Heparin methacrylate (HepMa) is a functionalized natural polymer used in 3D bioprinting and tissue engineering.
Heparin, a naturally occurring linear biopolymer and highly sulfated glycosaminoglycan (GAG), has been shown to modulate binding to extracellular matrix proteins and sequester growth factors and cytokines, making it valuable in 3D applications. The methacrylate functionalization of heparin enables thermal or photochemical crosslinking through covalent conjugation. Heparin's high anionic charge density promotes significant swelling in water.
Applications
Heparin-based hydrogels are commonly utilized in tissue engineering, 3D bioprinting, and drug delivery applications.
Features and Benefits
- Extended shelf-life and stability.
- Batch control ensures reproducible models for preclinical toxicology testing and drug screening.