanism of activity has been a mystery.

5 May 2020

AI accelerates drug discovery to fight COVID-19

A global race is underway to discover a vaccine, drug, or combination of treatments that can disrupt the SARS-CoV-2 virus, which causes the COVID-19 disease, and prevent widespread deaths.

24 Apr 2020

Biophysicists uncover new features of molecular elevator

Biophysicists from the Moscow Institute of Physics and Technology and the University of Groningen in the Netherlands have visualized a nearly complete transport cycle of the mammalian glutamate transporter homolog from archaea.

21 Apr 2020

UTSW researchers solve structure of key protein involved in muscle contraction

Researchers at UT Southwestern Medical Center have uncovered the detailed shape of a key protein involved in muscle contraction.

16 Apr 2020

New method images proteins in 3D with nanoscale resolution

A research team, which also included scientists from the National Synchrotron Light Source II (NSLS-II), has reported a novel method for imaging proteins in three dimensions (3D) with nanoscale resolution.

16 Apr 2020

Research provides new insights into building blocks of gum disease

Porphyromonas gingivalis is a major bacterial pathogen which leads to periodontitis also known as gum disease. In Japan, 80% of adults aged 35 and over suffer from this disease. What's more, P. gingivalis has also been linked to rheumatoid arthritis, cardiovascular disease, pancreatic cancer, and even Alzheimer's disease.

15 Apr 2020