Molecular & Structural Biology

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Researchers determine small protein’s structure, likely to pave the way for advanced treatments

For the first time, researchers have deciphered the atomic structure of a protein that transports one of the body’s most vital neurotransmitters into neurons.

9 Jun 2022

Study provides new knowledge on the influence of membrane proteins on plant growth

Ubiquitin is a tiny regulatory protein that can be present in most eukaryotic cells. It is important for changing the function of other proteins, and it is especially important for protein breakdown and localization inside the cell. Ubiquitin regulates these actions through ubiquitination (attaching to and detaching from a target protein).

6 Jun 2022

Computational DNA droplet recognizes a specific combination of tumor biomarker microRNAs

The formation of aqueous droplets in macromolecules by liquid-liquid phase separation (or coacervation) is a popular topic in life sciences research. DNA is particularly interesting among the numerous macromolecules that form droplets because it is predictable and programmable, both of which are desirable properties in nanotechnology.

6 Jun 2022

Study describes the importance of the autoimmune response in bacteria

CRISPR has made headlines in recent years for its potential to help patients with conditions as diverse as blindness and sickle cell disease. However, bacteria were already using CRISPR as an immune system to combat viruses long before humans adopted it to combat genetic disorders.

3 Jun 2022

Study identifies the regulatory function of non-coding 7S RNA

In human cells, a non-coding RNA molecule controls mitochondrial gene expression, according to new research published in the journal Cell. The research is the result of a collaboration between Sweden’s University of Gothenburg and Karolinska Institutet, as well as Germany’s University of Cologne.

3 Jun 2022

Researchers analyze the chemical and biophysical properties of protein corona

Professor Chunying Chen of the Chinese Academy of Sciences’ (CAS) National Center for Nanoscience and Technology (NCNST) has been studying the chemical and biophysical characteristics of protein corona in nanomedicine.

3 Jun 2022

Researchers reveal that new compact version of Cas7-11 enzyme improves RNA editing

Cas7-11, the first CRISPR enzyme that can make precise, directed cuts to strands of RNA without hurting cells, was identified and described last year by researchers at MIT’s McGovern Institute for Brain Research.

From Massachusetts Institute of Technology (MIT) 2 Jun 2022

Study discovers new antibiotics effective against drug-resistant tuberculosis

Every year, 1.5 million people die from infections caused by Mycobacterium tuberculosis. Antibiotics are available to treat tuberculosis, but the bacteria has evolved multi-drug resistant (MDR), extensively drug-resistant (XDR), and fully drug-resistant (TDR) strains in recent years.

1 Jun 2022

Study highlights the interaction between single-stranded DNA and the linker histone H1

Human DNA is neatly locked in place around a central disc in the tight quarters of the cell nucleus by H1 linker histone that helps shepherd DNA into the tidy chromatin fibers that make up chromosomes. The linker histone, on the other hand, is much more than a protein clip.

31 May 2022

Field-grown ictB tobacco transformants show no variance in photosynthetic performance

To maintain pace with the expanding population, it is estimated that the global food supply will need to rise by 50-80% by 2050.

31 May 2022

Scientists develop powerful tools using CRISPR-Cas9 to repair genetic diseases

CRISPR has marked the beginning of a new era in genomic medicine. The popular CRISPR-Cas9 has generated plenty of potent methods for curing genetic diseases.

30 May 2022

Researchers discover a significant health food ingredient

Aggrecan, a significant component of proteoglycan (PG) in cartilaginous tissues with chondroitin sulfate (CS), is becoming more popular as a wellness food ingredient.

From Tokyo University of Science 30 May 2022

Scientists discover a new left-handed Z-DNA technique to kill hard-to-treat tumors

An international collaboration of scientists has discovered a new technique to kill cancers that are difficult to treat, according to an article published in Nature.

30 May 2022

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Research reported that the DMDRMR/miR-378a-5p/ DAB2IP axis enhances angiogenesis and sunitinib resistance, suggesting that it could be used for patients with ccRCC.

30 May 2022

Study uncovers how CD8+ T cells can divide and produce two distinct daughter cells

An immunological problem has been addressed by scientists at St. Jude Children’s Research Hospital. Despite being genetically identical, a CD8+ T cell can divide and produce two functionally different daughter cells.

27 May 2022

Research may help to predict honeybee adaptation to environmental factors

Researchers at Greece’s B.S.R.C. “Alexander Fleming” has perfected a method for identifying DNA traces in honey, indicating the species with which honeybees interact.

27 May 2022

Researchers develop a new biochemical process to analyze plant immunity

Researchers from Germany’s Max Planck Institute for Plant Breeding Research (MPIPZ) and the University of Cologne have identified a new biochemical process that explains how immune proteins protect plants against invading microbes. Their results have been reported in Cell.

From The Max Planck Institute 27 May 2022

Molecular & Structural Biology

Researchers determine small protein’s structure, likely to pave the way for advanced treatments

Study provides new knowledge on the influence of membrane proteins on plant growth

Computational DNA droplet recognizes a specific combination of tumor biomarker microRNAs

Study describes the importance of the autoimmune response in bacteria

Study identifies the regulatory function of non-coding 7S RNA

Researchers analyze the chemical and biophysical properties of protein corona

Researchers reveal that new compact version of Cas7-11 enzyme improves RNA editing

Study discovers new antibiotics effective against drug-resistant tuberculosis

Study highlights the interaction between single-stranded DNA and the linker histone H1

Field-grown ictB tobacco transformants show no variance in photosynthetic performance

Scientists develop powerful tools using CRISPR-Cas9 to repair genetic diseases

Researchers discover a significant health food ingredient

Scientists discover a new left-handed Z-DNA technique to kill hard-to-treat tumors

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Study uncovers how CD8+ T cells can divide and produce two distinct daughter cells

Research may help to predict honeybee adaptation to environmental factors

Researchers develop a new biochemical process to analyze plant immunity

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Research highlights a novel technique for cancer cells to repair DNA damage

Researchers propose new methods to save the world’s most important crops

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