Gene Expression News and Research

RSS

Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

New family of pharmaceutical compounds that target RNA

In Jennifer Hines’ lab, a group of graduate and undergraduate chemistry students recently discovered a new family of compounds that can target RNA and interfere with its function. In the future, RNA-targeted treatments to treat cancer and metabolic diseases, together with bacterial and viral infections, could be developed using the chemical scaffold found in this research.

15 Feb 2023

Versatile molecular toolbox expands the scope of gene regulation

Rice University scientists have enlisted widely used cancer therapy systems to control gene expression in mammalian cells, a feat of synthetic biology that could change how diseases are treated.

15 Feb 2023

Study charts seasonal and circadian genetic variation across the human body

The daily rotation of Earth and its yearly voyage around the Sun marks the natural rhythm of life on the planet.

14 Feb 2023

Study finds similar levels of DNA damage in vapers and smokers

E-cigarettes-; used regularly by more than 10% of U.S. teens and more than 3% of adults-; were once pitched as a healthy alternative to tobacco cigarettes.

14 Feb 2023

UChicago scientists shed light on the longstanding puzzle of RNA methylation

University of Chicago scientists have discovered a new wrinkle in our understanding of how our genes work.

14 Feb 2023

Research provides insight into the regulation of heartbeats

UT Southwestern Medical Center researchers have mapped gene control elements in specialized cardiac cells responsible for coordinating heartbeats. The findings of the genome exploration study, published in The Journal of Clinical Investigation, provide insight into how heartbeats are regulated and could impact diagnosis and risk prediction for a variety of common arrhythmias.

14 Feb 2023

Research reveals gene expression changes in two brain regions of individuals with cocaine use disorder

Individuals with cocaine use disorder exhibit gene expression changes in two brain regions: the nucleus accumbens, a region associated with reward, and the caudate nucleus, a region mediating habit formation, according to research conducted at the Icahn School of Medicine at Mount Sinai and published February 10 in Science Advances.

13 Feb 2023

Pancreatic islet microexons play key role in islet function and glucose homeostasis

When cells copy DNA to produce RNA transcripts, they include only some chunks of genetic material known as exons and throw out the rest.

10 Feb 2023

Genetic variants that increase the risk of ADHD identified

Why are some people diagnosed with ADHD while others are not? And when is the seed of ADHD sown, in life or the womb?

10 Feb 2023

Researchers pioneer a new approach to study mosquito's DNA

When it comes to DNA, one pesky mosquito turns out to be a rebel among species.

10 Feb 2023

UVA researchers discover a key trigger for common liver disease

University of Virginia School of Medicine researchers have discovered a key trigger for non-alcoholic fatty liver disease, a mysterious condition that causes fat to build up in the liver for no clear reason.

10 Feb 2023

Large-scale differentiation of iPSC-derived motor neurons from ALS patients

A new Cedars-Sinai study in collaboration with the University of California, Irvine (UCI) and the Answer ALS consortium has examined the expression of thousands of genes in stem cell generated motor neurons that are known to die in patients with amyotrophic lateral sclerosis, a fatal neurological disorder known as ALS or Lou Gehrig's disease.

10 Feb 2023

Researchers report the genome-wide atlas of chromatin-accessibility during stomatal development

Researchers at Nagoya University in Japan, the University of Texas at Austin, and the University of Washington have elucidated a mechanism that makes tiny plant stem cells destined to give rise to stomata, cellular valves of plants that facilitate global carbon cycles.

9 Feb 2023

Research lays the groundwork for using epigenome editing to improve crops

Cassava is one of the most important crops in the tropics, feeding half a billion people in more than 80 countries. Cassava bacterial blight (CBB) is a devastating disease that causes crop losses worldwide.

8 Feb 2023

A soybean genome in pan-3D

For cis-regulatory elements in the genome to function, which is crucial for gene regulation, a high-order chromatin structure is required. Three-dimensional (3D) genome organization in eukaryotes exhibits a hierarchical structure.

8 Feb 2023

Epigenetic editing to improve crops

One of the most significant crops in the tropics, cassava, provides food for 500 million people in more than 80 countries. The destructive disease known as cassava bacterial blight (CBB) results in crop losses all across the world.

8 Feb 2023

Gaining insights into human disease biology through CRISPR platforms

In this interview, we speak with Laralynne Przybyla about how she is utilizing CRISPR platforms to understand human disease biology in greater detail.

From Society for Laboratory Automation and Screening (SLAS) 7 Feb 2023

“Reference Epigenome” and regulatory mechanisms in wheat embryogenesis

One of the most basic and amazing processes that occur in both plants and animals is embryogenesis. It is incredible that, within a matter of weeks after fertilization, a single mother egg cell can transform into a living thing with a complex body structure.

6 Feb 2023

Study sheds light on why lung tumors do not respond well to immunotherapy

Immunotherapy -; drug treatment that stimulates the immune system to attack tumors -; works well against some types of cancer, but it has shown mixed success against lung cancer.

6 Feb 2023

Learning about cellular proteins through “snapshots” of translation

Pep-tRNAs, nascent polypeptides inside the ribosome that are covalently connected to transfer RNA, are engaged in a variety of cell processes, including gene expression, according to advances in molecular biology.

1 Feb 2023