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New technique controls gene activity without altering the DNA sequence of the genome

By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical "off switches" that silence them.

7 Mar 2022

Researchers develop new method to detect the role of enigmatic gene sequences

Karolinska Institute researchers have recently developed new high-precision techniques for determining the role of these noncoding sequences.

7 Mar 2022

CNIC study uncovers a nuclear import mechanism essential for organ growth and development

Scientists at the Centro Nacional de Investigaciones Cardiovasculares have identified a nuclear import mechanism essential for organ growth and development. Manipulation of this mechanism has potential applications in the control of organ growth and organ regeneration.

4 Mar 2022

Researchers find an epigenetic adaptation showing resistance to targeted therapy in T cell leukemia

Although gene mutations can result in drug resistance, scientists in the Perelman School of Medicine at the University of Pennsylvania have found a vital, non-genetic version that could also boost resistance to targeted treatment in T cell leukemia, which is a kind of blood cell cancer.

3 Mar 2022

Scientists discover a human receptor protein capable of identifying individual amino acids

Researchers have found that a human receptor protein can identify individual amino acids in just the similar way that bacteria do.

3 Mar 2022

Intestinal cell changes are driven by the BMP signaling pathway, study finds

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes.

2 Mar 2022

Men and women do have immune cell differences, study says

Researchers at the La Jolla Institute for Immunology have uncovered novel genes associated with the risk of autoimmune disorders in the CD4+ “helper” T cell subset.

2 Mar 2022

Researchers discover a new epigenetic mark in small freshwater animals

Your DNA holds the blueprint to build your body, but it's a living document: Adjustments to the design can be made by epigenetic marks.

1 Mar 2022

Genetic analysis reveals markers for predicting seed oil quality in Russian sunflower

Researchers from Skoltech and Pustovoit All-Russian Research Institute of Oil Crops performed a genetic analysis of Russian sunflower lines and identified genetic markers that can help to predict the composition of tocopherols, one of the key attributes of oil quality.

1 Mar 2022

HDO technology found to be effective at silencing problematic genes

T and B lymphocytes, which are part of a group of immune cells commonly called white blood cells, work together to eliminate foreign invaders in the body such as viruses.

1 Mar 2022

Novel molecular pathway shared by ALS and frontotemporal dementia identified

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

1 Mar 2022

Study provides first genetic evidence of demographic changes among hunter-gatherer populations

A new analysis of ancient human DNA demonstrates that people moved and chose their reproductive partners along complex social networks that stretched across large swathes of Africa between 80,000 and 20,000 years ago, according to a study co-led by Yale anthropologist Jessica Thompson.

28 Feb 2022

Looking at protein activity gives a complete picture of leukemia's weaknesses

Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows.

28 Feb 2022

Macrophages restore normal functions when transported back to the body, says research

New research shows that some immune cells could reinstate their regular functions when they are introduced back into the body.

28 Feb 2022

Chlamydia and HPV co-infection causes a unique cellular reprogramming, study shows

Infections with several pathogens simultaneously increase the risk of cervical cancer—these results from a study conducted on artificial 3D tissue models.

25 Feb 2022

Researchers create a regulatory map of zebrafish genome

The zebrafish is an important model organism for studying things like genetic diseases. A regulatory map of its genome has been successfully created using high-throughput experiments and AI methods, a team led by Uwe Ohler now reports in Cell Genomics and Nature Machine Intelligence.

25 Feb 2022

Genetics serves a vital role in the way human bodies respond to vaccination and boosters, says study

According to a new study headed by University of Michigan researchers, genetics serve a vital role in the way human bodies respond to vaccinations and booster shots.

25 Feb 2022

A cryptic molecule can awaken killer viruses from their slumber

Some gut bacteria have a spooky superpower: they can reanimate dormant viruses lurking within other microbes.

24 Feb 2022

New technique uses microscopic magnetic particles to remotely activate brain cells

Scientists at UCL have developed a new technique that uses microscopic magnetic particles to remotely activate brain cells; researchers say the discovery in rats could potentially lead to the development of a new class of non-invasive therapies for neurological disorders.

From University College London 24 Feb 2022

Scientists study the distant connection between Archaea and Bacteria

Researchers have discovered more evidence to support the idea that the two primary domains of life, Archaea and Bacteria, are detached by a long phylogenetic tree branch.

24 Feb 2022

Genes News and Research

New technique controls gene activity without altering the DNA sequence of the genome

Researchers develop new method to detect the role of enigmatic gene sequences

CNIC study uncovers a nuclear import mechanism essential for organ growth and development

Researchers find an epigenetic adaptation showing resistance to targeted therapy in T cell leukemia

Scientists discover a human receptor protein capable of identifying individual amino acids

Intestinal cell changes are driven by the BMP signaling pathway, study finds

Men and women do have immune cell differences, study says

Researchers discover a new epigenetic mark in small freshwater animals

Genetic analysis reveals markers for predicting seed oil quality in Russian sunflower

HDO technology found to be effective at silencing problematic genes

Novel molecular pathway shared by ALS and frontotemporal dementia identified

Study provides first genetic evidence of demographic changes among hunter-gatherer populations

Looking at protein activity gives a complete picture of leukemia's weaknesses

Macrophages restore normal functions when transported back to the body, says research

Chlamydia and HPV co-infection causes a unique cellular reprogramming, study shows

Researchers create a regulatory map of zebrafish genome

Genetics serves a vital role in the way human bodies respond to vaccination and boosters, says study

A cryptic molecule can awaken killer viruses from their slumber

New technique uses microscopic magnetic particles to remotely activate brain cells

Scientists study the distant connection between Archaea and Bacteria

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