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Novel method maps all gene expression patterns to a single reference embryo

Years of work by Trinity College Dublin developmental biologists in collaboration with colleagues at the University of Edinburgh’s MRC Human Genetics Unit has resulted in an unparalleled resource that will help researchers assess how key genes control the differentiation of tissues and organs in developing embryos.

23 Aug 2022

Researchers identify key molecular differences between initial and metastatic tumors

Researchers at Johns Hopkins Medicine claim to have discovered significant molecular variations between cancer cells that adhere to an initial tumor and those that spread out to develop distant tumors while researching the fatal form of breast cancer known as triple negative.

9 Aug 2022

Researchers discover cancer cells move to sweet spot conditions, likely to enable stronger traction

Cancer cells can be drawn to certain mechanical “sweet spot” conditions, according to a global team of researchers headed by University of Minnesota Twin Cities engineers.

14 Jul 2022

New system offers a potential solution for wide-scale stem cell production

Researchers have developed a unique 3D printed system for harvesting stem cells from bioreactors, offering the potential for high quality, wide-scale production of stem cells in Australia at a lower cost.

17 Jun 2022

Preclinical study describes a promising approach to regenerate damaged cartilage

Osteoarthritis – a painful condition that results from the deterioration of the cartilage in our joints – affects millions of people worldwide.

6 Jun 2022

Vienna researchers aim to solve a great mystery of human evolution

Using the latest scientific methods, Tom Higham and Katerina Douka from the University of Vienna want to solve a great mystery of human evolution: Why are we the only humans left? Higham and Douka were the first ones to find a first-generation offspring of two different types of human. They continuously publish new results in high impact journals, most recently in Science Advances.

3 Jun 2022

Researchers create human cornea-on-a-chip to check the therapeutic effect of MSC exosomes on corneal disorders

Ophthalmologists and researchers have been looking into mesenchymal stem cells (MSCs) with regenerative and differentiation capacities as a potential therapy option for corneal disorders.

30 May 2022

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

From National University of Singapore (NUS) 27 May 2022

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Small interfering RNAs, or siRNAs, have the potential to cure tumors by targeting knocking down oncogenes that drive tumor development while avoiding the damage associated with chemotherapy.

25 May 2022

Researchers devise a new treatment approach to cure aggressive brain tumors

Glioblastomas (GBMs) are cancerous tumors of the brain and spinal cord that are incredibly aggressive.

23 May 2022

Researchers discover protein that enhances muscle mass

Humans are not just pumping iron in the gym, or not just oxygenating muscle cells, which keeps those muscles healthy, powerful, and developing—a process known as hypertrophy—that is defined as an increase in muscle mass, caused by an increase in muscle cell size.

29 Apr 2022

National DNA Day 2022: an interview with Professor Matthew Cobb

To celebrate National DNA Day 2022, we spoke to science communicator Professor Matthew Cobb.

From The University of Manchester 25 Apr 2022

Bone growth protein may help treat newborns with rare genetic lung condition

When babies are born with alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV), their skin starts to turn blue from the under-oxygenated blood in their systems.

22 Apr 2022

Rutgers researchers team up to develop and produce lab-grown, structured meats

A pair of Rutgers researchers are teaming up to combat climate change and worldwide hunger at the same time.

From Rutgers University 21 Apr 2022

Stem cell-mediated gene therapy technique helps to boost bone regeneration

Mesenchymal stem cell-derived exosomes (MSC-Exo) have gained a lot of attention due to their “cell-free” treatments.

20 Apr 2022

Double-stranded RNA provoke bone loss during periodontitis

Researchers from Tokyo University of Agriculture and Technology have made a novel revelation about the processes of bone loss in gum disease (periodontitis).

19 Apr 2022

Research could open up pathways for 3D printing any kind of organ at any time

Human organ transplants offer a crucial lifeline to people with serious illnesses, but there are too few organs to go around: in the U.S. alone, there are more than 112,000 people currently waiting for transplants.

15 Apr 2022

Bioprinting bone along with two growth factor encoding genes improves bone repair

Given enough time and energy, the body will heal, but when doctors or engineers intervene, the processes do not always proceed as planned because chemicals that control and facilitate the healing process are missing.

From Penn State University 13 Apr 2022

Curcumin released from magnetic hydrogels can aid in vascular regeneration

A finding by UC Riverside bioengineers could hasten development of lab-grown blood vessels and other tissues to replace and regenerate damaged tissues in human patients.

7 Apr 2022

Novel method to obtain genomic data shows potential success

Researchers at the University of Otago have developed a novel technique for acquiring ancient genomic data without causing damage to the source material, opening up new possibilities for museum and archaeological collections around the world.