Genomics

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Study unravels factors involved in risiRNA generation

A team of scientists disclosed the nucleolar RNA interference based on Caenorhabditis elegans (C. elegans) as a model organism.

1 Oct 2021

Study sheds light on the genetic toolkit used during evolution to create different extremities

A sophisticated system guides the development of our limbs. Researchers at University of Basel have shed new light on the genetic toolkit used during evolution to create a range of different extremities such as fins, wings, hooves, toes and fingers.

30 Sep 2021

Mapping the genome of Eurasian spruce bark beetle reveals new insights

Researchers have successfully mapped the entire genome of the Eurasian spruce bark beetle. The breakthrough paves the way for new research into bark beetles and better prospects for effective pest control of a species that can destroy more than 100 million cubic meters of spruce forest during a single year in Europe and Asia.

30 Sep 2021

Gene expression changes help understand the mechanism behind noise-induced hearing loss

A growing number of people are suffering from hearing loss due to exposure to loud noises from heavy machinery, concerts, or explosions. As a result, scientists have been working to understand the mechanism behind how the damage to hearing actually occurs.

30 Sep 2021

New partnership reveals the genetic secrets hidden in 7,000 grapevines

A new partnership revealing the genetic secrets hidden in 7,000 grapevines are yielding clues that could make the U.S. grape industry more resilient and deliver new kinds of grapes to benefit growers and consumers alike.

30 Sep 2021

Supercoiling and looping can transmit mechanical stress along the DNA backbone, shows study

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are known to influence every aspect of DNA activity, but how this happens has not been clear.

28 Sep 2021

Study employs machine learning to predict outcomes in agriculture

Recent research emphasizes that machine learning can identify “genes of importance” that support crops to grow with reduced fertilizer.

From New York University (NYU) 28 Sep 2021

Researchers examine the deep past of human population dynamics

The current year marks the 20th anniversary of human genome sequencing. To mark this event, scientists headed by Professor Qiaomei Fu from the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences reviewed the current progress in the area of ancient DNA (aDNA)—DNA acquired from the remains of past organisms.

28 Sep 2021

Research provides new insights into growth hormone receptor gene's evolutionary history

A new study delves into the evolution and function of the human growth hormone receptor gene, and asks what forces in humanity's past may have driven changes to this vital piece of DNA.

27 Sep 2021

Remnants of organic molecules and chromatin found in nuclei of ancient dinosaur cells

A team of scientists from the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences and from the Shandong Tianyu Museum of Nature (STM) has isolated exquisitely preserved cartilage cells in a 125-million-year-old dinosaur from Northeast China that contain nuclei with remnants of organic molecules and chromatin.

27 Sep 2021

Study adds two new genetic variants to the list of glutamate receptor mutations

Researchers from Northwestern Medicine distinguished different variants of the gene GRIK2 that induces nonsyndromic neurodevelopmental disorder (NDD).

27 Sep 2021

Tumor suppressor protein binding to RNA also binds DNA, says study

Scientists from the Medical University of South Carolina earlier displayed how hnRNP E1 attaches to metastatic-linked RNAs to prevent their translation.

27 Sep 2021

Exploring cell and gene based therapies for Parkinson’s disease

After several decades of pre-clinical development, cell- and gene-based therapies for Parkinson's disease (PD) are now actively being explored. In this special supplement to the Journal of Parkinson's Disease on "Repairing the Parkinsonian Brain," experts highlight some of the current strategies being pursued to restore lost function and replace what is lost in the PD brain, with special emphasis on the challenges associated with translating advanced therapeutic approaches into pioneering clinical trials.

24 Sep 2021

NIH to renew grants to continue building the ClinGen resource

In an effort to continue building the Clinical Genome Resource, the National Institutes of Health will be renewing three awards amounting to $73.2 million over five years.

From National Human Genome Research Institute (NHGRI) 24 Sep 2021

How do genetic variants influence the expression of genes in the blood?

Researchers are now pursuing intensive research on the genetic causes of traits and diseases, with over 250,000 such links known currently.

24 Sep 2021

How does the KLF4 transcription factor influence gene expression?

Scientists have led a research group to identify a mechanism using which transcription factor KLF4 can influence gene expression.

24 Sep 2021

Naturally occurring protein that blocks inflammatory response linked to better stroke recovery in mice

A naturally occurring protein that blocks an inflammatory immune response was associated with better stroke recovery in a study conducted in mice, according to preliminary research to be presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2021.

23 Sep 2021