Molecular & Structural Biology

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Scientists discern molecular mechanisms underlying plant parasitism and cross-species grafting

Using the model Orobanchaceae parasitic plant Phtheirospermum japonicum, scientists from Nagoya University and other research institutes from Japan have discerned the molecular mechanisms underlying plant parasitism and cross-species grafting, pinpointing enzyme β-1,4-glucanase (GH9B3) as an important contributor to both phenomena.

12 Oct 2020

Future ocean warming and acidification could cause physical changes in marine mussels

The increased temperature and acidification of our oceans over the next century have been argued to cause significant physical changes in an economically important marine species.

12 Oct 2020

UMD researchers use AI tools to predict how and when proteins form different shapes

By applying natural language processing tools to the movements of protein molecules, University of Maryland scientists created an abstract language that describes the multiple shapes a protein molecule can take and how and when it transitions from one shape to another.

12 Oct 2020

Scientists shed light on immune evasion strategy used by malaria-causing parasite

The Plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers changes in human genes that alter the body's adaptive immune response to malarial infections, according to a team of researchers at NYU Abu Dhabi.

12 Oct 2020

New radioimmunotherapy effectively reverses resistance to lymphoma therapy

A new radioimmunotherapy has proven effective in reversing resistance to the most commonly used lymphoma drug, rituximab, according to research published in the October issue of The Journal of Nuclear Medicine.

9 Oct 2020

Too many genetic exchanges impede chromosome segregation into eggs

The exchange of DNA between chromosomes during the early formation of sperm and egg cells normally is limited to assure fertility.

9 Oct 2020

New approach to determine the structure of large RNA molecules

Researchers have designed a new technique to establish the structures of huge RNA molecules at high resolution.

9 Oct 2020

Researchers demonstrate mysterious molecular concept for targeted drug delivery

Researchers have demonstrated a type of cellular binding that could lead to highly targeted treatments against diseases like cancer.

8 Oct 2020

New method reveals structural data of membrane proteins in explicit detail

The human body contains a vast number of proteins that are collectively called the proteome.

8 Oct 2020

New machine learning algorithms to analyze reams of RNA-based 'toehold' sequences

DNA and RNA have been compared to "instruction manuals" containing the information needed for living "machines" to operate.

7 Oct 2020

Maternal high sugar diet can impact developmental outcomes in infants

A diet high in sugar during adulthood is associated with weight gain, and has also been linked to risk of type 2 diabetes, fatty liver disease, and heart disease. New research shows that when consumed by moms during the breastfeeding period, a high sugar diet can also impact developmental outcomes during infancy.

7 Oct 2020

Researchers investigate the role of auxin in regulating pathogen gene expression

Scientists have long known that the plant hormone auxin controls many aspects of plant growth, development, and responses to the environment. Only more recently have they begun to understand that there is also a link between auxin and leaf spotting diseases.

7 Oct 2020

New method can help test vaccine formulations

Scientists are casting a net for nanoparticles. They have now identified a new technique for producing nanoparticles from a simple, self-assembling polymer.

6 Oct 2020

CAR T cell therapy can predict treatment outcomes in patients with large B-cell lymphoma

Scientists have identified cellular and molecular features of anti-CD19 CAR T cell infusion products that are correlated with large B-cell lymphoma (LBCL).

6 Oct 2020

High folic acid levels during pregnancy affect brain development of mouse embryos

A UC Davis MIND Institute study of pregnant mice found that high amounts of folic acid during pregnancy harmed the brain development of embryos.

From The University of California, Davis 6 Oct 2020

Cancer mutations occur in distinct patterns based on 3D structure of the genome

A new study from researchers at The University of Texas MD Anderson Cancer Center has discovered that mutations found in cancers do not accumulate randomly, but are found in distinct patterns that vary based on the three-dimensional organization of the genome in the cell as well as the underlying factors causing the mutations.

6 Oct 2020

Researchers identify small molecules that appear to reduce cellular stress

For many, getting older can unfortunately mean an increased risk of illness from cardiovascular disease to cancer. University of Michigan scientists are actively researching the biological underpinnings of aging with the aim of developing interventions that could potentially help people live longer, healthier lives.

6 Oct 2020

Researchers use physics to map the chaos of movement in living organisms

The behavior of living organisms might obey the same mathematical laws as physical phenomena, such as weather and the motion of planets, says new research from the Biological Physics Theory Unit at the Okinawa Institute of Science and Technology Graduate University.

6 Oct 2020

Researchers identify new DNA fragment that forms male sex organs in mice

Researchers have identified a new piece of DNA that is crucial for the formation of male sex organs. This discovery may require the revisal of biology textbooks.

5 Oct 2020

Study shows patients can benefit from personalized cancer therapy

Scientists have shown that patients, who are receiving care for cancer, have a greater chance of surviving if they received personalized cancer treatment.

From UC San Diego 5 Oct 2020

Molecular & Structural Biology

Scientists discern molecular mechanisms underlying plant parasitism and cross-species grafting

Future ocean warming and acidification could cause physical changes in marine mussels

UMD researchers use AI tools to predict how and when proteins form different shapes

Scientists shed light on immune evasion strategy used by malaria-causing parasite

New radioimmunotherapy effectively reverses resistance to lymphoma therapy

Too many genetic exchanges impede chromosome segregation into eggs

New approach to determine the structure of large RNA molecules

Researchers demonstrate mysterious molecular concept for targeted drug delivery

New method reveals structural data of membrane proteins in explicit detail

New machine learning algorithms to analyze reams of RNA-based 'toehold' sequences

Maternal high sugar diet can impact developmental outcomes in infants

Researchers investigate the role of auxin in regulating pathogen gene expression

New method can help test vaccine formulations

CAR T cell therapy can predict treatment outcomes in patients with large B-cell lymphoma

High folic acid levels during pregnancy affect brain development of mouse embryos

Cancer mutations occur in distinct patterns based on 3D structure of the genome

Researchers identify small molecules that appear to reduce cellular stress

Researchers use physics to map the chaos of movement in living organisms

Researchers identify new DNA fragment that forms male sex organs in mice

Study shows patients can benefit from personalized cancer therapy

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