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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Exploring the Genetic effects of Chernobyl Radiation

In this interview, AZoLifeSciences speaks to researchers from the National Cancer Institute about their latest research that investigated the genetic effects of Chernobyl radiation.

From National Cancer Institute (NCI) 13 May 2021

Increased expression of DUSP16 molecule leads to cancer chemoresistance

Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cancer cells in the body. It is a systemic treatment where drugs travel throughout the body and destroy cancer cells that have spread (metastasized) to parts of the body far away from the original (primary) tumour.

28 Apr 2021

Chemical biomarker levels reflect varying severity of COVID-19 symptoms

Varying severity of COVID-19 symptoms in patients is reflected by levels of a chemical biomarker in their body which scientists say could be used to better manage treatments and other interventions, including vaccinations.

20 Apr 2021

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Scientists from Buck Institute have identified and are now developing an innovative, non-invasive biomarker test that could help quantify and track the performance of senolytics—a class of drugs that selectively destroy senescent cells.

5 Apr 2021

Fish oil provides health benefits based on the genetic makeup

Fish oil supplements are a billion-dollar industry built on a foundation of purported, but not proven, health benefits. Now, new research from a team led by a University of Georgia scientist indicates that taking fish oil only provides health benefits if you have the right genetic makeup.

From University of Georgia 26 Mar 2021

Low representation of minority groups in genomic databases may impact therapy selection

Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology.

22 Mar 2021

Study shows beneficial effects of gene therapy can be observed even after several decades

A new study shows that the advantageous effects of gene therapy can be observed several decades after the body clears the transplanted blood stem cells.

From University College London 18 Mar 2021

Study reveals substantial difference in selection and timing of genetic tests for non-small-cell lung cancer

During biomarker testing, certain disease-associated molecules are examined to estimate the progression of a disease and its response to treatments.

17 Mar 2021

Gut mycobiome correlates with metabolic outcomes in response to diet

Studies of the microbiome in the human gut focus mainly on bacteria. Other microbes that are also present in the gut -- viruses, protists, archaea and fungi -- have been largely overlooked.

8 Mar 2021

New gel electrophoresis method allows rapid diagnosis of biomarkers by mass spectrometry

Polyacrylamide gel electrophoresis is a technique that allows high-resolution isolation of proteins separated from biological specimens.

22 Feb 2021

Electrochemical sensor for rapid detection of multiple sepsis biomarkers in whole blood

Many life-threatening medical conditions, such as sepsis, which is triggered by blood-borne pathogens, cannot be detected accurately and quickly enough to initiate the right course of treatment.

15 Feb 2021

Study finds the brain is changed by caffeine in utero

New research finds caffeine consumed during pregnancy can change important brain pathways that could lead to behavioral problems later in life.

10 Feb 2021

Unique proteomics-based technology can help diagnose breast cancer more accurately

Breast cancer could be identified more precisely than existing methods using blood specimens and exclusive proteomics-based technology.

28 Jan 2021

TBI: Increased levels of immune cells promote inflammation that may worsen brain damage

Immediately after a traumatic brain injury and as long as one year later, there are increased levels of immune cells called ILCs in the brain promoting inflammation, which can worsen brain damage, scientists report.

27 Jan 2021

Continuous in vitro monitoring could lead to faster, more effective treatments for chronic conditions

A world-first discovery by researchers at Monash University and The University of Queensland could lead to faster and more effective treatments for chronic health complications, such as cardiovascular disease and cancer, with 'fluorescent' in vivo biosensors.

27 Jan 2021

Study: Vegan diet has broad effect on children's metabolism

The study concludes that vegan diet has a broad effect on children's metabolism. Serum biomarker levels for vitamins A and D, cholesterol forms and essential amino acids were significantly lower in children on vegan diet compared to age-adjusted omnivores.

22 Jan 2021

Biomarker News and Research

Exploring the Genetic effects of Chernobyl Radiation

Increased expression of DUSP16 molecule leads to cancer chemoresistance

Chemical biomarker levels reflect varying severity of COVID-19 symptoms

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Fish oil provides health benefits based on the genetic makeup

Low representation of minority groups in genomic databases may impact therapy selection

Study shows beneficial effects of gene therapy can be observed even after several decades

Study reveals substantial difference in selection and timing of genetic tests for non-small-cell lung cancer

Gut mycobiome correlates with metabolic outcomes in response to diet

New gel electrophoresis method allows rapid diagnosis of biomarkers by mass spectrometry

Electrochemical sensor for rapid detection of multiple sepsis biomarkers in whole blood

Study finds the brain is changed by caffeine in utero

Unique proteomics-based technology can help diagnose breast cancer more accurately

TBI: Increased levels of immune cells promote inflammation that may worsen brain damage

Continuous in vitro monitoring could lead to faster, more effective treatments for chronic conditions

Study: Vegan diet has broad effect on children's metabolism

Targeting RNA splicing can trigger antiviral immune pathways in triple-negative breast cancers

Protein phosphatase inhibition could contribute to the treatment of cancer, other diseases

Proteogenomic study may lead to more effective treatments for head and neck squamous cell carcinoma

Sugar-binding protein could serve as a useful biomarker for patients at risk of sepsis

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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