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Producing New Antibiotics Through Gene Editing

In this interview, we speak to Professor Jason Micklefield about his latest research that may be able to produce new antibiotics through gene-editing technologies.

From The University of Manchester 24 Jan 2022

Study findings greatly expand the ability to engineer long-range genome edits

Researchers discovered the potential of CRISPR, a tool used by bacteria to defend themselves against viral intruders, nearly a decade ago.

24 Jan 2022

Researchers develop a high-throughput test to detect DNA repair factors

The DNA in every human cell is subjected to thousands of insults and injuries on a daily basis.

21 Jan 2022

Researchers develop a three-dimensional, fully dynamic kinetic model of a living minimal cell

Scientists report that they have built a living "minimal cell" with a genome stripped down to its barest essentials – and a computer model of the cell that mirrors its behavior.

21 Jan 2022

Stanford study reveals how ribosomes may contribute to age-related diseases

Aging leads to a decline in cellular fitness and loss of optimal protein function. Many age-related ailments, including Alzheimer's and Parkinson's diseases, are caused by protein aggregation, a result of errors in protein folding.

20 Jan 2022

IL-6 regulates cartilage regeneration in joints and growth plates, says study

The IL-6 protein family has a poor reputation for promoting inflammation, arthritis, autoimmune disease, and even cancer.

20 Jan 2022

Study identifies respiratory syncytial viral protein that mediates RSV-induced autophagy

A viral protein might contain information that could be used to avoid pneumonia due to the body’s overactive response to respiratory viruses, such as COVID-19.

20 Jan 2022

Researchers discover a molecular mechanism linked with cholesterol movement

A team of researchers from the Universitat de Barcelona (UB) discovered a mechanism associated with the movement of cholesterol within cells.

From University of Barcelona 20 Jan 2022

Study examines cadmium’s toxicological effect on the immune response and biomineralization of larval flounder

Acidification of seawater poses a significant hazard to both calcifying and non-calcifying marine species, primarily impacting the immune system and biomineralization.

20 Jan 2022

Scientists discover “resistance gene” in harmful E. coli bacteria

Researchers have discovered a gene that makes E. coli bacteria resistant to antibiotics, effectively leading to better treatment for people across the globe.

20 Jan 2022

New discovery offers insight into how cells maintain the integrity of DNA

Researchers from Case Western Reserve University have identified a new mechanism by which a protein known for repairing damaged DNA also protects the integrity of DNA by preserving its structural shape.

19 Jan 2022

Researchers discover a gene variant that protects against severe COVID-19 infection

An international metastudy led by researchers at Karolinska Institute in Sweden has identified a specific gene variant that protects against severe COVID-19 infection.

17 Jan 2022

Risk linked to coronary arteriosclerosis may be explained by changes in gene networks

Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body.

17 Jan 2022

Researchers identify new potential drug target that may block SARS-CoV-2 infection

In the quest for new treatments for COVID-19, a team led by researchers at UC San Francisco has identified a new potential drug target that may block infection by SARS-CoV-2. The protein, called BRD2, regulates the ACE2 receptor, which the novel coronavirus relies on to gain entry to its host's cells.

17 Jan 2022