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AI and robotics identify new cellular hallmarks of Parkinson's disease

A study published today in Nature Communications unveils a new platform for discovering cellular signatures of disease that integrates robotic systems for studying patient cells with artificial intelligence methods for image analysis.

28 Mar 2022

Minuscule involuntary eye movements are not drivers of brain signals underlying attention

Minuscule involuntary eye movements, known as microsaccades, can occur even while one is carefully staring at a fixed point in space.

28 Mar 2022

Scientists create powerful new method for generating protein drugs

A team of scientists has created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable proteins on the surface of viruses.

28 Mar 2022

CDH17CAR T cells can eliminate solid tumors without damaging healthy tissues

Chimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and lymphomas, but there are no successful immunotherapies for neuroendocrine tumors (NETs) and gastrointestinal cancers (GICs) yet.

25 Mar 2022

CAR-T cell treatment via implantable biotechnology more effective in combating cancer

Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed an implantable biotechnology that produces and releases CAR-T cells for attacking cancerous tumors.

25 Mar 2022

New discovery likely to result in cancer vaccine development

According to research published in eLife, researchers have developed a pipeline for detecting, prioritizing, and testing potential tumor antigens for the rapid development of cancer vaccines.

23 Mar 2022

Study shows how genes help control appetite and obesity in children

Have you ever noticed why little newborns gain weight at varying rates and in varying amounts during their early years of life?

23 Mar 2022

Research reveals how a marine bacterium makes a potent anti-cancer molecule

Years of toil in the laboratory have revealed how a marine bacterium makes a potent anti-cancer molecule.

22 Mar 2022

Scientists reveal how 9-1-1 clamp attaches to DNA damage site for initiating effective repair

DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.

22 Mar 2022

Microbial communities with auxotrophs more likely to have increased drug tolerance, study finds

Research from the Francis Crick Institute has revealed a key mechanism which increases tolerance to drugs amongst microbial communities.

22 Mar 2022

Transcriptomic analysis of Alzheimer's patients reveals early organelle dysfunction in astrocytes

An international group of researchers led by the UAB analyzed the genes that are expressed in neurons and astrocytes based on data from 800 individuals and compared what happens in Alzheimer's patients and in people without diagnosed dementia.

21 Mar 2022

Researchers investigate genomic data discrepancies among racial groups

The Cancer Genome Atlas, one of the biggest cancer research databases, was used by Mayo Clinic researchers to investigate disparities in genomic data quality.

21 Mar 2022

Novel method to sneak large drug-carrying biological molecules into cells

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a novel method of delivering drugs into human cells using large biological molecules, by first encasing them in a protein-based microdroplet.

From Nanyang Technological University Singapore (NTU Singapore) 17 Mar 2022

Scientists use mRNA delivery to enhance muscle power

Mutations that cause muscle atrophy can be corrected using the CRISPR-Cas9 gene-editing tool.

16 Mar 2022

Novel “green” synthesis of drug for inflammatory bowel disease

Steroids and antibody drugs are currently used to treat inflammatory bowel disease (IBD), which is characterized by chronic inflammation of the digestive tract.

16 Mar 2022

Scientists develop a new computational biology method to better understand IBD

Around 500,000 people in the UK live with Inflammatory Bowel Disease (IBD), a life-long, chronic condition characterized by sporadic bouts of gut inflammation causing debilitating symptoms.

15 Mar 2022

Cellular therapy leads to meaningful functional improvements in DMD patients

A clinical trial at UC Davis Health and six other sites showed that a cellular therapy offers promise for patients with late-stage Duchenne muscular dystrophy (DMD), a rare genetic disorder causing muscle loss and physical impairments in young people.

From The University of California, Davis 14 Mar 2022

Improving the long-term effectiveness of TB vaccine in mice

Briefly blocking a key molecule when administering the only approved vaccine for tuberculosis vastly improves long-term protection against the devastating disease in mice, researchers from Texas Biomedical Research Institute report this week in the Journal of Immunology.

14 Mar 2022

New PRMC-MS method enables comprehensive analysis of membrane lipids

The development of new scientific ways to see more deeply into the building blocks of nature on a cellular level has led to the some of the greatest advances in medicine over the last century.

11 Mar 2022

Yale researchers find a way to 'supercharge' tumor-attacking T cells

Yale scientists have identified a way to "supercharge" tumor-attacking T cells, a finding that may not only improve the effectiveness of a promising type of cell-based cancer immunotherapy but also expand the number of cancers it can treat.

11 Mar 2022