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Three new COVID-19 variants can evade antibodies that act against original virus

New research at Washington University School of Medicine in St. Louis indicates that three new, fast-spreading variants of the virus that cause COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic.

5 Mar 2021

Engineered safety switch reduces CAR-T immunotherapy-related side effects

UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the severity of treatment side effects that sometimes occur.

5 Mar 2021

Ultrasonic cleaning can clean food more effectively than current washing methods

New research has demonstrated that mild streams of water transporting sound and tiny air bubbles can remove bacteria from salad leaves more effectively.

3 Mar 2021

Researchers find effective combination of therapies for managing mitochondrial disease

Researchers have demonstrated how one combination of therapies may be beneficial for patients with mitochondrial respiratory chain disorders.

3 Mar 2021

New approach could speed the search for promising therapies

Assessing a drug compound by its activity, not simply its structure, is a new approach that could speed the search for COVID-19 therapies and reveal more potential therapies for other diseases.

2 Mar 2021

New technique reveals the tricks that cancer cells use to avoid immunotherapies

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients--across cancer types--do not respond, and in most cases, scientists are at a loss as to why.

2 Mar 2021

Protein kinases may offer a solution to treat HIV patients with immunodeficiency

A new study indicates that protein kinases, which initiate the process that erodes the body’s immunity, significantly contribute to the immunodeficiency in HIV patients. Drugs that block these protein kinases may offer a solution to treating HIV patients whose immunity is not restored by antiretroviral therapy.

2 Mar 2021

Scientists gain new insights into ribosome formation to identify potential drug targets

Ribosome formation is viewed as a promising potential target for new antibacterial agents. Researchers from Charité - Universitätsmedizin Berlin have gained new insights into this multifaceted process.

2 Mar 2021

Increased levels of OAS1 protein may reduce the severity of COVID-19

Researchers at the Lady Davis Institute (LDI) at the Jewish General Hospital have discovered that increased levels of the protein OAS1 are associated with reduced mortality and less severe disease requiring ventilation among patients with COVID-19.

1 Mar 2021

Researchers identify a type of RNA as therapeutic target for Huntington's treatment

Huntington's disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations.

24 Feb 2021

Compounds from marine-derived fungus may protect cells from paraquat

Biologically active compounds from the marine fungus Penicillium dimorphosporum protect cells from paraquat, the highly toxic herbicide with no remedy, and might enhance the action of some drugs.

24 Feb 2021

Cryogenic electron microscopy reveals shape of glutamate transporters involved in neurological diseases

An international research team has uncovered the shape of the glutamate transporter and helps explain how the human brain cells interact with each other.

18 Feb 2021

Study reveals novel antibody binding implicated in liver and breast cancer

In the field of structural biology, certain molecules are so uncommon that they can only be captured with a special set of tools.

18 Feb 2021

Study identifies how CTLA-4 blockade can disable suppressive immune cells to aid tumor destruction

A Ludwig Cancer Research study has identified a novel mechanism by which a type of cancer immunotherapy known as CTLA-4 blockade can disable suppressive immune cells to aid the destruction of certain tumors.

18 Feb 2021

Research links blood-clotting protein with CNS B-cell lymphoma growth

In people with central nervous system (CNS) lymphoma, cancerous B cells--a type of white blood cell--accumulate to form tumors in the brain or spinal cord, often in close proximity to blood vessels.

18 Feb 2021

Testing for inherited genes can help understand future cancer risk in pediatric patients

Because cancers in children are rare, many details about their biology remain unknown. In the field of cancer genetics, there's a limited understanding of how inherited genetic changes may contribute to the formation and growth of tumors.

17 Feb 2021

Study suggests a way to improve immunotherapy by altering immune cells’ access to sugar

Cancer cells and immune cells share something in common: They both love sugar. Sugar is an important nutrient. All cells use sugar as a vital source of energy and building blocks. For immune cells, gobbling up sugar is a good thing, since it means getting enough nutrients to grow and divide for stronger immune responses. But cancer cells use sugar for more nefarious ends.

17 Feb 2021

Combining cholesterol-lowering medications and lifestyle interventions may yield better benefits

Combining healthy lifestyle interventions reduces heart disease through beneficial effects on different lipoproteins and associated cholesterols, according to a study published February 9 in eLife.

17 Feb 2021

New understanding of tumor microenvironment could help enhance immunotherapy

A paper published today in Nature shows how chemicals in the areas surrounding tumors--known as the tumor microenvironment--subvert the immune system and enable cancer to evade attack. These findings suggest that an existing drug could boost cancer immunotherapy.

From University of Pittsburgh 16 Feb 2021

Machine learning approach to identify drugs that could be repurposed to fight Covid-19

When the Covid-19 pandemic struck in early 2020, doctors and researchers rushed to find effective treatments.

16 Feb 2021

Drugs News and Research

Three new COVID-19 variants can evade antibodies that act against original virus

Engineered safety switch reduces CAR-T immunotherapy-related side effects

Ultrasonic cleaning can clean food more effectively than current washing methods

Researchers find effective combination of therapies for managing mitochondrial disease

New approach could speed the search for promising therapies

New technique reveals the tricks that cancer cells use to avoid immunotherapies

Protein kinases may offer a solution to treat HIV patients with immunodeficiency

Scientists gain new insights into ribosome formation to identify potential drug targets

Increased levels of OAS1 protein may reduce the severity of COVID-19

Researchers identify a type of RNA as therapeutic target for Huntington's treatment

Compounds from marine-derived fungus may protect cells from paraquat

Cryogenic electron microscopy reveals shape of glutamate transporters involved in neurological diseases

Study reveals novel antibody binding implicated in liver and breast cancer

Study identifies how CTLA-4 blockade can disable suppressive immune cells to aid tumor destruction

Research links blood-clotting protein with CNS B-cell lymphoma growth

Testing for inherited genes can help understand future cancer risk in pediatric patients

Study suggests a way to improve immunotherapy by altering immune cells’ access to sugar

Combining cholesterol-lowering medications and lifestyle interventions may yield better benefits

New understanding of tumor microenvironment could help enhance immunotherapy

Machine learning approach to identify drugs that could be repurposed to fight Covid-19

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