Molecular & Structural Biology

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New technique shows how tRNA folding changes help to treat RNA-linked diseases

Researchers have developed a novel technique to analyze the composition and quantity of “transfer RNAs, which are tiny, chemically modified RNAs involved in protein synthesis.

From Penn State University 1 Jul 2022

Researchers examine ancient microbes to find life beyond earth

Researchers have reproduced what life was like for some of the oldest species on Earth using light-capturing proteins found in living microorganisms. These initiatives may enable everyone to spot life in distant worlds, whose atmospheres mirror the pre-oxygen planet more closely.

1 Jul 2022

Study shows how new single-cell RNA-sequencing helps to analyze gene expression

One of the most crucial techniques for examining biological activity in cells is single-cell RNA sequencing, but it is constrained by the possibility that the data it produces may be inaccurate.

From Tokyo University of Science 1 Jul 2022

Researchers use nanopore-based DNA computing technology to detect cancer

The cancer type cholangiocarcinoma, often known as bile duct cancer, is characterized by a high fatality rate.

1 Jul 2022

New biomedical research tool may help advance molecular diagnostics and drug discovery

A new biomedical research tool that enables scientists to measure hundreds of functional proteins in a single cell could offer new insights into cell machinery.

30 Jun 2022

Study reveals how amphioxus model analyze the genesis and vertebrates evolution

The two rounds of whole-genome duplication that occurred throughout the evolution of vertebrates were followed by functional divergence in terms of regulatory circuits as well as gene expression patterns.

27 Jun 2022

Research sheds light on innovative techniques to improve drugs for diseases

In a paper that was just published in Science, scientists from Sweden’s Karolinska Institutet and SciLifeLab explain how they were able to enhance a protein’s capacity to repair oxidative DNA damage while also giving the protein a new role.

27 Jun 2022

Lipid nanoparticles successfully stopped the emergence and development of tumors cells, a new study reveals

UT Southwestern researchers have developed nanoparticles that can penetrate the physical barriers that surround tumors and reach cancer cells.

27 Jun 2022

Human cells absorb less protein from plant-based meat than from chicken

Protein-rich plants, like soybeans, are common ingredients, but it is unknown how much of the nutrient gets absorbed in human cells.

27 Jun 2022

Genetic mutations allow great development of TB-causing bacteria

According to a study published today in eLife, scientists found how the bacterium that induces tuberculosis (TB) could quickly adapt in response to new environments.

27 Jun 2022

Researchers discover a way for detecting resistance-encoding genes in bacteria

Chalmers University of Technology researchers have devised a method for detecting certain bacterial genes that encode resistance using conventional microscopes, which are already used to diagnose TB in low-income countries.

27 Jun 2022

Researchers capture a new high-resolution view of the rabies virus

Around 59,000 individuals are shockingly killed by the rabies virus each year, and several of them are children. Some victims, particularly children, discover they have been exposed after it is too late.

20 Jun 2022

Scientists restructure the genome of E. coli using fragments extracted from mummy

An international group led by McMaster University researchers, in partnership with the University of Paris Cité, has recognized and reconfigured the first ancient genome of E. coli using fragments derived from a 16th-century mummy’s gallstone.

17 Jun 2022

New insights into early embryo development and origin of disease

The biochemical signals that determine the formation of the body pattern in the primate embryo have been found by scientists. This will direct research into human birth abnormalities and pregnancy loss.

17 Jun 2022

Discovery may reveal new ways to control plant growth

Understanding how plants process light is key to improving crop yields. Light helps plants know when to grow and flower at the right time.

15 Jun 2022

OTUD3 shows opposing effects in innate immunity to RNA and DNA viruses

The identification of pathogen-associated molecular patterns (PAMPs) by pattern-recognition receptors (PRRs) is the first step in initiating an immune response to viral infection.

13 Jun 2022

ZDHHC18-mediated MDH2 palmitoylation upholds mitochondrial respiration and boosts ovarian cancer malignancy

To drive anabolic processes, epithelial ovarian cancer (EOC) is heavily reliant on the tricarboxylic acid (TCA) cycle and oxidative phosphorylation.

13 Jun 2022

A signaling molecule can make plants more resistant to flooding, research shows

Extreme weather phenomena are on the rise worldwide, including frequent droughts and fires. Floods are also a clear consequence of climate change.

13 Jun 2022

Researchers utilize AI to reveal hitherto unknown 3D structures in rotavirus spike protein

The three types of rotavirus that cause gastroenteritis in individuals, known as groups A, B, and C, are the most well-known and afflict predominantly youngsters.

10 Jun 2022

Scientists discover that most synonymous mutations are strongly harmful

University of Michigan scientists reveal that most synonymous mutations are severely damaging in a study published in Nature that entailed genetic manipulation of yeast cells in the lab.

9 Jun 2022