Genomics

RSS

Rice biologists embark on a three-year project to create genetically encoded antibiotics

Synthetic biologists at Rice University are embarking on a three-year project to create "genetically encoded antibiotics," strands of RNA that bacteria will readily copy and share that will selectively kill only disease-causing, pathogenic bacteria.

14 Mar 2023

Understanding the factors that impact CRISPRa efficiency

Investigators, from the Wellcome Sanger Institute and partners, utilized human stem cells and neurons to explore what attributes impact how well CRISPR activation works for different sets of genes.

14 Mar 2023

TurboID-based proximity labeling in meiotic cells of Arabidopsis thaliana

During meiosis, reshuffling of genetic information between homologous chromosomes through meiotic recombination creates variable gametes and hence genetic variation in offsprings.

14 Mar 2023

Study investigates schizophrenia risk across African ancestry

Researchers have identified two previously unknown genes linked to schizophrenia and newly implicated a third gene as carrying risk for both schizophrenia and autism. Led by the Icahn School of Medicine at Mount Sinai, the multi-center study further demonstrated that the schizophrenia risk conferred by these rare damaging variants is conserved across ethnicities. The study may also point to new therapeutics.

14 Mar 2023

Study investigates the complex evolutionary history of jewel beetles' vision

Jewel beetles are striking insects, easily recognized by their vivid colors and metallic sheen. Possessing large, well-developed eyes, jewel beetles use vision and color for a range of different behaviors, including finding mates and host plants.

13 Mar 2023

A reliable way to downregulate gene translation in plants

By carefully constructing upstream open reading frames (uORFs), Caixia Gao’s team at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences (CAS) has created a new technique for downregulating gene translation to a predictable and desirable level in plants.

10 Mar 2023

Bean genome sequencing to boost nutritional quality

The faba bean genome, which has been sequenced for the first time and published in Nature on March 8th, 2023, is more than four times as large as the human genome at 13 billion bases.

From University of Reading 10 Mar 2023

Novel model tracks hippocampal synaptic plasticity to reveal molecular mechanisms

The accumulation of amyloid beta proteins, which encourage synaptic malfunction, causes cognitive decline in Alzheimer’s disease (AD), according to scientific evidence.

10 Mar 2023

Gaining deep insights into mezcal worms

Mezcal is a distilled alcohol made from the boiled and fermented sap of agave plants. Most mezcal beverages -; including all brands of tequila -; are sold as pure distillates, but a few have an added stowaway bottled inside: worms.

10 Mar 2023

Study identifies a novel rare mutation in gene linked to Harlequin Ichthyosis

Harlequin ichthyosis (HI) is a severe genetic skin disorder characterized by thick white, brown, or dark brown patches on the skin covering a newborn's entire body. HI has a low incidence of 1 per 300,000 live births but comes with the highest mortality rate among skin conditions. It is caused by a mutation in the ABCA12 gene, which codes for a protein involved in transporting lipids necessary for the formation of the skin barrier. Such protein shortage leads to a weaker epidermal barrier.

9 Mar 2023

“Bacterial suicide squad” recruits and activates innate and adaptive antitumor immune responses

Combining discoveries in cancer immunology with sophisticated genetic engineering, Columbia University researchers have created a sort of "bacterial suicide squad" that targets tumors, attracting the host's own immune cells to the cancer to destroy it. The new work, published today in Science Advances, marks a major step forward in efforts to enlist non-pathogenic bacteria to combat cancer.

9 Mar 2023

New gene resource for improving root systems

A strong root system allows crops to absorb water and nutrients from the soil, but scientists have little information about the genes that control root development. Recent research published in New Phytologist reveals that blocking a negative regulator gene of root development leads to enhanced root growth in plants.

8 Mar 2023

Experts sequence the faba bean genome

The faba bean genome, which at 13 billion bases is more than four times the size of the human genome, has been sequenced for the first time and is published today (08 March 2023), in Nature. This is an extraordinary technical achievement and crucial to efforts to breed beans with optimum nutritional content and sustainability of production.

8 Mar 2023

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Scientists discover mechanism behind how plants can develop long-term immunity to stress

A mechanism behind how plants can develop long-term immunity to stress has been discovered by scientists at the University of Sheffield.

8 Mar 2023

Discovery could establish an effective control environment for chromosome instability

A research team, affiliated with UNIST has unveiled a key factor involved in the DNA damage response (DDR), homologous recombination (HR) and DNA interstrand crosslink (ICL) repair.

8 Mar 2023

Socioeconomic and genetic factors likely interact in an additive way to increase risk of metabolic diseases

New research led by investigators at Massachusetts General Hospital, a founding member of Mass General Brigham, indicates that socioeconomic and genetic factors likely interact in an additive way to affect people's risks of developing obesity and type 2 diabetes.

8 Mar 2023

BGI’s fluorescent RT-PCR kit obtains market access qualification for detecting SARS-CoV-2, IFV A, IFV B in Australia

On March 2, BGI's Multiplex Real-time Fluorescent RT-PCR Kit for Detecting SARS-CoV-2, Influenza A Virus and Influenza B Virus obtained market access qualification to enter the Australian Register of Therapeutic Goods.

8 Mar 2023

An alternative option to treat ADCY5-related dyskinesia in patients

The asthma medication theophylline can be used to treat the movement disorder ADCY5-related dyskinesia. A recent study conducted by Martin Luther University Halle-Wittenberg (MLU), University Medicine Halle, and the University of Leipzig Medical Center demonstrated this.

7 Mar 2023

Using data from Sanger sequencing to quantify of genetic variants in bacterial cultures

Genetic variations, such as mutations, recombinations, or transpositions occur naturally in cultured microorganisms and are often considered nonneutral mutations.

7 Mar 2023

Genomics

Rice biologists embark on a three-year project to create genetically encoded antibiotics

Understanding the factors that impact CRISPRa efficiency

TurboID-based proximity labeling in meiotic cells of Arabidopsis thaliana

Study investigates schizophrenia risk across African ancestry

Study investigates the complex evolutionary history of jewel beetles' vision

A reliable way to downregulate gene translation in plants

Bean genome sequencing to boost nutritional quality

Novel model tracks hippocampal synaptic plasticity to reveal molecular mechanisms

Gaining deep insights into mezcal worms

Study identifies a novel rare mutation in gene linked to Harlequin Ichthyosis

“Bacterial suicide squad” recruits and activates innate and adaptive antitumor immune responses

New gene resource for improving root systems

Experts sequence the faba bean genome

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Scientists discover mechanism behind how plants can develop long-term immunity to stress

Discovery could establish an effective control environment for chromosome instability

Socioeconomic and genetic factors likely interact in an additive way to increase risk of metabolic diseases

BGI’s fluorescent RT-PCR kit obtains market access qualification for detecting SARS-CoV-2, IFV A, IFV B in Australia

An alternative option to treat ADCY5-related dyskinesia in patients

Using data from Sanger sequencing to quantify of genetic variants in bacterial cultures

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics