3D bioprinting is a revolutionary method for creating carefully controlled 3D tissue constructions with tissue-like intricacy. 3D bioprinting is an additive manufacturing technology that uses 3D printing techniques to stack materials and create 3D tissue constructions.
Bioink, the substance used in 3D bioprinting, comprises living cells and biomaterials that imitate the extracellular matrix (ECM) environment, allowing cells to adhere, grow, and differentiate after printing. This developing innovation has the potential to address several major unmet needs in medical research, including cosmetics testing, drug development, in vitro models, and functional organ replacement.
Merck provides a broad range of biocompatible fit-for-purpose polymers, water-soluble photoinitiators, and additives designed exclusively for 3D bioprinting and tissue engineering applications. Many of these specialist materials have moieties that allow quick and easy crosslinking when exposed to UV or visible light, pH changes, thermal procedures such as sample warming, or even culture media.
Products for TissueFab® BIOINKS. Source: Merck
Product Number |
Product Name |
Product Description |
905429 |
TissueFab® bioink |
(Gel)ma -UV/365 nm |
906913 |
TissueFab® bioink |
Alg(Gel)ma -Vis/525 nm |
905410 |
TissueFab® bioink |
Alg(Gel)ma -UV/365 nm |
926019 |
TissueFab® bioink kit |
(Gel)ma Fibronection -Vis/405 nm, low endotoxin |
918741 |
TissueFab® bioink |
(Gel)ma -VIS/405nm, low endotoxin |
906905 |
TissueFab® bioink |
Sacrificial |
915033 |
TissueFab® bioink Bone |
Vis/405 nm |
921610 |
TissueFab® bioink |
(GelAlg)ma -Vis/405 nm |
927074 |
TissueFab® bioink kit |
(Gel)ma Fibrin (Vis/405), low endotoxin |
915963 |
TissueFab® bioink Conductive |
Vis/405 nm |
919926 |
TissueFab® bioink |
Crosslinking solution, low endotoxin |
926159 |
TissueFab® bioink Alg(Gel)ma -UV/365 nm |
- |
922862 |
TissueFab® bioink |
(GelAlgHA)ma -Vis/405 nm |
915637 |
TissueFab® bioink Bone |
support gel |
915726 |
TissueFab® bioink Conductive |
UV/365 nm |
927201 |
TissueFab® bioink |
(GelHA)ma -Vis/405nm, low endotoxin |
920983 |
TissueFab® bioink |
(GelAlg)ma -UV/365 nm |
915025 |
TissueFab® bioink Bone |
UV/365 nm |
919632 |
TissueFab® bioink |
(GelHA)ma -UV/365 nm |
919624 |
TissueFab® bioink |
(GelHA)ma -Vis/405 nm |
934437 |
TissueFab® bioink |
(GelHep)MA Vis/ 405nm, low endotoxin |
920975 |
TissueFab® bioink |
(GelAlgHA)ma -UV/365 nm |
926000 |
TissueFab® bioink kit |
(Gel)ma Laminin -Vis/405 nm, low endotoxin |
934178 |
TissueFab® bioink |
(GelHAHep)MA Vis/405 nm, low endotoxin |
926086 |
TissueFab® bioink Bone Vis/405 nm |
- |
926035 |
TissueFab® bioink Bone UV/365 nm |
- |
926078 |
TissueFab® bioink Conductive |
Vis/405 nm, low endotoxin |
926051 |
TissueFab® bioink Conductive |
UV/365 nm, low endotoxin |
Other Products. Source: Merck
Product Number |
Product Name |
Product Description |
925217 |
TissueFab® - low endotoxin GelMA-UV bioink |
0.2 μm filtered, suitable for 3D bioprinting applications |
930024 |
Hyaluronic acid adipic dihydrazide (HA-ADH) |
- |
933872 |
Carboxymethyl cellulose glycidyl methacrylate |
Degree of methacrylation ~10 % |
938424 |
TissueFab® Discrete GelMA |
90-110 bloom, 50 % degree of substitution |
934070 |
Ovine collagen |
3 mg/ml solution, low endotoxin |
925055 |
TissueFab® GelAlg − LAP Bioink |
low endotoxin, 0.2 μm filtered, suitable for 3D bioprinting applications |
938890 |
TissueFab® Discrete GelMA |
gel strength 300bloom, 20 % degree of substitution |
934089 |
Ovine collagen |
lyophilized, low endotoxin |
934135 |
TissueFab® Sodium Persulfate Solution |
low endotoxin |
934100 |
Ovine collagen |
maleimide functionalized, low endotoxin |
928623 |
Chamfered tips |
33G, 0.25", 25/box, black |
934097 |
Ovine collagen |
methacrylate functionalized, low endotoxin |
934119 |
Ovine collagen |
SPDP functionalized, low endotoxin |
935794 |
Multiphoton lithography bioink kit |
gelatin-based hydrogel bioink |
Product Features
- The large variety of functionalized synthetic polymers with reactive end groups makes it easier to create functional hydrogels, even for persons with minimal chemistry knowledge.
- Natural polymers, such as hyaluronic acid, chitosan, gelatin, alginate, and their derivatives, contain cross-linkable functional groups that mimic the mechanical and biochemical properties of the native extracellular matrix, as well as the surface chemistry required for cell attachment, proliferation, and differentiation.
- Thermally processable biodegradable polymers can create rigid structures, including polycaprolactones, polylactides, and PLGAs. These materials are strong and rigid, and they offer structural support for bone-like tissue structures
- Merck is constantly expanding the ready-to-use bioinks for extrusion-type 3D bioprinting. The bioinks are composed of a range of biomaterials, including natural polymers, decellularized extracellular matrix, synthetic polymers, and synthetic peptides
TissueFab® BIOINKS
With a comprehensive range of ready-to-use bioink formulations and detailed protocols, our TissueFab® bioinks are designed to achieve high printing fidelity, cell viability, and batch-to-batch reproducibility.