Genomics

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New scalable genetic control system to restrain disease-spreading mosquitoes

Leveraging advancements in CRISPR-based genetic engineering, researchers at the University of California San Diego have created a new system that restrains populations of mosquitoes that infect millions each year with debilitating diseases.

From UC San Diego 13 Sep 2021

Smoking-related DNA methylation patterns explain the variation in BMI between individuals

Smoking-related DNA methylation patterns explain around a fifth of the variation in body mass index (BMI) between individuals, according to a study publishing September 9th in the open-access journal PLOS Genetics, led by Carmen Amador at the University of Edinburgh.

13 Sep 2021

Viruses buried in marsupials' DNA may help protect against future infections

Fossils of ancient viruses are preserved in the genomes of all animals, including humans, and have long been regarded as junk DNA. But are they truly junk, or do they actually serve a useful purpose?

From The University of New South Wales (UNSW) 9 Sep 2021

Functional genomics can assist in molecular breeding of maize, finds study

For centuries, the vast physical diversity of maize, the most popular cereal grain crop globally, has fascinated biologists and plant breeders alike.

9 Sep 2021

Study unearths previously unknown role of CTCF, the transcription regulator

Researchers discovered evidence that CTCF governs chromatin accessibility, the mechanism of opening tightly spooled DNA facilitating gene expression.

9 Sep 2021

New framework to evaluate the risks of antibiotic resistance genes

Scientists have created a useful framework to assess the risks of antibiotic resistance genes (ARGs).

8 Sep 2021

Study details replication and immune evasion of Delta SARS-CoV-2 variant

According to scientists, the Delta variant of SARS-CoV-2 has likely spread through its capability to avoid neutralizing antibodies and its heightened infectivity.

8 Sep 2021

Polygenic risk scores are no better in predicting disease, says study

Scientists went through the records of more than 8,000 schizophrenia patients and identified a tool used for assessing an individual’s genetic risk for a disease.

8 Sep 2021

Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

A compact CRISPR-Cas system, known as CasMINI, can be employed for gene-therapy and cell-engineering applications as it is easier to deliver into cells.

7 Sep 2021

Drug-resistant Salmonella serovar Enteritidis genome sequenced by experts

Scientists sequenced the genome of a virulent Salmonella Enteritidis strain and discovered that it was both antibiotic-resistant and could affect people.

7 Sep 2021

Study provides deep insights into the association between genes and diseases

Scientists examined genomic data from more than 30,000 individuals and unraveled thousands of new regulatory regions that regulate disease-linked genes.

7 Sep 2021

Plant bulbs harboring lethal pathogen make the perfect lab for evolving drug-resistant strains

Just when we thought it was safe to go to the local garden center, researchers from Japan have discovered that fungicide-resistant strains of a nasty pathogen have been getting up to no good among the tulip bulbs.

6 Sep 2021

Miniature CRISPR-Cas system expands applicability and implications further

For the first time, Stanford researchers have miniaturized CRISPR for mammalian gene editing, which magnifies the scope of CRISPR technology.

3 Sep 2021

Growing wheat endowed with biological nitrification inhibition raises productivity, quality

An international collaboration has discovered and transferred to elite wheat varieties a wild-grass chromosome segment that causes roots to secrete natural inhibitors of nitrification, offering a way to dial back on heavy fertilizer use for wheat and to reduce the crop's nitrogen leakage into waterways and air, while maintaining or raising its productivity and grain quality, says a new report in the Proceedings of the National Academy of Sciences of the United States of America.

3 Sep 2021