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New method for mapping the structures of heparan sulfate sugars

Heparin, the blood-thinning drug, is used worldwide. However, to date, mapping of the fundamental sugar structures of heparin and the wider class of heparan sulfate sugars in cells has not been accomplished.

23 Mar 2020

Bacterial acid tolerance system shown to confer growth capability to enteric bacteria

The potential to proliferate under acidic conditions is crucial for bacteria. Escherichia coli, Salmonella, and other such enteric bacteria have the ability to colonize and cause disease in the intestinal tract of the host. Yet, they must fight against acidic environments in the entire process of host invasion.

23 Mar 2020

Study offers detailed molecular map of interaction patterns of GPCR and different G protein subtypes

G protein-coupled receptors (GPCRs) have crucial roles to play in cell signal transduction and can be used as vital therapeutic targets for several diseases.

20 Mar 2020

Genetically manipulating cells using synthetic materials to construct artificial structures

Researchers at the Stanford School of Engineering have designed a technique for reprogramming cells to use synthetic materials, which the team provides, to create artificial structures that can perform functions within the body.

20 Mar 2020

Multi-tissue model shows how different tissues account for various inflammatory diseases

Biological engineers from Massachusetts Institute of Technology (MIT) have developed a multi-tissue model that allows them to analyze the associations between the immune system and different organs, on a dedicated microfluidic platform embedded with human cells.

From Massachusetts Institute of Technology (MIT) 19 Mar 2020

New computer program can help map individual nerve cells in worms

A new computer program has been developed by scientists who are focused on interpreting the mechanism of the brain in high-definition and at the single-cell level of detail.

19 Mar 2020

Role of MCL1 in maintaining intestinal homeostasis

An international group of scientists from the University of Zurich, the University Hospital Zurich, Heidelberg, and Glasgow have discovered a new function of MCL1, the protein that regulates cell death.

19 Mar 2020

Regulating ion flow using a ball-and-chain mechanism

Ion channels that permit potassium and sodium ions to move in and out of cells are essential for the function of the brain and heart, and also for neuronal “firing” in the central nervous system.

19 Mar 2020

A New Imaging Technique for Mapping Forces Exerted by Cell Clusters

AZoLifeSciences talks to Ian Wong about a new imaging technique that maps forces cell clusters exert on their surroundings.

From Brown University 19 Mar 2020

IL-2's flexible structure helping the immune system

Scientists have known that interleukin-2 (IL-2), a signaling molecule, strongly influences the immune system. However, attempts to leverage its potential for therapeutic purposes have went futile due to serious side effects.

From University of California Santa Cruz 18 Mar 2020

Study finds fatty acid uptake is greater in cells that lack EHD2 protein

Several foods such as mozzarella on a pizza, the olive oil in salad dressing, or hollandaise sauce used on asparagus contain lots of fat.

18 Mar 2020

New CRISPR technology targets thousands of genes

Thanks to CRISPR-based genetic screens, researchers were able to detect genes that play a major role in lung cancer metastasis, cancer immunotherapy, sickle-cell anemia, and a host of other medical disorders.

18 Mar 2020

Study demonstrates ability of blended electrospun mat to gradually release protein

Russian scientists from the Federal Research Clinical Center of Physical-Chemical Medicine, the Moscow Institute of Physics and Technology, and Lomonosov Moscow State University have shown that it is possible to combine two incompatible components—a protein and a polymer—in one electrospun fiber.

17 Mar 2020

More efficient, cost-effective method for accurate synthesis of DNA

DNA is a genetic material that continues to survive only through replication, either naturally or synthetically. Humans require reproduction of DNA to replace damaged or old cells, but the potential to replicate DNA in a laboratory setting can allow scientists understand the disease mechanisms or the platform to develop treatments.

17 Mar 2020

Parallel neural pathways bypassing brain’s frequency control enable animals to move faster

The speed at which a person runs determines the end result, whether running to win an Olympic gold or to escape a predator.

13 Mar 2020

Biochemical, analytical high-throughput methods used to map proteome of plants

Plants play a crucial role in the survival of life on earth. They offer oxygen for breathing and food for all organisms, as well as regulate the planet’s climate. Proteins are vital in controlling all aspects of life, including plants.

13 Mar 2020

Researchers uncover a surprising property of blood stem cells

A Franco-German research team led by Prof. Michael Sieweke, from the Center for Regenerative Therapies TU Dresden and the Center of Immunology of Marseille Luminy, today uncovered a surprising property of blood stem cells: not only do they ensure the continuous renewal of blood cells and contribute to the immune response triggered by an infection, but they can also remember previous infectious encounters to drive a more rapid and more efficient immune response in the future.

13 Mar 2020

DeNovix becomes sponsor at Tufts Launchpad BioLabs

DeNovix Inc. is the newest sponsor at Tufts Launchpad | BioLabs with the placement of two key pieces of laboratory instrumentation. DeNovix has provided a CellDrop FL Automated Cell Counter and a DS-11 FX+ Spectrophotometer / Fluorometer for use by the facility’s resident companies.

From DeNovix Inc. 13 Mar 2020

Study identifies that the JNK protein is a stress sensor in synapses

Synapses are minute cell projections through which electrochemical impulses are transferred between nerves.

12 Mar 2020

Changes in cell death patterns in the nervous system could allow a species to adapt to its environment

According to research conducted in fruit flies at the Francis Crick Institute, the University of Lausanne (UNIL) and the Max Planck Institute for Chemical Ecology, zombie cells tend to develop into functional neurons when the death of neurons is stopped during brain growth.

12 Mar 2020

Cell News and Research

New method for mapping the structures of heparan sulfate sugars

Bacterial acid tolerance system shown to confer growth capability to enteric bacteria

Study offers detailed molecular map of interaction patterns of GPCR and different G protein subtypes

Genetically manipulating cells using synthetic materials to construct artificial structures

Multi-tissue model shows how different tissues account for various inflammatory diseases

New computer program can help map individual nerve cells in worms

Role of MCL1 in maintaining intestinal homeostasis

Regulating ion flow using a ball-and-chain mechanism

A New Imaging Technique for Mapping Forces Exerted by Cell Clusters

IL-2's flexible structure helping the immune system

Study finds fatty acid uptake is greater in cells that lack EHD2 protein

New CRISPR technology targets thousands of genes

Study demonstrates ability of blended electrospun mat to gradually release protein

More efficient, cost-effective method for accurate synthesis of DNA

Parallel neural pathways bypassing brain’s frequency control enable animals to move faster

Biochemical, analytical high-throughput methods used to map proteome of plants

Researchers uncover a surprising property of blood stem cells

DeNovix becomes sponsor at Tufts Launchpad BioLabs

Study identifies that the JNK protein is a stress sensor in synapses

Changes in cell death patterns in the nervous system could allow a species to adapt to its environment

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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