Molecular & Structural Biology

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CSHL researchers spotlight the role of a previously little-known protein in leukemia

Acute myeloid leukemia (AML) is an aggressive cancer of white blood cells with few effective targeted therapies available to treat it.

12 Jan 2022

Scientists discover new Senp5S protein with crucial role in brain development

Understanding how the brain develops is crucial to formulating treatments and management protocols for a variety of developmental disorders, as well as degenerative neurological diseases. Right from the embryonic stage, brain development is facilitated by the differentiation of neurons (brain cells).

12 Jan 2022

Study may pave the way for designing next generation of artificial chromosomes for data storage

Previously, researchers from Tianjin University designed and created a 254 kb digital data carrying artificial chromosome in yeast.

12 Jan 2022

Researchers reveal molecular and cellular mechanisms that lead to tertiary lymphoid structures formation

Tertiary lymphoid structures are formations that occur outside of the lymphatic system. They contain immune cells and are similar in structure and function to lymph nodes and other lymphoid structures.

12 Jan 2022

Experts determine the assembly of proteins with specialized protein needles

Protein assembly is considered to be an essential factor for the development of ordered biological structures, but how about engineering one.

10 Jan 2022

Sampling zoo air could help collect enough DNA to identify the animals nearby

The air in a zoo is full of smells, from the fish used for feed to the manure from the grazing herbivores, but now we know it is also full of DNA from the animals living there.

7 Jan 2022

A highly effective protection against oxidative stress developed by present-day humans

Very few proteins in the body have a change that makes them unique compared to the corresponding proteins in Neanderthals and apes. Researchers at the Max Planck Institute for Evolutionary Anthropology in Germany and Karolinska Institute in Sweden have now studied one such protein, glutathione reductase, which protects against oxidative stress.

From The Max Planck Institute 6 Jan 2022

Scientists discover how sponginess of stem cell nuclei controls cell differentiation

Researchers from Tokyo Metropolitan University have discovered how the sponginess and stickiness of stem cell nuclei controls how they "differentiate" into specialized cells. They found that the nucleus starts solid-like but becomes more fluid-like over time.

3 Jan 2022

Blocking function of blood-clotting protein prevents bone loss from gum disease in mice

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health.

24 Dec 2021

Unraveling how DNAzymes work in real time

DNAzymes are precision biocatalysts that destroy unwanted RNA molecules. However, major obstacles to their use in medicine remain.

23 Dec 2021

Study identifies two proteins as novel markers of aggressive prostate cancer

Prostate cancer is the most commonly diagnosed cancer in men and is among the top five causes of cancer-related death. In most cases, prostate cancer can be successfully treated but there is a group of patients who suffer an aggressive course and often fatal outcome.

23 Dec 2021

Discovery may lead to a better understanding of prion and other neurodegenerative diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP.

23 Dec 2021

European Union-funded project lifts digital data storage to a new level

One of the technologies that researchers are examining to offer effective and inexpensive alternatives for data storage in the future is DNA digital data storage.

23 Dec 2021

Study identifies novel function for existing protein

Researchers recently identified a new role of the protein tBID, which was to date linked to the regulatory role in cancer and cell death. But tBID also directly mediates apoptosis (controlled cell death).

23 Dec 2021

Experts identify proteins that regulate dual processes

According to recent research, the protein UBR7 acts as a histone chaperone and controls histone re-deposition at certain sites at the time of DNA replication.

22 Dec 2021

New method combines AI and microfluidics to easily barcode individual cells

An innovative new method for more efficient and accurate barcoding of individual cells could help realize faster diagnosis of diseases.

From University of Exeter 21 Dec 2021

Neural circuit coordinates breathing with negative emotions, says study

Recently, a group of Salk scientists unraveled a neural network in the brain that coordinates breathing rhythm with feelings of fear and pain.

21 Dec 2021

Antibiotic resistance genes hide in inactive bacteria, research reveals

Antibiotic resistance is a race between bacteria that are becoming resistant and humans who aspire to discover new antibiotics that helps in treating infectious diseases.

21 Dec 2021

Study provides novel insights into biological energy conversion

The respiratory chain performs a major role in the cell’s energy metabolism. It is localized in mitochondria—the power plants of the cell.

21 Dec 2021

Antibody-like proteins from sharks can neutralize SARS-CoV-2 variants

Small, unique antibody-like proteins known as VNARs -; derived from the immune systems of sharks -; can prevent the virus that causes COVID-19, its variants, and related coronaviruses from infecting human cells, according to a new study published Dec. 16.

17 Dec 2021

Molecular & Structural Biology

CSHL researchers spotlight the role of a previously little-known protein in leukemia

Scientists discover new Senp5S protein with crucial role in brain development

Study may pave the way for designing next generation of artificial chromosomes for data storage

Researchers reveal molecular and cellular mechanisms that lead to tertiary lymphoid structures formation

Experts determine the assembly of proteins with specialized protein needles

Sampling zoo air could help collect enough DNA to identify the animals nearby

A highly effective protection against oxidative stress developed by present-day humans

Scientists discover how sponginess of stem cell nuclei controls cell differentiation

Blocking function of blood-clotting protein prevents bone loss from gum disease in mice

Unraveling how DNAzymes work in real time

Study identifies two proteins as novel markers of aggressive prostate cancer

Discovery may lead to a better understanding of prion and other neurodegenerative diseases

European Union-funded project lifts digital data storage to a new level

Study identifies novel function for existing protein

Experts identify proteins that regulate dual processes

New method combines AI and microfluidics to easily barcode individual cells

Neural circuit coordinates breathing with negative emotions, says study

Antibiotic resistance genes hide in inactive bacteria, research reveals

Study provides novel insights into biological energy conversion

Antibody-like proteins from sharks can neutralize SARS-CoV-2 variants

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