Molecular & Structural Biology

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Gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia

A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson of the National Institute on Aging and colleagues.

17 Dec 2021

Researchers create a healthier form of starch in the cassava plant

Researchers at the RIKEN Center for Sustainable Resource Science (CSRS) in Japan have recently created a healthier form of starch in the cassava plant. Published in the scientific journal Plant Molecular Biology, the study shows how reducing levels of starch branching enzymes (SBEs) in cassava plants changes the composition of tapioca starch, making it more resistant to digestion and healthier for us to eat.

17 Dec 2021

Study unravels novel gene vital for establishing proper left-right asymmetry

A group of scientists headed by the Agency for Science, Technology and Research’s (A*STAR) recently identified a new gene.

17 Dec 2021

Experts investigate link between COVID-19 and Parkinson’s disease

Case reports of younger COVID-19 patients developing Parkinson’s disease within weeks of contracting the virus led researchers to investigate a possible link between the two conditions.

17 Dec 2021

Protein protects against heart damage following cancer treatment

Cancer treatment is hard on the body, however for the patient to endure cancer, it is mostly necessary to undergo the treatment.

17 Dec 2021

Lack of genetic switch results in malformations during embryonic development

A group of researchers identified how a minor disturbance in the activation mechanism of this gene triggers the origin of clubfoot, a common foot malformation.

17 Dec 2021

Genetic mutation appears to be a predisposing factor for COPD independent of smoking

In 2019, the WHO positioned chronic obstructive pulmonary disease (COPD) third in the global ranking of causes of death.

From Institut Pasteur 15 Dec 2021

Experts identify ways to manipulate capsule-like DNA structures

Biophysicists from Japan recently identified ways to create and manipulate capsule-like DNA structures that can be employed in the development of artificial molecular systems.

14 Dec 2021

Study reveals the biochemistry of long-term memory consolidation

Scientists from Tokyo Metropolitan University recently gained a deeper understanding of the biochemistry of long-term memory.

14 Dec 2021

Study finding helps better comprehend necroptosis for treating diseases

A group of scientists from WEHI, for the first time, visualized a human cell death complex associated with autoimmune and inflammatory conditions.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 14 Dec 2021

New mechanism makes cells under stress conditions stop their polarized growth

The Oxidative Stress and Cell Cycle Research Group at UPF has discovered a mechanism whereby cells under stress conditions stop their polarized growth. The study, published in the journal Cell Reports, was led by Elena Hidalgo and José Ayté, and the first author is Clàudia Salat-Canela.

13 Dec 2021

Researchers regenerate cartilage using novel protein fragment

The existing methods for the regeneration of injured cartilage generate tissue that breaks down. This deterioration eventually leads to osteoarthritis—the commonly seen form of arthritis—affecting over 32.5 million grown-ups in the United States, as per the Centers for Disease Control and Prevention.

13 Dec 2021

First molecular structure of TDP-43 could pave the way for new ALS therapies

Scientists have determined for the first time the structure of the molecule associated with amyotrophic lateral sclerosis (ALS) and multiple other neurodegenerative diseases.

9 Dec 2021

Experts identify subgenome asymmetry at translational level in wheat

Polyploidy is a key route for the creation of new species in plants and a significant means of enhancing agronomic traits in crops.

9 Dec 2021

Immune cells utilize the body’s fat stores to combat infection, says study

A recent study carried out by the University of East Anglia and Quadram Institute shows how immune cells utilize the body’s fat stores to combat infection.

9 Dec 2021

Researchers identify protein that promotes wound healing and repair

Recent research discovered a protein known as Agrin that is known to promote wound healing and repair when induced after the injury of skin tissue.

8 Dec 2021

Scientists unravel the structure of octopus-like Lassa viral polymerase

Endemic in Western African countries, Lassa virus is transmitted to humans through food or household items that are contaminated with the urine or faeces of Mastomys rats.

7 Dec 2021

Cancer drug effective against Alzheimer’s disease, says research

According to recent research carried out by researchers from the Weill Cornell Medicine, a gene mutation associated with Alzheimer’s disease changes a signaling pathway in specific immune cells of individuals with the disease.

7 Dec 2021

Experts identify first non-coding RNA that controls chromosome loop formation

Recent research carried out by scientists from Massachusetts General Hospital (MGH) reveals that a significant player in the healthy development of female embryos also performs a vital role in controlling the behavior of chromosome loops and gene expression in both sexes.

7 Dec 2021