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CAR-T cell treatment via implantable biotechnology more effective in combating cancer

Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed an implantable biotechnology that produces and releases CAR-T cells for attacking cancerous tumors.

25 Mar 2022

New BGI research lays groundwork for organ regeneration

Scientists declared the invention of a transgene-free and manageable method to transform pluripotent stem cells into bona fide 8-cell totipotent embryo-like cells.

23 Mar 2022

New database provides extensive information on kinase-associated neural protein phosphorylation

Biological functions rely on accurate cellular communication involving different molecules. Most major signaling pathways involved in such communication, called signal transduction, often involve a family of kinases—enzymes catalyzing the transfer of phosphates between specific substrate molecules.

17 Mar 2022

Multi-omics approach help researchers study the disparity created by in vitro culture

Citrus is a significant and economically beneficial horticultural crop with nucellar polyembryony, which prevents hybrid offspring from being produced. Citrus is produced mostly through asexual methods like grafting and cuttings.

7 Mar 2022

Study shows how the release of T-cell cytokine combined with fatty acid leads to ferroptosis

Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.

7 Mar 2022

Researchers optimize a route for two-step synthesis of antiviral plant protectant

Plant viruses are of great variety and harm. Virus disease pandemics and epidemics were estimated to have a global economic impact in the tens of billions of dollars.

3 Mar 2022

HDO technology found to be effective at silencing problematic genes

T and B lymphocytes, which are part of a group of immune cells commonly called white blood cells, work together to eliminate foreign invaders in the body such as viruses.

1 Mar 2022

Newly developed radio-labeled molecule may be able to pinpoint areas of inflammation

Researchers at The University of Texas MD Anderson Cancer Center have developed a new radio-labeled molecule capable of selectively reacting with certain high-energy radicals that are characteristic of innate immune activity, which may allow a non-invasive approach to monitor inflammation in real time by positron emission tomography (PET) imaging.

22 Feb 2022

Discovery of chiral evasion could lead to more resilient inhibitors, better drug designs

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial infection that has become resistant to most of the antibiotics used to treat regular staph infections.

18 Feb 2022

New study deepens the understanding of microbial sulfur metabolism

The metabolism of sulfur compounds is among the most important microbial processes sustaining life in many anoxic environments where oxygen is not present.

18 Feb 2022

Moving cell groups push forward as they form organs, become cancerous and spread

Cells push and pull on surrounding tissue to move in groups as they form organs in an embryo, track down invading bacteria, and become cancerous and spread.

From New York University (NYU) 15 Feb 2022

Experts identify the master regulator of Nodal signaling in human embryonic stem cells

A new study has led to the discovery that the Hippo signaling effector YAP1 is a master controller of Nodal signaling in hESCs for a process crucial to human development.

14 Feb 2022

Pro-regenerative metabolite supports elevated tissue regeneration and delays aging, study reveals

Research recognizes uridine as a pro-regenerative metabolite that highlighted human stem cell activity and improved restructuring and tissue repair.

14 Feb 2022

P53 protein induces leader cell behavior, migration and clearance during epithelial tissue repair

New research led by the University of Bristol has found the protein p53 plays a key role in epithelial migration and tissue repair.

11 Feb 2022

Gene-editing techniques could be used to tackle mitochondrial disorders, study shows

Defective mitochondria – the 'batteries' that power the cells of our bodies – could in future be repaired using gene-editing techniques.

9 Feb 2022

Cryobioprinting; A New Bioprinting Technique

In this interview, we speak to Dr. Y. Shrike Zhang about his latest bioprinting technique that allows tissues to be preserved for later use.

From Harvard Medical School 4 Feb 2022

Leukemia-on-a-chip; The Future of Preventing Therapy Resistance?

We speak to Dr. Chao Ma, one of the speakers at SLAS 2022, about his groundbreaking 'leukemia-on-a-chip' technology and its future within therapy resistance.

From Society for Laboratory Automation and Screening (SLAS) 27 Jan 2022

Respiration entrains and coordinates neuronal activity in various brain regions

LMU neuroscientists have shown that breathing coordinates neuronal activity throughout the brain during sleep and quiet.

25 Jan 2022

Producing New Antibiotics Through Gene Editing

In this interview, we speak to Professor Jason Micklefield about his latest research that may be able to produce new antibiotics through gene-editing technologies.

From The University of Manchester 24 Jan 2022

Study findings greatly expand the ability to engineer long-range genome edits

Researchers discovered the potential of CRISPR, a tool used by bacteria to defend themselves against viral intruders, nearly a decade ago.

24 Jan 2022