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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

Unboxing the mystery genome black box with the DNA sequencing method

Researchers from the University of Cambridge have described a new DNA sequencing technique that can find out where and how small molecule drugs interact with the targeted genome in a study that was published in the journal Nature Biotechnology.

26 Jan 2023

The 12-hour cyclic gene activity abnormalities in schizophrenic brains

The first proof of 12-hour cycles of gene activity in the human brain is presented by researchers at the University of Pittsburgh School of Medicine in the United States.

From University of Pittsburgh 26 Jan 2023

Enhancing the efficacy of CRISPR/Cas9 and related methods

The effectiveness of molecular genetic techniques like CRISPR/Cas9 and related systems has been significantly improved, and their range of applications has been expanded, by researchers from the Department of Developmental Biology/Physiology at the Centre for Organismal Studies of Heidelberg University.

26 Jan 2023

Study sheds new light on a lifestyle switch that occurs in marine bacteria

Scientists have detailed a lifestyle switch that occurs in marine bacteria, where they change from coexisting with algae hosts in a mutually beneficial interaction to suddenly killing them.

25 Jan 2023

New genetic condition that raises vulnerability to opportunistic infections

An international consortium co-led by Vanderbilt University Medical Center immunogeneticist Rubén Martínez-Barricarte, PhD, has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including life-threatening fungal pneumonia.

24 Jan 2023

New computational tool for long-read RNA sequencing

An evolving RNA molecule can be cut and joined, or spliced, in various ways on the path from gene to protein before being translated into a protein. Using a technique called alternative splicing, multiple proteins can be encoded by a single gene.

24 Jan 2023

Island populations may be a lot tougher and more complex than previously thought

It's often assumed that island plant and animal populations are just the simple, fragile cousins of those on the mainland. But now, researchers from Japan have discovered that island populations may be a lot tougher and more complex than previously thought.

23 Jan 2023

Discovery of the gene responsible for rare childhood cancer

The first thorough genetic map of sarcomas, created by research led by Omico, the Garvan Institute of Medical Research, and UNSW Sydney, has revealed several genes that contribute to a rare childhood cancer.

20 Jan 2023

Tumor progression after immunotherapy: Molecular pathways revealed

The University of Michigan’s Rogel Cancer Center researchers discovered a mechanism that explains why a subset of patients’ tumors grows rather than shrink when treated with immunotherapy.

20 Jan 2023

New center to assist in understanding non-coding cancer genome

The MacMillan Center for the Study of the Non-Coding Cancer Genome (MCSNCG) was officially launched by the New York Genome Center (NYGC) on January 18th, 2023.

19 Jan 2023

Benefits of Finnish health research environment for genomic research

New findings from the FinnGen study illustrate the clear advantages of the Finnish health research environment for genomic research.

19 Jan 2023

Molecular mechanism behind microtubule dynamics in R. contractilis

Raphidocystis contractilis belongs to Heliozoa, a group of eukaryotes that is generally seen in brackish, fresh, and seawater.

19 Jan 2023

Blending multiple maps uncover new genetic causes of blindness

In a new study, Ran Elkon and Ruth Ashery-Padan of Tel Aviv University, Israel, and colleagues discovered a new genetic risk factor for adult-onset macular degeneration (AMD) by combining a map of gene regulatory sites with disease-associated loci.

18 Jan 2023

Potential to rectify various disease-causing mutations enhanced by CRISPR-based enzymes

Designing genome editing strategies for each patient’s mutation would be impractical and expensive because many genetic diseases are induced by diverse mutations spread across an entire gene.

18 Jan 2023

Using fungi to transform ocean plastic waste into key pharmaceutical components

Research on fungi underway at the University of Kansas has helped transform tough-to-recycle plastic waste from the Pacific Ocean into key components for making pharmaceuticals.

18 Jan 2023

New toolkit enables researchers to map an individual’s RNA data to a much richer reference

Examining the gene expression of a person needs mapping the RNA landscape to a standard reference. This is done to gain an understanding of the degree to which genes are “turned on” and execute the functions in the body.

From University of California Santa Cruz 18 Jan 2023

Role of clonal hematopoiesis as a broad driver of atherosclerosis

A group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), collaborating with institutions in the USA, has shown that acquired mutations in the gene encoding the protein p53 contribute to the onset of atherosclerotic cardiovascular disease.

18 Jan 2023

Interpretable framework to investigate the spatial organization of cells

In cells that are similar in form and function throughout tissues and organs, genes that are activated and expressed produce patterns. Identifying these patterns increases the understanding of cells, which could lead to the discovery of disease mechanisms.

18 Jan 2023

Detecting the extent of natural selection over time

Institut Pasteur, Université Paris Cité, the CNRS, and the Collège de France researchers have employed paleogenomics to trace 10,000 years of human immune system evolution. They examined the genomes of over 2,800 individuals who lived in Europe over the past 10 millennia.

From Institut Pasteur 18 Jan 2023

Grasping how a biological pathway causes stem cells to regenerate or die

According to a recent study conducted by Cedars-Sinai and the University of California, San Francisco (UCSF), altering a cellular process can cause stem cells, which are the cells that give rise to all other types of body cells, to either die or regenerate.

18 Jan 2023