Molecular & Structural Biology

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Cell survival protein could protect the kidneys from 'bystander' damage during cancer therapy

Australian researchers have identified a protein that could protect the kidneys from 'bystander' damage caused by cancer therapies.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 26 Nov 2020

Study shows how bacteria develop resistance to antibiotics

A group of researchers has successfully evolved the common microorganisms Escherichia coli at the experimental level.

25 Nov 2020

Study explains why immunotherapy works on certain patients with head and neck cancer

Researchers have found new clues about why certain individuals with head and neck cancer are able to respond to immunotherapy, while others fail to do so.

25 Nov 2020

Scientists identify key biological switch used in plant defense against animal attack

For decades, scientists have known that plants protect themselves from the devastation of hungry caterpillars and other plant-munching animals through sophisticated response systems, the product of millions of years of evolution.

From UC San Diego 25 Nov 2020

Novel targeted therapy blocks critical metabolic pathways in cancer cells

Scientists have designed a new targeted therapy, known as POMHEX, which inhibits vital metabolic pathways in tumor cells containing specific genetic defects.

24 Nov 2020

Study shows how drug-like small molecules regulate the activity of ion channels

Researchers have recently discovered how the function of therapeutically relevant ion channels is regulated by drug-like small molecules.

24 Nov 2020

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active "super immune cells" with strong antitumor activity, according to new research from Georgetown Lombardi Comprehensive Cancer Center.

24 Nov 2020

Study reveals genomic structures that allow SARS-CoV-2 virus to control the infection process

An international research alliance has visualized the RNA folding structures of the SARS-CoV-2 genome, for the first time.

23 Nov 2020

Plant used in traditional Chinese medicine becomes less visible to humans

According to a new study, a plant utilized in traditional Chinese medicine has emerged to become less perceptible to human beings.

From University of Exeter 23 Nov 2020

Researchers use metal-organic frameworks to target prostate cancer cells

Scientists have used metal-organic frameworks to effectively deliver the CRISPR/Cas9 genetic snipping tool into human cancer cells.

23 Nov 2020

Architecture of cell nucleus can change gene activity in plants

Scientists from the University of Tokyo have learned how the layout of the cell nucleus can alter the activity of genes found in plants.

23 Nov 2020

First functional analysis of cytokine IL-15L using rainbow trout

The cytokine family including interleukin-2 and -15 (IL-2 and IL-15) started out in a primitive vertebrate species with three related cytokines IL-2, IL-15, and IL-15-like (IL-15L), all sharing binding capacity for receptor chain IL-15Rα. IL-15L was conserved in fishes, reptiles, and some mammals but lost in humans and mice.

23 Nov 2020

Molecular & Structural Biology

Cell survival protein could protect the kidneys from 'bystander' damage during cancer therapy

Study shows how bacteria develop resistance to antibiotics

Study explains why immunotherapy works on certain patients with head and neck cancer

Scientists identify key biological switch used in plant defense against animal attack

Novel targeted therapy blocks critical metabolic pathways in cancer cells

Study shows how drug-like small molecules regulate the activity of ion channels

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Study reveals genomic structures that allow SARS-CoV-2 virus to control the infection process

Plant used in traditional Chinese medicine becomes less visible to humans

Researchers use metal-organic frameworks to target prostate cancer cells

Architecture of cell nucleus can change gene activity in plants

First functional analysis of cytokine IL-15L using rainbow trout

Biologists unravel how tissue geometry influences cell migration

New research opens up potential target for treating bone disorders

Scientists discover how abnormal proteins unleash latent toxicity in neurodegenerative diseases

Researchers investigate solutions to make cell membranes resistant to coronavirus entry

Scientists discover new functions of key cellular machine involved in human cancers

Study may lead to new strategies that minimize inflammatory reactions after cell transplants

Scientists elucidate the structure of ABC transporter protein

Study shows how brain protein helps pancreatic cancer cells to survive

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