RNA Sequencing News and Research

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Bone growth protein may help treat newborns with rare genetic lung condition

When babies are born with alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV), their skin starts to turn blue from the under-oxygenated blood in their systems.

22 Apr 2022

New research shows significant variations in B-cells in women with PPD

Jerry Guintivano, PhD, of the University of North Carolina School of Medicine, led an exclusive transcriptome-wide association research that showed substantial changes in B-cells in women with postpartum depression, with pathway observations indicating modified B-cell activation and insulin resistance.

19 Apr 2022

16 distinct cell populations identified in a key brain region for substance use disorders

In a work of systematic biology that advances the field, University of Alabama at Birmingham researchers have identified 16 distinct cell populations in a complex area of the midbrain called the ventral tegmental area, or VTA.

18 Apr 2022

Spatial maps offer insights into the battle between melanoma cells and immune cells

Melanoma is a somewhat unusual cancer-;one that blooms before our very eyes, often on sun-exposed skin, and can quickly become deadly as it turns our own skin against us and spreads to other organs.

From Harvard Medical School 15 Apr 2022

Researchers develop a universal AI algorithm for deep clean-up of single cell genomic data

A single cell’s genome or transcriptome can reveal considerably more data about its place in biological systems than sequencing a full batch of cells, just as interviewing a single person about their health will provide specialized, personalized information hard to obtain from a big poll.

11 Apr 2022

Study reveals how plants activate their immune system to prevent infections caused by rain

While rain is essential for the survival of plants, it also contains bacteria and other pathogens which can cause them harm. So how do plants protect themselves from this threat?

7 Apr 2022

Single-cell RNA sequencing reveals temporal patterning network in Drosophila medulla neuroblasts

The nervous system is made up of diverse cells that arise from progenitors in a specific time-dependent pattern.

6 Apr 2022

Mice study sheds light on why tissues often fail to regenerate from muscle-loss injuries

Tissues often fail to regenerate from traumatic muscle-loss injuries such as gunshot wounds and car accidents, and new research in mice from the University of Michigan sheds light on why.

6 Apr 2022

A critical subset of supporting cells may lie at the origins of scleroderma

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022

Scientists develop a novel approach, enabling spatial mapping of single-cell data within tissue

Scientists develop a new approach that efficiently integrates information from parallel gene-expression profiling methods at single-cell resolution.

23 Mar 2022

New map tracks cellular trajectories across mouse embryogenensis

Scientists have mapped out the key molecular changes that orchestrate how embryonic mouse cells differentiate into the diverse cell types that will ultimately form all the different tissues and organs of the adult animal.

15 Mar 2022

T cells sometimes remain in the skin for years, research finds

Human immune cells not only circulate in the blood, but can also occupy certain tissues and sometimes remain there for years.

8 Mar 2022

Intestinal cell changes are driven by the BMP signaling pathway, study finds

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes.

2 Mar 2022

Men and women do have immune cell differences, study says

Researchers at the La Jolla Institute for Immunology have uncovered novel genes associated with the risk of autoimmune disorders in the CD4+ “helper” T cell subset.

2 Mar 2022

Why is it Important to have Diverse Genomics Data in Science?

In this interview, we speak to Dr. Santiago Miriuka, CEO of MultiplAI Health, about the importance of having diverse genomics data in research.

From MultiplAI Health 17 Feb 2022

New and unconventional nuclear function for oncogenic microRNA discovered

microRNAs (miRNA), non-coding RNA molecules, are widely known for regulating mRNA stability and translation. miR-10b has been increasingly implicated in the pathogenesis of gliomas, cancers of the brain.

16 Feb 2022

MIT researchers create a new cerebrovasculature atlas

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

16 Feb 2022

Researchers discover DisCo for effective processing of samples with fewer cells

Single-cell RNA sequencing is an approach that lets researchers to study the gene expression in an individual cell within a mixed population.

16 Feb 2022

Single-cell sequencing technique helps to examine early SARS-CoV-2 infection

In the early days of SARS-CoV-2 infection in the lungs, what happens at the single-cell level?

14 Feb 2022

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

An international team led by the Case Western Reserve University School of Medicine has discovered novel properties of the protein Gasdermin B that promotes repair of cells lining the gastrointestinal tract in people with chronic inflammatory disorders like Crohn's disease and ulcerative colitis.

8 Feb 2022

RNA Sequencing News and Research

Bone growth protein may help treat newborns with rare genetic lung condition

New research shows significant variations in B-cells in women with PPD

16 distinct cell populations identified in a key brain region for substance use disorders

Spatial maps offer insights into the battle between melanoma cells and immune cells

Researchers develop a universal AI algorithm for deep clean-up of single cell genomic data

Study reveals how plants activate their immune system to prevent infections caused by rain

Single-cell RNA sequencing reveals temporal patterning network in Drosophila medulla neuroblasts

Mice study sheds light on why tissues often fail to regenerate from muscle-loss injuries

A critical subset of supporting cells may lie at the origins of scleroderma

Scientists develop a novel approach, enabling spatial mapping of single-cell data within tissue

New map tracks cellular trajectories across mouse embryogenensis

T cells sometimes remain in the skin for years, research finds

Intestinal cell changes are driven by the BMP signaling pathway, study finds

Men and women do have immune cell differences, study says

Why is it Important to have Diverse Genomics Data in Science?

New and unconventional nuclear function for oncogenic microRNA discovered

MIT researchers create a new cerebrovasculature atlas

Researchers discover DisCo for effective processing of samples with fewer cells

Single-cell sequencing technique helps to examine early SARS-CoV-2 infection

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

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