Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

How Important is the European Ecosystem to Life Sciences Research?

As part of our SLAS Europe 2022 coverage, we speak to Jan Lichtenberg, vice president of SLAS, about the role Europe plays within life sciences research.

From Society for Laboratory Automation and Screening (SLAS) 7 Jul 2022

Online version algorithm helps to detect ramp sequences of RNA, study finds

The significance of detecting and comprehending how variations between tissues and cells influence gene expression without altering the underlying genetic code is discussed in a recent study by University of Kentucky researchers.

1 Jul 2022

Reviving degraded ecosystems with genomics

The monumental global task to restore degraded ecosystems will need to include sophisticated technologies such as environmental DNA monitoring to understand and support the recovery of complex biospheres, international researchers say.

28 Jun 2022

Researchers understand and collect a diverse range of bee genomes

The USDA Agricultural Research Service is directing the “Beenome100” project, which aims to create high-quality maps of the genomes of at least 100 bee species.

27 Jun 2022

Unraveling sex determination in Bursaphelenchus nematodes: A path towards pest-control

The mechanisms underlying sex determination in nematodes, commonly known as roundworms, have not been fully understood.

23 Jun 2022

Scientists restructure the genome of E. coli using fragments extracted from mummy

An international group led by McMaster University researchers, in partnership with the University of Paris Cité, has recognized and reconfigured the first ancient genome of E. coli using fragments derived from a 16th-century mummy’s gallstone.

17 Jun 2022

Computational approach could enable large-scale analyses of tumor-specific total mRNA levels from patient samples

Researchers at The University of Texas MD Anderson Cancer Center have developed a new approach to quantify tumor-specific total mRNA levels from patient tumor samples, which contain both cancer and non-cancer cells.

14 Jun 2022

Cancer biomarkers relying on methylation could forecast tumor type

In cancer management, biomarkers are commonly used to guide treatment decisions and evaluate patient outcomes.

23 May 2022

Genetic options help researchers transmit rust resistance from one plant to another

Stem rust is a major disease in wheat crops around the world, and outbreaks are expected to become more prevalent in upcoming climate change scenarios.

12 May 2022

New software device makes genetic information analysis simpler

Researchers from Texas Biomedical Research Institute and Tulane University have created a new software device that makes analyzing genetic data about a host and its microbiome at the very same time simpler, quicker, and less expensive.

10 May 2022

Enzymes found in capybara gut can promote the application of agroindustrial waste

One option to reduce dependence on oil and other fossil fuels is to transform agroindustrial waste into molecules of interest to society, like biofuels and biochemicals.

10 May 2022

Study identifies novel targets for treating sorafenib-resistant hepatocellular carcinoma

Research headed by Professor Xiujun Cai used the CRISPR/cas9 system to screen the entire genome of hepatocellular carcinoma cells (HepG2) under sorafenib treatment.

25 Apr 2022

Researchers discover a protein that protects the pancreas from self-digestion

The pancreas secretes around a cup of digestive juices per day—a mixture of molecules capable of breaking down the food people consume.

22 Apr 2022

Little-known protein may play a role in frontotemporal lobar degeneration

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

21 Apr 2022

Study identifies new targets for treating sorafenib-resistant hepatocellular carcinoma using CRISPR-Cas9 screening

This study is led by Xiujun Cai (Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine). Professor Xiujun Cai's research team screened the whole genome of hepatocellular carcinoma cells (HepG2) through CRISPR / cas9 system under sorafenib treatment, and screened the dominant gene in sorafenib resistance.

20 Apr 2022

Researchers uncover a treasure trove of new data about RNA viruses

Ocean water samples collected around the world have yielded a treasure trove of new data about RNA viruses, expanding ecological research possibilities and reshaping our understanding of how these small but significant submicroscopic particles evolved.

8 Apr 2022

Lifebit; Making Biomedical Data Accessible

In this interview, we speak to Dr. Maria Chatzou Dunford, CEO of Lifebit, about their technology and how it helps scientists to make better use of their data.

From Lifebit 1 Apr 2022

Scientists develop a novel approach, enabling spatial mapping of single-cell data within tissue

Scientists develop a new approach that efficiently integrates information from parallel gene-expression profiling methods at single-cell resolution.

23 Mar 2022

Researchers use urinary proteomics to detect abnormalities inside the body

Dr Jun Qin, a proteomics expert from the State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, and Dr Zhongde Zhang from The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, worked in the front line of compacting COVID-19 disease.