Molecular & Structural Biology

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Research reveals fundamental insights into the causes of severe birth defects

Research by Kai Jiao, M.D., Ph.D., and colleagues at the University of Alabama at Birmingham and in Germany has yielded fundamental insights into the causes of severe birth defects known as CHARGE syndrome cases. These congenital birth defects include severe and life-threatening heart malformations.

3 Dec 2020

Drug meant for bacterial infections can combat weight gain

A drug originally developed to treat bacterial infections has proved capable of boosting the metabolism and attenuating the weight gain induced by a fatty diet in tests with mice. The study was conducted at the University of Campinas (UNICAMP) with FAPESP's support, and the findings have just been published in the journal Science Advances.

3 Dec 2020

Researchers identify key target that allows cancer cells to spread more efficiently

Cancer cells spread by switching on and off abilities to sense their surroundings, move, hide and grow new tumours, a new study has found.

2 Dec 2020

Study confirms that telomere shortening helps prevent cancer in humans

As time goes by, the tips of your chromosomes--called telomeres--become shorter. This process has long been viewed as an unwanted side-effect of aging, but a recent study shows it is in fact good for you.

2 Dec 2020

Research may lead to new strategies for calcium malabsorption

A Rutgers study has discovered that vitamin D regulates calcium in a section of the intestine that previously was thought not to have played a key role.

From Rutgers University 2 Dec 2020

Researchers develop new tool to study genes associated with autism spectrum disorder

Researchers have developed technology to analyze the function of different types of genes found in many types of cells in a living organism, at the same time.

1 Dec 2020

Researchers identify molecular mechanisms that reverse aging

Cellular reprogramming can reverse the aging that leads to a decline in the activities and functions of mesenchymal stem/stromal cells (MSCs).

1 Dec 2020

Protein interactions could serve as therapeutic targets to treat viral infections

Researchers have investigated the role of the interplays within the proteins membranes of viral families involved in the control of programmed cell death.

30 Nov 2020

Researchers compile new taxonomic list of vascular plants

A group of scientists have compiled the most extensive list of familiar plant species in the world.

30 Nov 2020

Study shows how telomeres protect chromosome ends

Telomeres are essentially specialized structures that are located at the end of chromosomes. These structures ensure a healthy cell division.

27 Nov 2020

Research provides new insight into how the CRISPR immune system evolved

With new insights into how the genetic tool CRISPR - which allows direct editing of our genes - evolved and adapted, we are now one step closer to understanding the basis of the constant struggle for survival that takes place in nature. The results can be used in future biotechnologies.

26 Nov 2020

Cell survival protein could protect the kidneys from 'bystander' damage during cancer therapy

Australian researchers have identified a protein that could protect the kidneys from 'bystander' damage caused by cancer therapies.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 26 Nov 2020

Study shows how bacteria develop resistance to antibiotics

A group of researchers has successfully evolved the common microorganisms Escherichia coli at the experimental level.

25 Nov 2020

Study explains why immunotherapy works on certain patients with head and neck cancer

Researchers have found new clues about why certain individuals with head and neck cancer are able to respond to immunotherapy, while others fail to do so.

25 Nov 2020

Scientists identify key biological switch used in plant defense against animal attack

For decades, scientists have known that plants protect themselves from the devastation of hungry caterpillars and other plant-munching animals through sophisticated response systems, the product of millions of years of evolution.

From UC San Diego 25 Nov 2020

Novel targeted therapy blocks critical metabolic pathways in cancer cells

Scientists have designed a new targeted therapy, known as POMHEX, which inhibits vital metabolic pathways in tumor cells containing specific genetic defects.

24 Nov 2020

Study shows how drug-like small molecules regulate the activity of ion channels

Researchers have recently discovered how the function of therapeutically relevant ion channels is regulated by drug-like small molecules.

24 Nov 2020

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active "super immune cells" with strong antitumor activity, according to new research from Georgetown Lombardi Comprehensive Cancer Center.

24 Nov 2020

Study reveals genomic structures that allow SARS-CoV-2 virus to control the infection process

An international research alliance has visualized the RNA folding structures of the SARS-CoV-2 genome, for the first time.

23 Nov 2020

Plant used in traditional Chinese medicine becomes less visible to humans

According to a new study, a plant utilized in traditional Chinese medicine has emerged to become less perceptible to human beings.

From University of Exeter 23 Nov 2020

Molecular & Structural Biology

Research reveals fundamental insights into the causes of severe birth defects

Drug meant for bacterial infections can combat weight gain

Researchers identify key target that allows cancer cells to spread more efficiently

Study confirms that telomere shortening helps prevent cancer in humans

Research may lead to new strategies for calcium malabsorption

Researchers develop new tool to study genes associated with autism spectrum disorder

Researchers identify molecular mechanisms that reverse aging

Protein interactions could serve as therapeutic targets to treat viral infections

Researchers compile new taxonomic list of vascular plants

Study shows how telomeres protect chromosome ends

Research provides new insight into how the CRISPR immune system evolved

Cell survival protein could protect the kidneys from 'bystander' damage during cancer therapy

Study shows how bacteria develop resistance to antibiotics

Study explains why immunotherapy works on certain patients with head and neck cancer

Scientists identify key biological switch used in plant defense against animal attack

Novel targeted therapy blocks critical metabolic pathways in cancer cells

Study shows how drug-like small molecules regulate the activity of ion channels

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Study reveals genomic structures that allow SARS-CoV-2 virus to control the infection process

Plant used in traditional Chinese medicine becomes less visible to humans

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