Clinical News and Research

RSS

A “stress test” with a previously unknown gene to revive the exhausted T cells

The task of battling cancer cells can fatigue T cells employed in immunotherapy treatments, or they could shut down once they penetrate tumors. Researchers at the Gladstone Institutes and UC San Francisco have strengthened the therapeutic cells’ resistance via a CRISPR-based edit on their genomes.

30 Aug 2022

The complex link between pancreatic malformations and the “dark genome”

For the first time, scientists at the Centre for Genomic Regulation (CRG) have discovered a DNA sequence that is essential for pancreatic development and function.

25 Aug 2022

Microbiomes can help cure food allergies in mice

Many people with dietary allergies may have minor symptoms when they consume foods that trigger them, but for some, the consequences could be lethal. In lab experiments, a bacterial chemical called butyrate produced by healthy microbiomes has shown promise in preventing allergy reactions, but it is unpleasant to consume.

23 Aug 2022

Mayo Clinic's strategic collaboration in biomanufacturing focuses on delivering novel biotherapeutics

Mayo Clinic today announced a strategic collaboration in biomanufacturing to deliver novel biotherapeutics for rare and complex conditions.

17 Aug 2022

Extract from the roots of Rhodiola rosea may be effective for managing type 2 diabetes

A team of researchers led by the University of California, Irvine has discovered that treatment with an extract from the roots of the Rhodiola rosea plant might be effective for helping manage type 2 diabetes, showing promise as a safe and effective non-pharmaceutical alternative.

16 Aug 2022

Inventia Life Science Accelerates Growth with AU$35 million Series B Led by Blackbird Ventures, Launching 3D Cell Culture Platform into US Market

Company aims to democratise access to affordable biomedical research especially in cancer research and new drug development through its novel 3D cell culture platform

From Inventia Life Science 16 Aug 2022

Inventia Life Science partners with Xylyx Bio to develop tissue-specific, digitally-printed bioinks for drug discovery

Inventia Life Science and Xylyx Bio today announced their strategic partnership following promising results developing more realistic, scalable, and reproducible 3D cell cultures for drug discovery and biomedical research.

From Inventia Life Science 16 Aug 2022

Mount Sinai and Regeneron Genetics Center launch a large-scale genome sequencing project

Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.

12 Aug 2022

Fabimycin likely to be an effective treatment for drug-resistant bacteria

Bacteria that cause urinary tract infections are getting more and more resistant to many medications, and they are becoming more and more difficult to cure.

12 Aug 2022

Study provides guidelines on how to design safer CRISPR reagents

The 2020 Nobel Prize in Chemistry was awarded to Jennifer A. Doudna and Emmanuelle Charpentier for developing the widely utilized and incredibly precise genome editing method known as CRISPR/Cas9

11 Aug 2022

Researchers report the identification of novel small molecules that stimulate human adaptive immune responses

An antibody that is successfully used to treat a variety of tumors has been replaced with a tiny molecule that researchers from Tel Aviv University and the University of Lisbon have jointly found and manufactured.

9 Aug 2022

Researchers create CAR T cells for cancer immunotherapy

In CAR T-cell immunotherapy, T cells taken from the patient’s own blood are modified to contain so-called chimeric antigen receptors (CAR), which provide the T cells the ability to target and eradicate tumor cells.

8 Aug 2022

Mitochondrial DNA plays a crucial role in inflammation, study finds

Mitochondria are generally known as the powerhouse of the cell, however, growing research indicates that they may potentially be involved in inflammation.

8 Aug 2022

Optogenetic control of mitochondria–lysosome contacts induce mitochondrial fission with spatiotemporal accuracy

Researchers from UC, the University of Illinois Urbana-Champaign, and the University at Buffalo demonstrated that light-activated proteins can help normalize dysfunction within cells.

8 Aug 2022

SLFN11’s surveillance part in protein homeostasis

On July 25th, 2022, a new study perspective called “SLFN11’s surveillance role in protein homeostasis” was published in Volume 9 of Oncoscience.

8 Aug 2022

Researchers make significant improvements to PubCaseFinder, the clinical decision support system

Even medical professionals with years of experience can spend hours researching potential illnesses in reliable medical sources (such as databases, books, and literature) to identify which diseases have phenotypic traits overlapping with the phenotypes of undiagnosed patients.

8 Aug 2022

Active immune cells provide great protection against ischemic stroke

According to research published today in the Journal of Clinical Investigation by neurologists and immunologists at the University of Pittsburgh, a special subgroup of white blood cells provides mice with quick-acting and long-lasting protection against ischemic stroke.

From University of Pittsburgh 3 Aug 2022

Genomics plays a major role in psychedelic drugs behavior

It can be crippling for those who suffer from conditions like depression, anxiety, and cluster headaches. In clinical research, psychedelic substances have demonstrated benefits as therapies for several ailments, but not in all cases.

1 Aug 2022

Researchers propose a solution to delayed molecular diagnosis and therapy in childhood genetic diseases

Rady Children’s Institute for Genomic Medicine (RCIGM®) recently announced the publication in Nature Communications of research that describes and examines the efficiency of Genome-to-Treatment (GTRxTM), a computer-controlled, virtual disease management system that combines a quick Whole Genome Sequencing (rWGS®) diagnosis accomplished in 13.5 hours with a custom lab management information system and analysis pipeline.

28 Jul 2022

COVID-19 spike protein caused severe heart damage, new research shows

Heart damage is prevalent in COVID-19 patients, leading many to doubt how the virus impacts the heart.

28 Jul 2022

Clinical News and Research

A “stress test” with a previously unknown gene to revive the exhausted T cells

The complex link between pancreatic malformations and the “dark genome”

Microbiomes can help cure food allergies in mice

Mayo Clinic's strategic collaboration in biomanufacturing focuses on delivering novel biotherapeutics

Extract from the roots of Rhodiola rosea may be effective for managing type 2 diabetes

Inventia Life Science Accelerates Growth with AU$35 million Series B Led by Blackbird Ventures, Launching 3D Cell Culture Platform into US Market

Inventia Life Science partners with Xylyx Bio to develop tissue-specific, digitally-printed bioinks for drug discovery

Mount Sinai and Regeneron Genetics Center launch a large-scale genome sequencing project

Fabimycin likely to be an effective treatment for drug-resistant bacteria

Study provides guidelines on how to design safer CRISPR reagents

Researchers report the identification of novel small molecules that stimulate human adaptive immune responses

Researchers create CAR T cells for cancer immunotherapy

Mitochondrial DNA plays a crucial role in inflammation, study finds

Optogenetic control of mitochondria–lysosome contacts induce mitochondrial fission with spatiotemporal accuracy

SLFN11’s surveillance part in protein homeostasis

Researchers make significant improvements to PubCaseFinder, the clinical decision support system

Active immune cells provide great protection against ischemic stroke

Genomics plays a major role in psychedelic drugs behavior

Researchers propose a solution to delayed molecular diagnosis and therapy in childhood genetic diseases

COVID-19 spike protein caused severe heart damage, new research shows

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics