Genomics

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Researchers provide novel treatment target for common skin condition

Recent research indicates that a familiar inflammatory skin condition might arise due to inadequately regulated sex hormones.

23 Sep 2021

Genetic and epigenetic origin of pediatric liver cancer uncovered

Researchers at Hiroshima University have analyzed the molecular findings of almost 160 pediatric liver cancer cases and discovered molecular markers that should help to understand and treat the considerable variation in prognoses.

22 Sep 2021

Researchers seek to point a way toward a unified theory for DNA folding

At more than 2 meters long, the human DNA molecule uses intricate folding patterns to fit into cells while locally unfolding to express genes. Such phenomena, however, are difficult to measure in experiments, and theoretical frameworks explaining them continue to be at odds with one another.

22 Sep 2021

Study finds greater facial asymmetry in parents of autistic individuals

Recent research in Western Australia employs high-tech 3D facial scans to provide better knowledge of the genetic causes of autism.

21 Sep 2021

Research provides novel insight into plant chloroplasts and proteins within

A recent study provides insight into plant chloroplasts and the proteins inside them.

17 Sep 2021

Researchers describe investigations into an enigmatic group of coral-infecting microbes

In a Pearls article publishing September 16th in the open-access journal PLOS Pathogens, Patrick Keeling and colleagues at the University of British Columbia in Canada describe investigations into an enigmatic group of coral-infecting microbes.

17 Sep 2021

Hundreds of mutated tumor suppressor genes can help cancer cells evade the immune system

Hundreds of cancer-linked genes play a different role in causing disease than scientists had expected.

17 Sep 2021

New genetic classifier can predict the sensitivity of chemotherapy for breast cancer

A team of researchers recently postulated a genetic classifier with the ability to predict the sensitivity of neoadjuvant chemotherapy for breast cancer in the area of tumor molecular markers.

16 Sep 2021

Researchers infer chemical steps involved in methylthiolation of tRNAs

Recent research revealed the chemical steps in a vital cellular modification mechanism that inserts a chemical tag to certain RNAs. Interference of this process in humans can result in cancers, diabetes, and neuronal diseases.

From Penn State University 16 Sep 2021

Genomics data helps explain the world's biggest migration of sardines

Scientists have discovered how the Sardine Run, one of the world's biggest migration events, works.

16 Sep 2021

Scientists use stem cells to investigate the genetic risk for Alzheimer's disease

AD, the most frequent cause of dementia, affects an estimated 24 million people worldwide. With very limited treatment options, scientists are looking for ways to understand the disease better.

16 Sep 2021

UTHSC researcher receives grant to extend work on The Cancer Genome Atlas project

Neil Hayes, MD, MPH, director of the Center for Cancer Research at the University of Tennessee Health Science Center, is one of two principal investigators for a $1.8 million grant that extends the work of The Cancer Genome Atlas (TCGA), a groundbreaking multisite project to understand cancer at its molecular level through genome sequencing and extensive data analysis.

16 Sep 2021

Programmable DNA-based microfluidic chip for performing complex mathematical calculations

The term 'DNA' immediately calls to mind the double-stranded helix that contains all our genetic information. But the individual units of its two strands are pairs of molecules bonded with each other in a selective, complementary fashion.

15 Sep 2021

Scientists develop a technique for reconstructing whole genomes on a personal computer

Scientists at the Massachusetts Institute of Technology and the Institut Pasteur in France have developed a technique for reconstructing whole genomes, including the human genome, on a personal computer.

From Massachusetts Institute of Technology (MIT) 15 Sep 2021

New drug-based genetic platform offers a simpler, more efficient way to study gene function

Studying the role genes play on basic biology and disease is now easier, faster and more efficient, say researchers at Baylor College of Medicine.

15 Sep 2021

Jumpcode Genomics collaborates with TGen to investigate the genomic epidemiology of SARS-CoV-2

Jumpcode Genomics, a genome technology platform company focused on improving the understanding of human biology, announced today a collaboration with the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, to aid investigations into the genomic epidemiology of SARS-CoV-2, the virus that causes COVID-19.

14 Sep 2021

Newly discovered RNA-guided endonucleases can be harnessed for genome editing in cells

Researchers seeking to understand the origins of CRISPR-Cas9 systems have uncovered a class of transposon-encoded RNA-guided nucleases, which they dubbed "OMEGA," that could be harnessed for genome editing in human cells.

14 Sep 2021

Study unravels the DNA repair mechanism by enzymes

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

Study uncovers mechanism where two transcription factors stabilize each other’s binding to DNA

Researchers have discovered an exclusive mechanism through which two transcription factors stabilize each other’s binding to DNA in fission yeast.

14 Sep 2021

New approach to identify molecular targets for improved prostate cancer therapy

In a new study, researchers have introduced DSER, a technique for identifying molecular targets for enhanced therapy in prostate cancer.

14 Sep 2021

Genomics

Researchers provide novel treatment target for common skin condition

Genetic and epigenetic origin of pediatric liver cancer uncovered

Researchers seek to point a way toward a unified theory for DNA folding

Study finds greater facial asymmetry in parents of autistic individuals

Research provides novel insight into plant chloroplasts and proteins within

Researchers describe investigations into an enigmatic group of coral-infecting microbes

Hundreds of mutated tumor suppressor genes can help cancer cells evade the immune system

New genetic classifier can predict the sensitivity of chemotherapy for breast cancer

Researchers infer chemical steps involved in methylthiolation of tRNAs

Genomics data helps explain the world's biggest migration of sardines

Scientists use stem cells to investigate the genetic risk for Alzheimer's disease

UTHSC researcher receives grant to extend work on The Cancer Genome Atlas project

Programmable DNA-based microfluidic chip for performing complex mathematical calculations

Scientists develop a technique for reconstructing whole genomes on a personal computer

New drug-based genetic platform offers a simpler, more efficient way to study gene function

Jumpcode Genomics collaborates with TGen to investigate the genomic epidemiology of SARS-CoV-2

Newly discovered RNA-guided endonucleases can be harnessed for genome editing in cells

Study unravels the DNA repair mechanism by enzymes

Study uncovers mechanism where two transcription factors stabilize each other’s binding to DNA

New approach to identify molecular targets for improved prostate cancer therapy

Driving Support for Pharmaceutical Testing Through Continuous Innovation

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