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Study shows human genome regulates the early development of organs

A team of researchers has identified how the human genome regulates the development of several organs that are crucial to human life.

From The University of Manchester 11 Aug 2020

New study may offer a novel, potential target for treating breast cancer

According to researchers, G-quadruplexes have been demonstrated to play a crucial role in specific types of breast cancer for the first time.

5 Aug 2020

Genome editing technologies can help understand disease-associated genetic mutations

Scientists have developed novel genome-editing technology that could help understand disease-related genetic mutations based on C-to-G single base variations.

27 Jul 2020

Researchers identify genetic variants that predispose to cancer

The concept that cancer development is “monitored and prevented” by the immune system was first suggested at the beginning of the previous century.

26 Jun 2020

Study sheds light on DNA sculpting properties of enigmatic protein

Sometimes, when something is broken, the first step to fixing it is to break it even more. In a recent example, scientists seeking to understand the mechanism of a DNA-repairing enzyme have discovered that the molecule performs its functions by first marking and then further breaking damaged DNA.

22 Jun 2020

Study sheds light on the reproductive role of 'dark matter' DNA

Researchers from the Okinawa Institute of Science and Technology Graduate University have shed light on the reproductive role of 'dark matter' DNA - non-coding DNA sequences that previously seemed to have no function.

19 Jun 2020

Genome rewiring could help explain evolution of multi-cellular organisms

InsideOutBio expert Dr Alan Herbert has explained a pioneering research in a paper recently published online by the Royal Society Open Science journal.

9 Jun 2020

gnomAD Consortium releases first set of discoveries on human genetic variation

For the last eight years, the Genome Aggregation Database Consortium (and its predecessor, the Exome Aggregation Consortium, or ExAC), has been working with geneticists around the world to compile and study more than 125,000 exomes and 15,000 whole genomes from populations around the world.

29 May 2020