Molecular & Structural Biology

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Little-known protein may play a role in frontotemporal lobar degeneration

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

21 Apr 2022

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

The loss of functional neurons in the brain is a characteristic of Alzheimer’s disease. What, on the other hand, is the source of this loss?

21 Apr 2022

New protective mechanism against non-alcoholic fatty liver disease identified

Non-alcoholic fatty liver disease (NAFLD), commonly known as fatty liver disease, is a prevalent disease frequently seen in obese people. Having high fat content in the liver is detrimental as it is strongly associated with severe health problems like diabetes, high blood pressure, and liver cancer.

20 Apr 2022

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

All modern organisms fall into two classes, eukaryotes and prokaryotes. Eukaryotes (from the Greek meaning "true kernel") have a cell nucleus that harbors most of the cell's genetic information and includes organisms such as humans, plants and fungi.

20 Apr 2022

Research reveals how RNA elements control cleavage activity of DICER enzyme in pre-miRNA and shRNAs

A research team led by scientists from the Hong Kong University of Science and Technology has revealed how secondary structure RNA elements control the cleavage activity of the DICER enzyme in both pre-miRNA and short-hairpin RNAs, improving the understanding of the DICER cleavage mechanism and providing a foundation for the design of accurate and efficient short-hairpin RNAs for gene-silencing.

20 Apr 2022

Molecular & Structural Biology

Little-known protein may play a role in frontotemporal lobar degeneration

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

New protective mechanism against non-alcoholic fatty liver disease identified

Researchers may have identified a key intermediate in the transition from prokaryotes to eukaryotes

Research reveals how RNA elements control cleavage activity of DICER enzyme in pre-miRNA and shRNAs

Double-stranded RNA provoke bone loss during periodontitis

Cryo-EM reveals the structure of fermentation enzyme phosphoketolase

A new breakthrough in the quest to improve photosynthesis in certain crops

Researchers analyze the complex function of cyanobacteria and the regulation of the biological clock

Max Planck researchers reveal the structure of kinetochore corona

Scientists gain fascinating insights into the dynamic ultrastructure of the heart

Researchers create RNA molecules to address human pancreatic beta cells

Cryo-EM imaging of STING protein reveals a new binding source for immune attacks

Combining organoids and microfluidics to study how the immune system responds to hepatitis C

A mitochondrial uncoupler prevents sarcopenic obesity in elderly mice

Researchers discover how an “accordion effect” is vital for switching off genes

Scientists recognize neuronal processes that regulate food cravings during pregnancy

Study discovers links between DNA methylation and gene expression in children

Novel method to obtain genomic data shows potential success

Certain RNA molecules may serve as markers of cellular stress in different diseases

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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