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A mitochondrial uncoupler prevents sarcopenic obesity in elderly mice

A recently discovered chemical compound helped elderly mice with obesity lose fat and weight, add muscle and strength, reduce age-related inflammation and increase physical activity, a new study shows.

7 Apr 2022

Specialist assay kits and microplates for cancer research

Porvair Sciences will exhibit its latest assay kits and microplates for cancer and life science research at the American Association for Cancer Research (AACR) meeting in New Orleans, USA from the 8th – 13th April 2022.

From Porvair Sciences Limited 7 Apr 2022

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

If we want to enhance our knowledge and treatment of Alzheimer’s disease, we need to identify genetic risk factors.

7 Apr 2022

Breakthrough discovery provides a desirable drug target to tackle metabolic diseases

In a breakthrough discovery, scientists from The University of Texas Health Science Center at San Antonio today reported that inhibiting a liver enzyme in obese mice decreased the rodents' appetite, increased energy expenditure in adipose (fat) tissues and resulted in weight loss.

6 Apr 2022

Gut microbiota may play a role in resistance to blood pressure medicines

Almost half of the U.S. adult population has high blood pressure - or hypertension - and about 20% of these patients have treatment-resistant hypertension.

6 Apr 2022

A critical subset of supporting cells may lie at the origins of scleroderma

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022

Biologists unravel the mystery behind nuclear anomaly in blood cancer cells

The mystery is being unraveled of why the control centers, or nuclei, of certain blood cancer cells have a distinctly odd shape.

5 Apr 2022

Proteins in saliva could serve as a biomarker to identify patients at risk for severe COVID-19

Researchers have identified a family of proteins that is significantly elevated in the saliva of patients hospitalized with COVID-19.

5 Apr 2022

Researchers identify new set of protein biomarkers for cancer using breast milk

A simple blood test for women of all ages and risk levels could one day be possible thanks to a new set of protein biomarkers that researchers identified using breast milk.

5 Apr 2022

Genetic risk score may help identify Type 2 diabetes patients with a higher risk for cardiovascular events

A risk score based on a gene map predicted the likelihood of high blood pressure leading to heart problems or stroke in people with Type 2 diabetes, according to a study published today in the American Heart Association's peer-reviewed journal Hypertension.

5 Apr 2022

Older rats more vulnerable to caffeine-induced ventricular tachyarrhythmia than younger ones

The Food and Drug Administration recommends healthy adults not exceed 400 milligrams (mg) of caffeine-; approximately four cups of brewed coffee-; a day.

4 Apr 2022

Experimental "gene silencing" therapy reduces a important driver of heart disease risk by up to 98%

Findings from a new Cleveland Clinic-led phase 1 trial show that an experimental "gene silencing" therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%.

4 Apr 2022

High-resolution 3D map reveals cellular structure of the human metathalamus

A new, high-resolution 3D map of a previously unmapped area of the brain has been reconstructed by a team of researchers as part of the Human Brain Project (HBP). The German-based group developed a cytoarchitectonic map (a map of the cellular structure of the brain, down to the individual neurons) of the metathalamus, an area involved in processing audiovisual information.

4 Apr 2022

Plant compound may be a good therapeutic candidate for treating food allergies

Researchers combined advanced computational methods with experimental studies to gain new insight, at the cell level, into how the plant compound formononetin might be used to treat food allergies.

4 Apr 2022

Scientists produce the first complete, gapless sequence of a human genome

Two decades after the Human Genome Project delivered the first preliminary human genome sequence, researchers have published the first full, gapless sequence of a human genome.

From National Human Genome Research Institute (NHGRI) 4 Apr 2022

Using a microfluidic chip for selection of healthy sperm based on positive rheotaxis

The female genital tract can be a hostile environment for conception. Out of about 100 million sperm, only a few hundred make it to the fallopian tubes.

1 Apr 2022

Lifebit; Making Biomedical Data Accessible

In this interview, we speak to Dr. Maria Chatzou Dunford, CEO of Lifebit, about their technology and how it helps scientists to make better use of their data.

From Lifebit 1 Apr 2022

Researchers discover abnormal gene mutations that lead to cancer development

The reason why the control centers, or nuclei, of certain blood cancer cells, have a peculiar structure is still a mystery.

1 Apr 2022

HIF-1alpha inhibitor preserves the activity of insulin-producing beta cells in diabetic mice

High blood glucose is responsible for several complications in type 1 and type 2 diabetes. Researchers at Karolinska Institutet in Sweden have identified a new antidiabetic substance that preserves the activity of insulin-producing beta cells and prevents high blood glucose in mice.

31 Mar 2022

Study on key protein offers clues into the origin of mesothelioma

Researchers at the University of Colorado Anschutz Medical Campus and their international collaborators have discovered that a protein critical in the embryonic stages of life is reactivated in certain cases of mesothelioma, offering clues into the origin of this aggressive cancer.

30 Mar 2022

Clinical News and Research

A mitochondrial uncoupler prevents sarcopenic obesity in elderly mice

Specialist assay kits and microplates for cancer research

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

Breakthrough discovery provides a desirable drug target to tackle metabolic diseases

Gut microbiota may play a role in resistance to blood pressure medicines

A critical subset of supporting cells may lie at the origins of scleroderma

Biologists unravel the mystery behind nuclear anomaly in blood cancer cells

Proteins in saliva could serve as a biomarker to identify patients at risk for severe COVID-19

Researchers identify new set of protein biomarkers for cancer using breast milk

Genetic risk score may help identify Type 2 diabetes patients with a higher risk for cardiovascular events

Older rats more vulnerable to caffeine-induced ventricular tachyarrhythmia than younger ones

Experimental "gene silencing" therapy reduces a important driver of heart disease risk by up to 98%

High-resolution 3D map reveals cellular structure of the human metathalamus

Plant compound may be a good therapeutic candidate for treating food allergies

Scientists produce the first complete, gapless sequence of a human genome

Using a microfluidic chip for selection of healthy sperm based on positive rheotaxis

Lifebit; Making Biomedical Data Accessible

Researchers discover abnormal gene mutations that lead to cancer development

HIF-1alpha inhibitor preserves the activity of insulin-producing beta cells in diabetic mice

Study on key protein offers clues into the origin of mesothelioma

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