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Researchers identify suitable biocatalyst for designing COVID-19 vaccine

The chemical substance class of nucleosides is attracting a great deal of interest, and this can be attributed to the ongoing COVID 19 pandemic.

17 Dec 2020

Study: DOT1L enzyme is essential for humoral immune responses

Communication, serendipity and an enzyme called DOT1L have all combined to produce some exciting findings into the immune system's B cells and T cells by two groups of Monash Biomedicine Discovery Institute (BDI) scientists.

17 Dec 2020

Researchers discover genetic variants of host proteins involved in SARS-CoV-2 infection

Like all viruses, the novel coronavirus is dependent on help from the human host cell. Proteins are the functional units of the cell and enable the virus to enter the host cell or help the virus to replicate.

17 Dec 2020

Researchers test effects of weedkiller on wildlife

Prolonged exposure to environmentally relevant concentrations of the weedkiller Roundup causes significant harm to keystone species according to new research at the University of Birmingham.

16 Dec 2020

Using genetic engineering to grow synthetic livers

News-Medical talks to Dr. Mo Ebrahimkhani about his research using genetic engineering together with a machine-learning algorithm to mature a lab-grown 'designer liver organoid'.

From University of Pittsburgh 15 Dec 2020

New combination therapy could be effective in treating aggressive cancers with common mutations

Scientists have long known that therapies that target the cancer-driving MAPK pathway are only effective in a handful of cancers with specific mutations in a cancer gene called BRAF, and these cancers that initially respond to the therapy often end up developing resistance to the treatment, resulting in relapse for many patients.

15 Dec 2020

New analysis technique could pave way for major breakthroughs in immunotherapy

In a new study, researchers at Uppsala University have been able to show differences in how Rituximab, a monoclonal antibody drug, interacts with the blood of healthy individuals compared to patients with chronic lymphatic leukaemia.

14 Dec 2020

Study elucidates genes responsible for Glioblastoma invasiveness

One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into the normal brain tissue.

14 Dec 2020

Olefins formed by light-driven catalyst can help produce drugs, agrochemicals

Taking a cue from light-sensing bacteria that live close to hot oceanic vents, synthetic chemists from Rice University have identified a mild process to produce useful hydrocarbons, called alkenes, or olefins.

11 Dec 2020

New antibiotic can help treat drug-resistant pathogens

Researchers from Johns Hopkins University and Medicine have designed a potential new antibiotic for a pathogen that is highly resistant to drugs and is often lethal to individuals suffering from lung diseases, including cystic fibrosis.

11 Dec 2020

Revolutionary CRISPR-based genome editing system treatment destroys cancer cells

Researchers at Tel Aviv University have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers.

11 Dec 2020

Scientists aim to treat and prevent disease by understanding exercise benefits

A top exercise researcher and colleagues at the University of Virginia School of Medicine have launched an ambitious effort to understand the whole-body benefits of exercise so that doctors can use that information to prevent and treat disease.

11 Dec 2020

A genetic shortcut to help visualize proteins at work

A group at Gladstone Institutes and UC San Francisco (UCSF) has demonstrated that a large-scale and systematic genetic approach can indeed yield reliable and detailed information on the structure of protein complexes.

11 Dec 2020

Research shows how microbubbles can be used to administer potent cancer drugs

New research has shown how microbubbles carrying powerful cancer drugs can be guided to the site of a tumour using antibodies.

11 Dec 2020

Novel amplification-free rapid SARS-CoV-2 nucleic acid detection platform based on HC-FIA

The COVID-19 pandemic has highlighted the need for rapid and accurate nucleic acid detection at the point of care.

11 Dec 2020

Study shed light on how genes affect the risk for coronary artery disease

Researchers at the University of Virginia have shed light on how our genes affect our risk for coronary artery disease, the most common form of heart disease.

11 Dec 2020

Scientists use honey bee peptide to design RBC carriers that deliver therapeutic proteins

Most often, protein therapies are more selective and potent toward their biochemical targets when compared to other types of medicines, specifically small molecules.

10 Dec 2020

Genetically modified tomato can provide a new source of Parkinson’s disease drug

L-DOPA is a drug used for treating Parkinson’s disease, and now researchers have created a tomato that is enriched with this drug. This innovation could lead to a new, inexpensive source of one of the most essential medicines in the world.

10 Dec 2020

Appendiceal cancer among young patients harbors a distinct biology, shows study

The first study to compare molecular landscapes of early-onset and late-onset appendiceal cancer has revealed distinct non-silent mutations in the tumors of younger patients, setting the stage for the development of potential therapeutic advances for this rare disease.

From Vanderbilt University 10 Dec 2020

New microrobots show promise for future medical applications

Cancer drugs have side effects, so for many years, scientists have been exploring ways to transport the active substances to a tumour in the body as precisely as possible. That is the only place that drugs should take effect.

9 Dec 2020