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Three proteins as potential new therapeutic targets in movement disorders

Three members of a family of proteins have been identified that are important to helping us fine tune the activity of brain chemicals which enable us to walk or stand at will, scientists report.

11 Feb 2022

Kras oncogenes use genetic reprogramming to drive tumorigenesis

Cancerous tumors are made up of rapidly growing, abnormally shaped, cells that can infiltrate and destroy healthy tissues, travel to other parts of the body, and form additional tumors.

8 Feb 2022

Different autism risk genes have similar effects on brain development, study finds

Autism spectrum disorder has been associated with hundreds of different genes, but how these distinct genetic mutations converge on a similar pathology in patients has remained a mystery.

3 Feb 2022

Researchers provide first evidence of the gene-environment interaction in the social dysfunctions typical of autistic disorders

Autism spectrum disorders are characterized by a wide range of behavioral issues.

2 Feb 2022

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

A University of South Florida Health (USF Health) preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

1 Feb 2022

Study identifies new therapy to treat cystic fibrosis

The process of making proteins from genes is similar to that of a factory, where employees must follow a set of instructions that are both effective and precise.

31 Jan 2022

Genetic mutation that corresponds to small body size in dogs existed in ancient wolves

Popular belief has been that small dogs, such as Pomeranians and Chihuahuas, exist because once dogs were domesticated, humans wanted small, cute companions.

28 Jan 2022

The Native Antigen Company Expands Range of Norovirus-Like Particles

The Native Antigen Company today announced the expansion of its norovirus-like particle range, with the addition of six new reagents.

From The Native Antigen Company 13 Jan 2022

New 'disease-in-a-dish' system developed to study oculocutaneous albinism

Researchers at the National Eye Institute have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA).

12 Jan 2022

Experts introduce new gene therapy approach for muscle weakness

Experts at Children’s National Hospital have created a new pre-clinical gene therapy for the rare condition limb-girdle muscular dystrophy (LGMD) 2B.

7 Jan 2022

Simple, marine-dwelling creature shines light on cancer resistance

A simple, marine-dwelling creature known as Trichoplax adhaerens has some remarkable properties. The organism can tolerate unusually high doses of radiation that would kill most other forms of life. T. adhaerens has another intriguing characteristic: the ability to resist cancer.

24 Dec 2021

Gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia

A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson of the National Institute on Aging and colleagues.

17 Dec 2021

Services to accelerate genome editing research

AMSBIO has expanded its range of custom gene editing services to complement its extensive portfolio of off-the-shelf CRISPR/Cas9 products.

From AMS Biotechnology 17 Dec 2021

Researchers use CRISPR-Cas9 to successfully target brown fat

Fat is an essential component of life, however too much fat leads to numerous health issues. Investigating the role played by fat or adipose tissue is significant to get a better understanding of obesity and other problems.

17 Dec 2021

Lack of genetic switch results in malformations during embryonic development

A group of researchers identified how a minor disturbance in the activation mechanism of this gene triggers the origin of clubfoot, a common foot malformation.

17 Dec 2021

What Role do Genes Play in the Development of Antibodies?

In this interview, we speak to researchers from the University of Toronto about their latest research that investigated the role genes play in the development of antibodies.

From University of Toronto 16 Dec 2021

Genetic mutation appears to be a predisposing factor for COPD independent of smoking

In 2019, the WHO positioned chronic obstructive pulmonary disease (COPD) third in the global ranking of causes of death.

From Institut Pasteur 15 Dec 2021

Study provides new insight into the genetics of severe schizophrenia

Columbia University researchers have determined that individuals who suffer from the most severe form of schizophrenia have a significantly higher number of rare mutations than more typical forms of the illness.

14 Dec 2021

Study reveals the biochemistry of long-term memory consolidation

Scientists from Tokyo Metropolitan University recently gained a deeper understanding of the biochemistry of long-term memory.

14 Dec 2021

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

Mutation News and Research

Three proteins as potential new therapeutic targets in movement disorders

Kras oncogenes use genetic reprogramming to drive tumorigenesis

Different autism risk genes have similar effects on brain development, study finds

Researchers provide first evidence of the gene-environment interaction in the social dysfunctions typical of autistic disorders

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

Study identifies new therapy to treat cystic fibrosis

Genetic mutation that corresponds to small body size in dogs existed in ancient wolves

The Native Antigen Company Expands Range of Norovirus-Like Particles

New 'disease-in-a-dish' system developed to study oculocutaneous albinism

Experts introduce new gene therapy approach for muscle weakness

Simple, marine-dwelling creature shines light on cancer resistance

Gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia

Services to accelerate genome editing research

Researchers use CRISPR-Cas9 to successfully target brown fat

Lack of genetic switch results in malformations during embryonic development

What Role do Genes Play in the Development of Antibodies?

Genetic mutation appears to be a predisposing factor for COPD independent of smoking

Study provides new insight into the genetics of severe schizophrenia

Study reveals the biochemistry of long-term memory consolidation

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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