Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

SARS-CoV-2 protein effectively shuts down host protein production, shows study

A detailed study of a SARS-Cov-2 protein, Nsp1, with a central role in weakening the host anti-viral immune response shows that it effectively shuts down production ofproteins in the host.

20 Jul 2020

Research may help design new, highly selective generation of Alzheimer's drugs

With over 1.2 million people affected in Germany alone and over 50 million people worldwide, Alzheimer's disease, also referred to simply as Alzheimer's, is one of the greatest medical and social challenges of our time.

20 Jul 2020

Using blood samples to detect positive COVID-19 cases in 20 minutes

World-first research by Monash University in Australia has been able to detect positive COVID-19 cases using blood samples in about 20 minutes, and identify whether someone has contracted the virus.

20 Jul 2020

Yale researchers uncover mechanism driving Wolfram Syndrome

Yale pharmacology professor Barbara Ehrlich and her team have uncovered a mechanism driving a rare, lethal disease called Wolfram Syndrome and also a potential treatment.

20 Jul 2020

Study shows how proteins prevent DNA replication errors

Two rereading proteins on the DNA assembly line collectively work as an emergency stop button to inhibit replication errors.

20 Jul 2020

Study shows flotillin proteins have direct influence on cell membrane structure

Similar to all cells, bacteria have a membrane that protects them from the outside just like skin.

20 Jul 2020

Study: High levels of iron in the blood can prevent age-related damage

Genes linked to ageing that could help explain why some people age at different rates to others has been identified by scientists.

17 Jul 2020

Study shows how cells respond to nutrient deprivation

The idea of the cell as a city is a common introduction to biology, conjuring depictions of the cell's organelles as power plants, factories, roads, libraries, warehouses and more.

From Harvard Medical School 17 Jul 2020

Scientists gain insights into how parasitic bacterium gives rise to lesions

Bacteria of the genus Bartonella are parasites that can be transmitted to humans via insect bites and animal scratches, resulting in an infection known as "bartonellosis." Cat-scratch disease and trench fever are forms of bartonellosis caused by different Bartonella species infecting humans.

17 Jul 2020

Modified mRNAs improve efficiency of protein synthesis

Since mRNAs play a key role in protein synthesis in vivo, the use of mRNAs as medicines and for in vitro protein synthesis has been desired.

17 Jul 2020

New method reveals the dynamics of HIV Gag-protein lattice structure

Viruses are scary. They invade our cells like invisible armies, and each type brings its own strategy of attack. While viruses devastate communities of humans and animals, scientists scramble to fight back.

17 Jul 2020

Disseminated cancer cells hijack crucial iron micronutrients to survive

In order to survive within the remote and harsh anatomical microenvironments of the central nervous system, the disseminated cancer cells that cause rare yet deadly leptomeningeal metastases (LM) hijack crucial iron micronutrients from native macrophages, researchers report.

17 Jul 2020

A new approach to combat drug resistance in aggressive age-related macular degeneration

An international team of researchers led by Baylor College of Medicine and Houston Methodist has discovered a strategy that can potentially address a major challenge to the current treatment for choroidal neovascularization (CNV), an aggressive form of age-related macular degeneration, the leading cause of irreversible blindness in the elderly.

17 Jul 2020

Rare inherited mutation in TP53 gene predisposes to a wide range of cancers

Rare inherited mutations in the body's master regulator of the DNA repair system – the TP53 gene – can leave people at a higher risk of developing multiple types of cancer over the course of their lives.

17 Jul 2020

New technique increases the precision of gene editing

A group of biomolecular engineers from Rice University has now identified a C-worthy method that significantly improves the precision of gene editing.

17 Jul 2020

Substances that target oxytocin receptors can help treat various diseases

Oxytocin is the so-called “cuddle hormone” or “love hormone” that plays a role in strengthening the relationship between the mother and child and controlling social bonding.

17 Jul 2020

Researchers identify key enzyme that drives the production of ribosomes

Scientists have demonstrated that an enzyme fuels the production of ribosomes—the molecular machines that synthesize all cellular proteins.

From University of Toronto 17 Jul 2020

Study shows how breast cancer cells escape the immune system

Scientists have explained a new method that clearly shows how a crucial player in the body’s immune system is destroyed by breast cancer cells.

17 Jul 2020

Development of mammalian placenta depends upon simple twist of DNA

The development of the mammalian placenta depends upon an unusual twist that separates DNA's classic double helix into a single-stranded form, Yale researchers report July 15 in the journal Nature.

16 Jul 2020

New, promising CAR T cell therapy results in exceptional patient recovery

In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of cancerthe cells.

16 Jul 2020