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Computational DNA droplet recognizes a specific combination of tumor biomarker microRNAs

The formation of aqueous droplets in macromolecules by liquid-liquid phase separation (or coacervation) is a popular topic in life sciences research. DNA is particularly interesting among the numerous macromolecules that form droplets because it is predictable and programmable, both of which are desirable properties in nanotechnology.

6 Jun 2022

Study identifies the regulatory function of non-coding 7S RNA

In human cells, a non-coding RNA molecule controls mitochondrial gene expression, according to new research published in the journal Cell. The research is the result of a collaboration between Sweden’s University of Gothenburg and Karolinska Institutet, as well as Germany’s University of Cologne.

3 Jun 2022

Researchers reveal that new compact version of Cas7-11 enzyme improves RNA editing

Cas7-11, the first CRISPR enzyme that can make precise, directed cuts to strands of RNA without hurting cells, was identified and described last year by researchers at MIT’s McGovern Institute for Brain Research.

From Massachusetts Institute of Technology (MIT) 2 Jun 2022

Researchers discover distinctive antibacterial therapy that uses visible light-activated synthetic molecular machine

Infectious-bacteria-killing molecular machines have been persuaded to reconsider their goal.

2 Jun 2022

Researchers determine intracellular antibodies to cure diseases

Mermaid Bio GmbH of Munich, Germany, and WEHI of Melbourne, Australia, recently announced cooperation to identify and develop a unique class of therapeutic candidates that modify misbehaving proteins inside cells that can cause a variety of diseases.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 1 Jun 2022

Study highlights the interaction between single-stranded DNA and the linker histone H1

Human DNA is neatly locked in place around a central disc in the tight quarters of the cell nucleus by H1 linker histone that helps shepherd DNA into the tidy chromatin fibers that make up chromosomes. The linker histone, on the other hand, is much more than a protein clip.

31 May 2022

Scientists develop powerful tools using CRISPR-Cas9 to repair genetic diseases

CRISPR has marked the beginning of a new era in genomic medicine. The popular CRISPR-Cas9 has generated plenty of potent methods for curing genetic diseases.

30 May 2022

Scientists discover a new left-handed Z-DNA technique to kill hard-to-treat tumors

An international collaboration of scientists has discovered a new technique to kill cancers that are difficult to treat, according to an article published in Nature.

30 May 2022

Researchers develop a new biochemical process to analyze plant immunity

Researchers from Germany’s Max Planck Institute for Plant Breeding Research (MPIPZ) and the University of Cologne have identified a new biochemical process that explains how immune proteins protect plants against invading microbes. Their results have been reported in Cell.

From The Max Planck Institute 27 May 2022

Scientists demonstrate how stomach stem cells switch from one state to the other upon injury

A stomach adult stem cell population can fulfill two distinct functions: either help with digestion under normal conditions or take the lead on injury response. S

26 May 2022

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Small interfering RNAs, or siRNAs, have the potential to cure tumors by targeting knocking down oncogenes that drive tumor development while avoiding the damage associated with chemotherapy.

25 May 2022

Researchers propose new methods to save the world’s most important crops

Plants are just like humans, with their ways of dealing with stress. Researchers are tracing out plants’ stress-busting methods to save one of the world’s most powerful crops from adverse climatic swings.

23 May 2022

Type I interferon may activate a potent immune response against harmful viruses

Researchers at McMaster University have discovered not only how specific viral infections potentially cause tissue damage, but also how to prevent it.

23 May 2022

New research identifies a destination for zinc chaperone protein's deliveries

Most people don't think much about zinc. But all living things need zinc for survival. This trace element helps many proteins fold into the right shapes to do their jobs.

18 May 2022

New supramolecular CRISPR–Cas9 carrier supports much effective genome editing

Clustered regularly interspaced short palindromic repeats (CRISPR) and their accompanying protein, CRISPR-associated protein 9 (Cas9), several years ago, made international news as a game-changing genome editing system.

18 May 2022

Research shows how the mitotic mechanism locate plant cell using moss plant

Cells must divide many times before a new plant can grow from seed.

10 May 2022

Study shows new potential target for CAR T cells to inhibit solid tumors

CAR T therapy, or chimeric antigen receptor T-cell therapy, has revolutionized the treatment of some blood cancers, allowing patients with relapsed or refractory disease to live longer and better lives.

10 May 2022

New open-source tool automates RNA analysis, likely to encourage research and drug development

Scripps Research scientists have introduced a new software tool for examining RNA (ribonucleic acid) molecules, which play a variety of important roles in living things.

10 May 2022

Study shows how nanotechnology may help for structural research of RNA molecules

Humans live in a world created and managed by RNA—the genetic molecule DNA’s equally important sibling.

3 May 2022

Scientists get a clearer and more accurate image of proteins

Proteins are among the most significant and diverse biomolecules found in living organisms. These strings of amino acids, which take on complex 3-dimensional structures, are required for tissue growth and maintenance, the activation of thousands of biochemical events, and the immune system’s defense against invaders.

3 May 2022

Molecule News and Research

Computational DNA droplet recognizes a specific combination of tumor biomarker microRNAs

Study identifies the regulatory function of non-coding 7S RNA

Researchers reveal that new compact version of Cas7-11 enzyme improves RNA editing

Researchers discover distinctive antibacterial therapy that uses visible light-activated synthetic molecular machine

Researchers determine intracellular antibodies to cure diseases

Study highlights the interaction between single-stranded DNA and the linker histone H1

Scientists develop powerful tools using CRISPR-Cas9 to repair genetic diseases

Scientists discover a new left-handed Z-DNA technique to kill hard-to-treat tumors

Researchers develop a new biochemical process to analyze plant immunity

Scientists demonstrate how stomach stem cells switch from one state to the other upon injury

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Researchers propose new methods to save the world’s most important crops

Type I interferon may activate a potent immune response against harmful viruses

New research identifies a destination for zinc chaperone protein's deliveries

New supramolecular CRISPR–Cas9 carrier supports much effective genome editing

Research shows how the mitotic mechanism locate plant cell using moss plant

Study shows new potential target for CAR T cells to inhibit solid tumors

New open-source tool automates RNA analysis, likely to encourage research and drug development

Study shows how nanotechnology may help for structural research of RNA molecules

Scientists get a clearer and more accurate image of proteins

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