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Small fluorescent protein helps researchers to capture deeper, more precise biomedical images

Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have designed a small fluorescent protein that emits and absorbs light that penetrates deep into biological tissue.

7 Dec 2022

New 3D organoid model reveals a possible biological target for treating GEJ cancers

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

2 Dec 2022

Revealing the unappreciated role of POLQ in responding to DNA replication stress

Researchers at the Francis Crick Institute, in partnership with Artios, have discovered how an enzyme involved in DNA repair (POLQ) becomes critical to the survival of some tumors when the cancer cells lose the ability to employ a more frequent way of DNA repair.

1 Dec 2022

Using nanotechnology and magnetic manipulations to bioengineer 3D neural networks

Neurons are the fundamental units of the brain and nervous system, the cells responsible for receiving sensory input from the external world, for sending motor commands to our muscles, and for transforming and relaying the electrical signals at every step in between.

30 Nov 2022

Revealing the mechanism that ensures genome stability in normal cells

To create new cells, the old cells must divide. This is a constant, frequent, and pervasive process that begins with conception and culminates with death.

30 Nov 2022

Discovery provides insights into how invertebrates have evolved complex nervous systems

Octopuses are not much like humans -; they are invertebrates with eight arms, and more closely related to clams and snails.

29 Nov 2022

Scientists discover how plant roots adapt their shape to maximize water uptake

Researchers have discovered how plant roots adapt their shape to maximise their uptake of water, pausing branching when they lose contact with water and only resuming once they reconnect with moisture, ensuring they can survive even in the driest conditions.

19 Nov 2022

AXT Bring Novel Photoacoustic Imaging Technology to Australian Medical Researchers

AXT is pleased to announce a further expansion to their preclinical imaging portfolio with the addition of Luxonus

From AXT Pty Ltd 15 Nov 2022

Meet Dragonfly 600, Oxford Instruments’ new flagship confocal microscope

Oxford Instruments Andor, a world leader in scientific imaging solutions, has today announced the launch of Dragonfly 600, further strengthening its award-winning confocal microscopy portfolio.

From Andor Technology Ltd. 10 Nov 2022

Actin serves as catalyst for shaping the cells

In a recent study, scientists from the University of Maryland have explained how actin, a protein, plays a key role in giving cells their shape.

8 Nov 2022

Providing structural understanding of the influenza virus

The structure of the influenza replication machinery and how it interacts with cellular proteins have been solved by a team of Oxford University scientists using a variety of techniques at Diamond Light Source.

8 Nov 2022

Andor Launches New ZL41 Cell and Sona sCMOS Cameras

Andor Technology, an Oxford Instruments company and a world leader in scientific imaging solutions, has today announced the launch of two new scientific CMOS cameras, specifically designed for life science researchers.

From Andor Technology Ltd. 7 Nov 2022

Researchers uncover a mechanism of flowering plant sperm compaction

Sperm cells have compact bundles of DNA, yet exactly how and why sperm cell nuclei are condensed in flowering plants has been a mystery, until now.

4 Nov 2022

High-throughput quantitative phase microscopy yields promising results

Numerous cellular life processes include the organelles of cells. Their malfunction and the growth and spread of cancer are strongly connected.

4 Nov 2022

New bioprinting platform to replicate tumors in 3D spheroids

Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumors in 3D models.

3 Nov 2022

Identifying the structure of the SEA complex

The mTOR protein is important for cell growth, proliferation, and survival. Its activity fluctuates according to nutrient availability and growth factors like hormones.

1 Nov 2022

Conserved vacuolar sorting hub regulates autophagic flux in plants

A “hub and spoke” system allows plant cells to effectively coordinate cellular trafficking, especially for cellular recycling, also known as autophagy. Autophagosomes are specialized vesicles that capture hazardous molecules and transport them to the vacuole, where they are destroyed.

21 Oct 2022

Applying machine learning to define significant immune cells

The method correctly categorizes macrophage states, which is crucial since these cells can alter their behavior and function as either pro- or anti-inflammatory agents during an immune response.

20 Oct 2022

New approach to identify cancerous tissue for surgical removal

It is crucial to distinguish between tumors and healthy tissues during cancer surgery. Fluorescent markers can assist in this process by improving tumor contrast during surgery.

13 Oct 2022

Adults with congenital blindness experience striking recoveries of night vision after gene therapy

Adults with a genetic form of childhood-onset blindness experienced striking recoveries of night vision within days of receiving an experimental gene therapy, according to researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania.

11 Oct 2022