Metabolomics News and Research

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Metabolomics is a field of research that focuses on the chemical processes undergone by metabolites. It involves the use of sophisticated analytical technologies to identify and quantify cellular metabolites, in addition to the extraction of relevant information so that the data can be interpreted and applied in a practical setting.

Promising Drug Offers Hope for Overcoming Resistance to Protein Degraders

Protein degraders, a novel approach in drug discovery, show promise to tackle diseases previously thought to be untreatable.

31 Jan 2024

“Free-from-Tree” Production of Vaccine Component QS-21

For the first time, a valuable chemical extracted from the soapbark tree and utilized as a major component in vaccinations has been duplicated in a different plant host, providing the vaccine industry with hitherto unheard-of potential.

29 Jan 2024

Breakthrough Research in Leishmaniasis Reveals Pain-Suppression Pathways

For the first time, scientists have begun to figure out why the disfiguring skin lesions caused by cutaneous leishmaniasis don't hurt.

1 Dec 2023

A Glimpse Into the World of Bacterial Metabolism Within Hosts

Researchers from Kiel University (CAU) and the Max Planck Institute for Marine Microbiology in Bremen are shedding light on the enigmatic world of bacteria that coexist or parasitize animal hosts.

9 Nov 2023

Scientists Discover New Pathway for Biosynthesis of Cardenolides in Plants

Scientists at the Max Planck Institute for Chemical Ecology in Jena are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants.

19 Sep 2023

Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

2 Jun 2023

High-Throughput Technique Observes Differences in Hard and Non-Hard Seeds

Alfalfa (Medicago sativa), also known as the “King of Grass,” is a legume cultivated in various parts of the world for animal feed. It is highly valued in the feed business because of its high protein content and biomass output.

8 May 2023

New Extraction Protocol Offers a More Comprehensive Picture of Cellular Activity

Researchers at the Van Andel Institute have created a new extraction protocol for RNA-seq and metabolomic analysis that provides a more comprehensive picture of cellular activity than either technique alone.

3 May 2023

New signals of natural selection in humans identified

A team of global experts has discovered new signals of natural selection in humans.

2 Mar 2023

Study shows why a specific gene mutation has opposite effects on mice and human cancers

A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new strategies for developing cancer treatments.

27 Feb 2023

New genetic research could make growing wheat in drought conditions easier in future

Growing wheat in drought conditions may be easier in the future, thanks to new genetic research out of the University of California, Davis.

24 Feb 2023

Metabolic reactions upon activating Akt2 enzyme revealed

Takeaki Ozawa and his team from the University of Tokyo reveal the metabolic reactions upon activating an enzyme called Akt2.

22 Feb 2023

Adding antioxidants to cell cultures for efficient production of antibodies

Researchers at the Department of Chemical Engineering, Indian Institute of Technology, India, have investigated the effects of oxidative stress on the production of monoclonal antibodies (mAbs), and how antioxidants can alleviate this stress to improve their performance.

16 Feb 2023

Researchers decipher how common environmental bacterium can digest complex waste

A common environmental bacterium, Comamonas testosteroni, could someday become nature's plastic recycling center.

7 Feb 2023

Revealing the functional significance of DDX41 in great detail

The DDX41 gene encodes the nuclear enzyme DEAD-box-type RNA helicase. Hematopoietic malignancies are caused by DDX41 mutations. However, the mechanism behind the development of this malignancy remains unknown.

21 Nov 2022

Drug discovery method facilitates promising treatment approaches for metabolic diseases

The body’s chemical processes known as “metabolism” produce the raw materials needed for development and general health.

17 Oct 2022

Developing a comprehensive framework to regulate GE crops

A Policy Forum article calls for a new method of regulating genetically engineered crops, claiming that the current procedures for mandating safety testing are inconsistent internationally.

8 Sep 2022

New method can identify the vast number of molecules derived from food

An international team of scientists, led by researchers at University of California San Diego, report a new method called untargeted metabolomics to identify the vast number of molecules derived from food that were previously unidentified, but that appear in our blood and our stool.

From UC San Diego 11 Jul 2022

New technique shows how tRNA folding changes help to treat RNA-linked diseases

Researchers have developed a novel technique to analyze the composition and quantity of “transfer RNAs, which are tiny, chemically modified RNAs involved in protein synthesis.

From Penn State University 1 Jul 2022

Enzymes found in capybara gut can promote the application of agroindustrial waste

One option to reduce dependence on oil and other fossil fuels is to transform agroindustrial waste into molecules of interest to society, like biofuels and biochemicals.

10 May 2022