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Scalable Approach to Uncover Biological Discoveries from Single-Cell Data

To comprehend how even the smallest details affect human biology, researchers have compiled enormous single-cell gene expression databases.

9 Jan 2025

Rewriting History: Advanced Genetic Analysis Uncovers Ancient Ancestry Shifts in Europe

High-resolution analysis of ancient genomes reveals key Scandinavian ancestry movements in early medieval Europe, highlighting complex genetic interactions.

9 Jan 2025

Mapping the Aging Brain: A Single-Cell View of Transcriptomic Changes

Research reveals how aging impacts gene expression across brain cell types, identifying critical changes in the hypothalamus linked to health and function.

9 Jan 2025

Researchers Uncover Genetic and Environmental Interplay in Bacterial Growth

Genetic and environmental factors influence cell growth. Although previous studies have evaluated the influence of these factors on growth, conducting studies that assess such factors in a cross-talk manner is necessary.

8 Jan 2025

New Genomic Evidence Sheds Light on Early Migration into Wallacea

A new study from the University of Adelaide and The Australian National University (ANU) has outlined the first genomic evidence of early migration from New Guinea into the Wallacea, an archipelago containing Timor-Leste and hundreds of inhabited eastern Indonesian islands.

8 Jan 2025

Weak Molecular Interactions Trigger Autophagy in Cells

Recycling takes place in our cells at all times: in a process called autophagy, cell components that are no longer needed are enclosed by membranes and broken down into their basic building blocks.

8 Jan 2025

New Insights into Nuclear Lipid Droplets as Regulators of Aging and Metabolic Health

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 22 on December 9, 2024, entitled "Nuclear lipid droplets: a novel regulator of nuclear homeostasis and aging."

8 Jan 2025

Uncovering the Ancient Genetic Secrets of Hornworts

Over 450 million years ago, plants began the epic transition from water to dry land. Among the first pioneers were the ancestors of humble hornworts, a group of small, unassuming plants that have persisted to this day.

7 Jan 2025

Researchers Discover Genetic Markers for PFAS-Induced Neurotoxicity

Per- and polyfluorinated alkyl substances (PFAS) earn their "forever chemical" moniker by persisting in water, soil and even the human brain.

7 Jan 2025

New Mechanism Revealed for Immune Response to DNA Damage

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged.

7 Jan 2025

Unique CO₂-Concentrating Mechanism Drives the Future of Sustainable Agriculture

Researchers have been exploring methods to enhance the ability of plants to convert carbon dioxide (CO₂) into biomass, a process that could increase crop yields and contribute to climate change mitigation.

7 Jan 2025

CryoSCAPE Enables Accurate Single-Cell Profiling in Diverse Populations

Human blood is a complex and delicate mixture, often used by researchers and clinicians to understand the body’s inner workings.

7 Jan 2025

Zinc Stress Exposes Vulnerabilities in Drug-Resistant Bacteria

McMaster University researchers have identified zinc or the lack of it as a crucial weakness in drug-resistant bacteria.

7 Jan 2025

Unexpected Role for CDKN2A Gene in Esophageal Cancer Progression

Scientists from the Barts Cancer Institute and the Francis Crick Institute have demonstrated that a genetic flaw that has long been thought to cause esophageal cancer may actually protect against the disease in its early stages.

6 Jan 2025

Next-gen ‘smart cells’ take a major step forward

A new building kit for creating unique sense-and-respond circuits in human cells has been created by bioengineers at Rice University.

6 Jan 2025

Uncovering Key Differences Between Humans and Mice in Cancer Immunotherapy Targets

“Programmed cell death protein 1,” or PD-1, has been considered a key target in cancer therapies since its discovery in the 1990s.

6 Jan 2025

Genetic Discovery Offers Potential for Higher Crop Yields and Biofuel Production

A team of scientists with two Department of Energy Bioenergy Research Centers -; the Center for Bioenergy Innovation, or CBI, at Oak Ridge National Laboratory and the Center for Advanced Bioenergy and Bioproducts Innovation, or CABBI, at the University of Illinois Urbana-Champaign -; identified a gene in a poplar tree that enhances photosynthesis and can boost tree height by about 30% in the field and by as much as 200% in the greenhouse.

6 Jan 2025