Cell Biology

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New 3D in vitro model reveals the origins of human spine

The spinal column is the central supporting structure of the skeleton in all vertebrates. Not only does it provide a place for muscles to attach, it also protects the spinal cord and nerve roots. Defects in its development are known to cause rare hereditary diseases.

28 Apr 2022

Understanding the regulation of intramembrane proteases across the tree of life

Working with tiny bacteria, Michigan State University researchers led by Lee Kroos have made a discovery that could have big implications for biology.

27 Apr 2022

Genetic variations in key mitochondrial enzyme associated with age-related mobility changes

Age-related changes in strength and mobility may depend on genetic variations in a critical mitochondrial enzyme, suggests a study published today in eLife.

27 Apr 2022

Regulatory framework of stem cell-based therapy in China

Clinical researches of stem cell-based therapies are highly active in China, while it was arduous to determine the most effective way of clinical translation of those advanced therapies.

25 Apr 2022

CD8 + Tscm may has protective immunity to hepatitis C virus infection

The dysfunction of memory CD8 + T cell can not be reverted by successful clearance of hepatitis C virus (HCV) after direct-acting antivirals (DAA) therapy, increasing the risk of reinfection with HCV.

25 Apr 2022

Safety, feasibility of intranasal human milk as stem cell therapy for preterm infants with intraventricular hemorrhage

A new study demonstrates that intranasal human milk is a safe and feasible intervention for intraventricular hemorrhage, a serious cause of morbidity in preterm infants.

25 Apr 2022

Researchers shed light on development and treatment of brain diseases

It is highly regulated what goes into the brain and what does not. The phagocytes that encapsulate the blood arteries in the brain and maintain the blood-brain barrier have been examined by researchers at the University of Freiburg’s Faculty of Medicine.

25 Apr 2022

Study shows how potential target helps to treat lung disease induced by air pollution

According to research published in eLife, scientists have discovered a mechanism that explains how small air pollution particles may cause lung cancer.

25 Apr 2022

SARS-CoV-2 can directly infect a specialized type of kidney cell

The virus that causes COVID-19, SARS-CoV-2, can directly infect a specialized type of kidney cell.

22 Apr 2022

Bone growth protein may help treat newborns with rare genetic lung condition

When babies are born with alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV), their skin starts to turn blue from the under-oxygenated blood in their systems.

22 Apr 2022

Astrocyte abnormalities may play a pivotal role in causing ASD symptoms

Abnormalities in a type of brain cell called astrocytes may play a pivotal role in causing some behavioral symptoms of autism spectrum disorders, according to a preclinical study by Weill Cornell Medicine investigators.

22 Apr 2022

Researchers discover a protein that protects the pancreas from self-digestion

The pancreas secretes around a cup of digestive juices per day—a mixture of molecules capable of breaking down the food people consume.

22 Apr 2022

Manipulating immune cells to suppress the growth of some solid tumors

Cancer researchers at the Case Western Reserve University School of Medicine say they have successfully suppressed the growth of some solid tumors in research models by manipulating immune cells known as a macrophages.

21 Apr 2022

Extra copies of DNA explain insensitivity to chemotherapy in germ cell cancer

Extra copies of a piece of DNA partly explain insensitivity to chemotherapy in germ cell cancer, a new study shows.

21 Apr 2022

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

All modern organisms fall into two classes, eukaryotes and prokaryotes. Eukaryotes (from the Greek meaning "true kernel") have a cell nucleus that harbors most of the cell's genetic information and includes organisms such as humans, plants and fungi.

20 Apr 2022

Research associates autophagy and age-related nervous system degradation

The in-built mechanism of recycling dead or poisonous material to preserve the health of human cells is critical to general health.

20 Apr 2022

Scientists reveal the origins and provide a detailed ID card of pancreatic endocrine stem cells

The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes.

20 Apr 2022

Microglia regulate the intrinsic excitability of neuronal subtypes differently

A new study reports that immune cell responses to bacteria affect the intrinsic excitability of rat neuronal subtypes differently.

20 Apr 2022

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and point to new therapy targets.

From University of Pittsburgh 20 Apr 2022

Stem cell-mediated gene therapy technique helps to boost bone regeneration

Mesenchymal stem cell-derived exosomes (MSC-Exo) have gained a lot of attention due to their “cell-free” treatments.

20 Apr 2022

Cell Biology

New 3D in vitro model reveals the origins of human spine

Understanding the regulation of intramembrane proteases across the tree of life

Genetic variations in key mitochondrial enzyme associated with age-related mobility changes

Regulatory framework of stem cell-based therapy in China

CD8 + Tscm may has protective immunity to hepatitis C virus infection

Safety, feasibility of intranasal human milk as stem cell therapy for preterm infants with intraventricular hemorrhage

Researchers shed light on development and treatment of brain diseases

Study shows how potential target helps to treat lung disease induced by air pollution

SARS-CoV-2 can directly infect a specialized type of kidney cell

Bone growth protein may help treat newborns with rare genetic lung condition

Astrocyte abnormalities may play a pivotal role in causing ASD symptoms

Researchers discover a protein that protects the pancreas from self-digestion

Manipulating immune cells to suppress the growth of some solid tumors

Extra copies of DNA explain insensitivity to chemotherapy in germ cell cancer

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

Research associates autophagy and age-related nervous system degradation

Scientists reveal the origins and provide a detailed ID card of pancreatic endocrine stem cells

Microglia regulate the intrinsic excitability of neuronal subtypes differently

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

Stem cell-mediated gene therapy technique helps to boost bone regeneration

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