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New technique reveals how environmental changes affect the dynamic structures of RNAs in living cells

The impact of environmental conditions on the dynamic structures of RNAs in living cells has been revealed by innovative technology developed by researchers at the John Innes Centre.

18 Aug 2022

Inventia Life Science and BioLamina partner to advance cell matrices for complex 3D cell models

As a result of this partnership, Inventia Life Science will now offer BioLamina’s extensive range of Biolaminin® products incorporated into the pre-validated library of RASTRUM™ Matrices, recapitulating the key motifs found in the native tissue of various cell types.

From Inventia Life Science 16 Aug 2022

Scientists demonstrate a new function of an enzyme that connects to age-related diseases

Aging and age-related diseases present a complex challenge to biomedical researchers.

20 Jul 2022

Research combines robotics and biology to create biohybrid microrobots using E. coli

A team of scientists from the Max Planck Institute for Intelligent Systems’ Physical Intelligence Department merged robotics and biology by outfitting E. coli bacteria with artificial components to create biohybrid microrobots.

From The Max Planck Institute 18 Jul 2022

How can High-Content Screening accelerate Drug Discovery?

As part of our SLAS Europe 2022 coverage, we speak to Professor Jeremy Simpson from the University College Dublin about the role high-content screening can play in accelerating drug discovery.

From Society for Laboratory Automation and Screening (SLAS) 6 Jul 2022

New technique shows how tRNA folding changes help to treat RNA-linked diseases

Researchers have developed a novel technique to analyze the composition and quantity of “transfer RNAs, which are tiny, chemically modified RNAs involved in protein synthesis.

From Penn State University 1 Jul 2022

Scientists discover proteins that may improve CAR-T cell therapy for solid tumor model

The potential of CAR T-cell therapy for the treatment of solid tumors was unlocked in a preclinical trial by researchers at St. Jude Children’s Research Hospital who discovered a molecular mechanism. The findings were released in the journal Nature.

27 Jun 2022

Study reveals possibility of changing the identity of synapses through enzymatic means

As you're reading this sentence, the cells in your brain, called neurons, are sending rapid-fire electrical signals between each other, transmitting information.

14 Jun 2022

OTUD3 shows opposing effects in innate immunity to RNA and DNA viruses

The identification of pathogen-associated molecular patterns (PAMPs) by pattern-recognition receptors (PRRs) is the first step in initiating an immune response to viral infection.

13 Jun 2022

ZDHHC18-mediated MDH2 palmitoylation upholds mitochondrial respiration and boosts ovarian cancer malignancy

To drive anabolic processes, epithelial ovarian cancer (EOC) is heavily reliant on the tricarboxylic acid (TCA) cycle and oxidative phosphorylation.

13 Jun 2022

Researchers discover a new interferon-gamma receptor signaling pathway

The interferon-gamma receptor (IFNgR) signaling pathway has been identified to be crucial for the vulnerability of glioblastoma tumors to death by CAR T-cell immunotherapy, according to researchers at Massachusetts General Hospital (MGH).

10 Jun 2022

Researchers analyze functional microglia to empower retinal organ

Professor Zi-Bing Jin is in charge of this research (Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, and Capital Medical University). He has spent the last decade working on retinal organoids, which can accurately mimic retinal development.

3 Jun 2022

in vivo News and Research

New technique reveals how environmental changes affect the dynamic structures of RNAs in living cells

Inventia Life Science and BioLamina partner to advance cell matrices for complex 3D cell models

Scientists demonstrate a new function of an enzyme that connects to age-related diseases

Research combines robotics and biology to create biohybrid microrobots using E. coli

How can High-Content Screening accelerate Drug Discovery?

New technique shows how tRNA folding changes help to treat RNA-linked diseases

Scientists discover proteins that may improve CAR-T cell therapy for solid tumor model

Study reveals possibility of changing the identity of synapses through enzymatic means

OTUD3 shows opposing effects in innate immunity to RNA and DNA viruses

ZDHHC18-mediated MDH2 palmitoylation upholds mitochondrial respiration and boosts ovarian cancer malignancy

Researchers discover a new interferon-gamma receptor signaling pathway

Researchers analyze functional microglia to empower retinal organ

Researchers analyze the chemical and biophysical properties of protein corona

Researchers create human cornea-on-a-chip to check the therapeutic effect of MSC exosomes on corneal disorders

Scientists demonstrate how stomach stem cells switch from one state to the other upon injury

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Researchers develop primitive endoderm stem cells in mice

New research identifies a destination for zinc chaperone protein's deliveries

New supramolecular CRISPR–Cas9 carrier supports much effective genome editing

Researchers highlight a phage-antibiotic combo against antibiotic-resistant superbug

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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