Genomics

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Targeting MAPK4 in triple-negative breast cancer may lead to improved treatments

Scientific evidence supporting the involvement of the enzyme MAPK4 in cancer growth and resistance to certain therapies has been growing quickly.

12 Jan 2022

Study shows how skin cells act as a firewall against cancer

A study published today in Cell Reports reveals important insights into the molecular mechanisms that underpin the body's natural defenses against the development of skin cancer.

12 Jan 2022

Researchers map the cellular landscape in diabetic foot ulcers

Diabetic foot ulcerations – open sores or wounds that refuse to heal – are a devastating complication affecting more than 15 percent of people with diabetes and resulting in more than 70,000 lower extremity amputations per year in the United States alone.

11 Jan 2022

New gene determines whether ultraviolet iridescence shows up in butterfly wings

A team of researchers at the George Washington University has identified a gene that determines whether ultraviolet iridescence shows up in the wings of butterflies.

11 Jan 2022

Genetic signature of hybrid incompatibilities can be caused by ecology, research shows

You're likely familiar with the idea of the sterile mule: a hybrid animal born of a horse and a donkey that is unable to breed.

11 Jan 2022

Fingerprints are influenced by the limb development genes, says study

Researchers found that the shape of fingerprints is determined by limb development genes instead of skin patterning genes, in the most thorough analysis to date.

10 Jan 2022

Sampling zoo air could help collect enough DNA to identify the animals nearby

The air in a zoo is full of smells, from the fish used for feed to the manure from the grazing herbivores, but now we know it is also full of DNA from the animals living there.

7 Jan 2022

Experts develop Immuno-CRISPR assay to detect kidney transplant complications

Doctors monitor kidney transplant recipients for signs of rejection in several ways, including biopsy.

7 Jan 2022

Research shows how bacteria silence potentially deadly genes

Humans are all made of collections of cells, where each cell contains instructions in the DNA to become another cell.

7 Jan 2022

Experts introduce new gene therapy approach for muscle weakness

Experts at Children’s National Hospital have created a new pre-clinical gene therapy for the rare condition limb-girdle muscular dystrophy (LGMD) 2B.

7 Jan 2022

Novel delivery system for genome editing in vascular endothelial cells developed

The laboratory of Youyang Zhao developed a novel nanoparticle to deliver genome editing technology, such as CRISPR/Cas9, to endothelial cells, which line blood vessel walls.

7 Jan 2022

Researchers use genomics to dig deeper into lychee’s history

Lychees, prickly on the exterior but sweet inside are loved for their iconic pink shells and pearly, fragrance.

7 Jan 2022

Research analyzes horizontal gene transfer between viruses and eukaryotes

The level at which viruses can pick up genes from their hosts to hone their infection process is illustrated by the first analysis of viral horizontal gene transfer.

7 Jan 2022

Researchers fine-tune an additional system for more efficient gene editing

Over the past decade, the CRISPR genome-editing system has revolutionized molecular biology, giving scientists the ability to alter genes inside living cells for research or medical applications. Now, researchers at Gladstone Institutes have fine-tuned an additional system for more efficient gene editing, using molecules called retrons.

6 Jan 2022

Genetic material found in blood samples can detect women at risk of pre-eclampsia

A study of pregnant women's blood RNA has found specific molecular profiles that identify women at risk of pre-eclampsia. These insights can identify complications before a woman experiences symptoms.

6 Jan 2022

A folic acid-like drug changes a DNA process within brain tumors

A folic acid-like drug, L-methylfolate, when administered alongside the standard therapy for patients with recurrent glioblastoma, changed aDNA process within their brain tumors, according to results from a phase 1 clinical trial.

From Vanderbilt University 6 Jan 2022

Olfactory receptor gene may drive breast cancer metastasis to the brain

An olfactory receptor gene that aids in the sense of smell may also play a role in the metastasis of breast cancer to the brain, bones and lung, researchers from Massachusetts General Hospital have found.

4 Jan 2022

Study reveals a tug-of-war between genes inherited from the father and the mother

Cambridge scientists have identified a key signal that the fetus uses to control its supply of nutrients from the placenta, revealing a tug-of-war between genes inherited from the father and from the mother. The study, carried out in mice, could help explain why some babies grow poorly in the womb.

28 Dec 2021

Genes key to microbial colonization of plant roots discovered

Some microbes can form thin films called biofilms. These biofilms give them an advantage over other microbes by protecting them from stresses such as a lack of nutrients or the presence of harmful substances in the environment.

24 Dec 2021

Scientists discover hotspots in the 'dark genome' associated with schizophrenia and bipolar disorder

Scientists investigating the DNA outside our genes - the 'dark genome' - have discovered recently evolved regions that code for proteins associated with schizophrenia and bipolar disorder.

24 Dec 2021

Genomics

Targeting MAPK4 in triple-negative breast cancer may lead to improved treatments

Study shows how skin cells act as a firewall against cancer

Researchers map the cellular landscape in diabetic foot ulcers

New gene determines whether ultraviolet iridescence shows up in butterfly wings

Genetic signature of hybrid incompatibilities can be caused by ecology, research shows

Fingerprints are influenced by the limb development genes, says study

Sampling zoo air could help collect enough DNA to identify the animals nearby

Experts develop Immuno-CRISPR assay to detect kidney transplant complications

Research shows how bacteria silence potentially deadly genes

Experts introduce new gene therapy approach for muscle weakness

Novel delivery system for genome editing in vascular endothelial cells developed

Researchers use genomics to dig deeper into lychee’s history

Research analyzes horizontal gene transfer between viruses and eukaryotes

Researchers fine-tune an additional system for more efficient gene editing

Genetic material found in blood samples can detect women at risk of pre-eclampsia

A folic acid-like drug changes a DNA process within brain tumors

Olfactory receptor gene may drive breast cancer metastasis to the brain

Study reveals a tug-of-war between genes inherited from the father and the mother

Genes key to microbial colonization of plant roots discovered

Scientists discover hotspots in the 'dark genome' associated with schizophrenia and bipolar disorder

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