Dementia News and Research

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Dementia is not a specific disease. It is a descriptive term for a collection of symptoms that can be caused by a number of disorders that affect the brain. People with dementia have significantly impaired intellectual functioning that interferes with normal activities and relationships. They also lose their ability to solve problems and maintain emotional control, and they may experience personality changes and behavioral problems, such as agitation, delusions, and hallucinations.

Researchers analyze and demonstrate how organelles divide into cells

The research, headed by Professor Michael Schrader of the University of Exeter, looked at peroxisome dynamics and discovered new ways for them to divide.

From University of Exeter 10 Jun 2022

Researchers use gene-editing in tomatoes to boost vitamin D content

Researchers employed gene editing to switch off a specific component in the tomato plant’s DNA, which led to an increase in provitamin D3 in both the fruit and leaves. After that, UVB light was used to convert it to vitamin D3.

27 May 2022

Study shows serum-derived extracellular vesicles may help in diagnosing amyloidosis

Amyloidosis is a term used to describe a group of diseases defined by the formation of insoluble proteins called amyloids outside of cells as a result of misfolding and aggregation of soluble proteins.

12 May 2022

Stress helps remove the formation of toxic proteins in dementia

Recently, researchers have discovered a novel method that could help avoid the formation of protein tangles, which are typical in dementia.

12 May 2022

Little-known protein may play a role in frontotemporal lobar degeneration

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

21 Apr 2022

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

The loss of functional neurons in the brain is a characteristic of Alzheimer’s disease. What, on the other hand, is the source of this loss?

21 Apr 2022

What does Creativity and Innovation Look Like In Science?

For World Creativity and Innovation Day, we asked leading experts within the life sciences industry 'What does creativity and innovation look like to you within science?'.

21 Apr 2022

Study shows how peptide inhibitor helps to treat Alzheimer’s and Huntington’s disease

According to the Alzheimer’s Association, around 11% of the population, comprising 65-year old and above—in the United States has been diagnosed with Alzheimer’s disease (AD), the most prevalent form of dementia that causes memory loss and cognitive impairment.

19 Apr 2022

Critical signaling pathways in immune cells could reduce Alzheimer’s progression

According to Weill Cornell Medicine researchers, inhibiting a critical signaling route in brain-resident immune cells may reduce brain inflammation and hence halt the progression of the disease in Alzheimer’s and other neurodegenerative disorders.

15 Apr 2022

A mitochondrial uncoupler prevents sarcopenic obesity in elderly mice

A recently discovered chemical compound helped elderly mice with obesity lose fat and weight, add muscle and strength, reduce age-related inflammation and increase physical activity, a new study shows.

7 Apr 2022

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

If we want to enhance our knowledge and treatment of Alzheimer’s disease, we need to identify genetic risk factors.

7 Apr 2022

Experts investigate the activity of genes in dog brain tissues

Upon examining the gene activity in dog brain tissues, it was revealed that a major part is active in every animal.

23 Mar 2022

Transcriptomic analysis of Alzheimer's patients reveals early organelle dysfunction in astrocytes

An international group of researchers led by the UAB analyzed the genes that are expressed in neurons and astrocytes based on data from 800 individuals and compared what happens in Alzheimer's patients and in people without diagnosed dementia.

21 Mar 2022

Study identifies two types of brain cells that play a key role in creating memories

In a study led by Cedars-Sinai, researchers have discovered two types of brain cells that play a key role in dividing continuous human experience into distinct segments that can be recalled later.

8 Mar 2022

Research points to a common thread linking diverse neurodegenerative diseases

Take a cell-deep tour of a brain afflicted with Alzheimer's disease, and you will find minuscule clumps of protein that seem suspicious. Ever since the 1980s, when neuroscientists began identifying these protein tangles, researchers have discovered that other brain diseases have their own tangled-protein signatures.

7 Mar 2022

Novel molecular pathway shared by ALS and frontotemporal dementia identified

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

1 Mar 2022

New study uncovers potential driver of Parkinson’s disease

Parkinson's disease may be driven in part by cell stress-related biochemical events that disrupt a key cellular cleanup system, leading to the spread of harmful protein aggregates in the brain, according to a new study from scientists at Scripps Research.

24 Feb 2022

Dementia News and Research

Researchers analyze and demonstrate how organelles divide into cells

Researchers use gene-editing in tomatoes to boost vitamin D content

Study shows serum-derived extracellular vesicles may help in diagnosing amyloidosis

Stress helps remove the formation of toxic proteins in dementia

Little-known protein may play a role in frontotemporal lobar degeneration

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

What does Creativity and Innovation Look Like In Science?

Study shows how peptide inhibitor helps to treat Alzheimer’s and Huntington’s disease

Critical signaling pathways in immune cells could reduce Alzheimer’s progression

A mitochondrial uncoupler prevents sarcopenic obesity in elderly mice

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

Experts investigate the activity of genes in dog brain tissues

Transcriptomic analysis of Alzheimer's patients reveals early organelle dysfunction in astrocytes

Study identifies two types of brain cells that play a key role in creating memories

Research points to a common thread linking diverse neurodegenerative diseases

Novel molecular pathway shared by ALS and frontotemporal dementia identified

New study uncovers potential driver of Parkinson’s disease

Study discovers common genetic factors between depression and Alzheimer’s disease

UCI biologists discover how a gene variant protects against Alzheimer's disease

Scientists use genetically informed brain atlases to identify hundreds of genomic loci

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